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2-Hydroxycyclohexanecarboxylic acid

CAS No.
609-69-8
Chemical Name:
2-Hydroxycyclohexanecarboxylic acid
Synonyms
2-Hydroxycyclohexanecarboxylic acid;2-hydroxycyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 2-hydroxy-;2-HydroxycyclohexanecarboxylicAcid(cis-andtrans-mixture)>2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- Mixture);2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture)
CBNumber:
CB1470352
Molecular Formula:
C7H12O3
Molecular Weight:
144.17
MDL Number:
MFCD02684437
MOL File:
609-69-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:49:14

2-Hydroxycyclohexanecarboxylic acid Properties

Melting point 67.0 to 71.0 °C
Boiling point 307.9±35.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka 4.95±0.28(Predicted)
color White to Almost white
CAS DataBase Reference 609-69-8

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
HS Code  2918199890

2-Hydroxycyclohexanecarboxylic acid price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical H1409 2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) >98.0%(GC)(T) 609-69-8 1g $198 2026-04-30 Buy
TCI Chemical H1409 2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) >98.0%(GC)(T) 609-69-8 5g $702 2026-04-30 Buy
Apolloscientific OR912806 2-Hydroxycyclohexanecarboxylic acid 95% 609-69-8 250mg $300 2026-06-04 Buy
Apolloscientific OR912806 2-Hydroxycyclohexanecarboxylic acid 95% 609-69-8 1g $592 2026-06-04 Buy
Matrix Scientific 307022 2-Hydroxycyclohexanecarboxylic acid 609-69-8 100.00mg $50 2026-05-19 Buy
Product number Packaging Price Buy
H1409 1g $198 Buy
H1409 5g $702 Buy
OR912806 250mg $300 Buy
OR912806 1g $592 Buy
307022 100.00mg $50 Buy

2-Hydroxycyclohexanecarboxylic acid Chemical Properties, Uses, Production

Definition

ChEBI: 2-hydroxycyclohexanecarboxylic acid is a hydroxy monocarboxylic acid. It is functionally related to a cyclohexanecarboxylic acid.

Synthesis

Carbon dioxide

124-38-9

Cyclohexene oxide

286-20-4

2-HYDROXYCYCLOHEXANECARBOXYLIC ACID

609-69-8

2-HYDROXYCYCLOHEXANECARBOXYLIC ACID

609-69-8

In the first step, 9.8 kg (100 mol) of epoxycyclohexane was dissolved in 50 L of N-methylpyrrolidone (NMP). Under continuous stirring, 2.88 kg (120 mol) of magnesium powder was slowly added and the temperature of the reaction system was controlled between -15 °C and -5 °C. Subsequently, 19.5 kg (180 mol) of trimethylchlorosilane (TMSCl) was added dropwise while carbon dioxide gas was vented. The reaction was carried out for 10 h to ensure that the reaction was complete, keeping the temperature below 0 °C. The reaction mixture was filtered and the filtrate was slowly added to a 1 N hydrochloric acid solution. The pH of the mixture was adjusted to 3-4 and extracted with 80 L of ethyl acetate in two portions. The organic phase was washed with a half-saturated aqueous salt solution and concentrated by distillation to give 13.8 kg (95.8 mol) of 2-hydroxycyclohexanecarboxylic acid in 95.8% yield with a cis-trans isomer ratio of 2.3:7.7.

References

[1] Patent: CN108383719, 2018, A. Location in patent: Paragraph 0018; 0023; 0024

108-94-1
609-69-8
Synthesis of 2-Hydroxycyclohexanecarboxylic acid from Cyclohexanone
Global Suppliers ( 80)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3901 58
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23636 75
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55

View Latest Price from 2-Hydroxycyclohexanecarboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Hydroxycyclohexanecarboxylic acid pictures 2022-02-19 2-Hydroxycyclohexanecarboxylic acid
609-69-8
1KG 99.1% 100 tons Honest Joy Holdings Limited
2-HYDROXYCYCLOHEXANECARBOXYLIC ACID pictures 2019-12-20 2-HYDROXYCYCLOHEXANECARBOXYLIC ACID
609-69-8
$1.00 1KG 99% Career Henan Chemical Co
2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- mixture) 2-Hydroxycyclohexanecarboxylic Acid (cis- and trans- Mixture) 2-HydroxycyclohexanecarboxylicAcid(cis-andtrans-mixture)> Cyclohexanecarboxylic acid, 2-hydroxy- 2-hydroxycyclohexane-1-carboxylic acid 2-Hydroxycyclohexanecarboxylic acid 609-69-8 HOC6H10COOH pharmacetical