3-BROMO-1H-PYRAZOLE
- CAS No.
- 14521-80-3
- Chemical Name:
- 3-BROMO-1H-PYRAZOLE
- Synonyms
- 3-Bromopyrazole 97%;MFCD13189492;3-BROMO-PYRAZOLE;3-BROMO-1H-PYRAZOLE;3-bromo-2H-pyrazole;1H-PYRAZOLE, 3-BROMO-;1H-Pyrazole,3-bromo-(9CI);3-Bromo-1H-Pyrazole(WX900043);3-Bromopyrazole/3-broMo-1H-pyrazole
- CBNumber:
- CB1121665
- Molecular Formula:
- C3H3BrN2
- Molecular Weight:
- 146.97
- MDL Number:
- MFCD01646049
- MOL File:
- 14521-80-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Bromopyrazole 97% | 723924 | 1g | $170 |
| 3-Bromopyrazole 97% | 723924 | 500mg | $123 |
| 3-Bromopyrazole | B687345 | 1g | $45 |
| 3-Bromopyrazole 97% | 067227 | 1g | $49 |
| 3-Bromo-1H-pyrazole 95% | CAPOB13736 | 1g | $50 |
| More product size | |||
| Melting point | 60-65°C |
|---|---|
| Boiling point | 70-72 °C(Press: 0.1 Torr) |
| Density | 1.904±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 10.88±0.10(Predicted) |
| form | crystals |
| color | White-pale yellow |
| InChI | InChI=1S/C3H3BrN2/c4-3-1-2-5-6-3/h1-2H,(H,5,6) |
| InChIKey | XHZWFUVEKDDQPF-UHFFFAOYSA-N |
| SMILES | N1C=CC(Br)=N1 |
| CAS DataBase Reference | 14521-80-3 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 1 |
| HS Code | 2933119000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
3-BROMO-1H-PYRAZOLE price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 723924 | 3-Bromopyrazole 97% | 14521-80-3 | 1g | $170 | 2025-07-31 | Buy |
| Sigma-Aldrich | 723924 | 3-Bromopyrazole 97% | 14521-80-3 | 500mg | $123 | 2023-06-20 | Buy |
| TRC | B687345 | 3-Bromopyrazole | 14521-80-3 | 1g | $45 | 2021-12-16 | Buy |
| Matrix Scientific | 067227 | 3-Bromopyrazole 97% | 14521-80-3 | 1g | $49 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | CAPOB13736 | 3-Bromo-1H-pyrazole 95% | 14521-80-3 | 1g | $50 | 2021-12-16 | Buy |
3-BROMO-1H-PYRAZOLE Chemical Properties,Uses,Production
Uses
3-Bromopyrazole is a useful synthetic intermediate in the synthesis of Rynaxypyr (C325380); an insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activator.
Synthesis
500011-84-7
14521-80-3
General procedure for the synthesis of 3-bromopyrazole from 1-(dimethylaminosulfonyl)-3-bromopyrazole: 3-bromo-N,N-dimethyl-1H-pyrazole-1-sulfonamide (5.83 g) obtained in step B was mixed with trifluoroacetic acid (9.0 mL) and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, ethyl acetate was added to the mixture, followed by neutralization of the reaction solution with saturated aqueous sodium bicarbonate and washing with saturated aqueous sodium chloride. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by silica gel column chromatography (eluent: ethyl acetate/hexane) to give the final target compound 3-bromopyrazole (2.92 g). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 6.37 (1H, d, J=2.4 Hz), 7.57 (1H, d, J=2.4 Hz).
References
[1] Patent: WO2006/68669, 2006, A1. Location in patent: Page/Page column 19; 24
[2] Patent: WO2003/106427, 2003, A2. Location in patent: Page 18
[3] Patent: WO2004/11447, 2004, A2. Location in patent: Page 42-43
[4] Patent: EP2818473, 2014, A1. Location in patent: Paragraph 0583
[5] Patent: US9113630, 2015, B2. Location in patent: Page/Page column 41; 42
3-BROMO-1H-PYRAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3982 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 3-BROMO-1H-PYRAZOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | 3-Bromo-1H-pyrazole
14521-80-3
|
US $130.00-850.00 / g | 1g | 99.2% | 20tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-01-30 | 3-BROMO-1H-PYRAZOLE
14521-80-3
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-11-15 | 3-bromo-pyrazole
14521-80-3
|
US $0.00 / KG | 1KG | 99% | 20 tons | Qiuxian Baitai New Material Co., LTD |
-
- 3-Bromo-1H-pyrazole
14521-80-3
- US $130.00-850.00 / g
- 99.2%
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-BROMO-1H-PYRAZOLE
14521-80-3
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-bromo-pyrazole
14521-80-3
- US $0.00 / KG
- 99%
- Qiuxian Baitai New Material Co., LTD
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