3-Amino-2-pyridinecarboxylic acid
- CAS No.
- 1462-86-8
- Chemical Name:
- 3-Amino-2-pyridinecarboxylic acid
- Synonyms
- 3-AMINOPICOLINIC ACID;3-AMINO-PYRIDINE-2-CARBOXYLIC ACID;2-Pyridinecarboxylic acid, 3-amino-;AKOS 92172;H-3APC2-OH;IFLAB-BB F2113-0045;RARECHEM AQ NN 0176;3-AMINO-2-PICOLINIC ACID;3-Amino-α-picolinic acid;3-Amino-2-carboxypyridine
- CBNumber:
- CB1487480
- Molecular Formula:
- C6H6N2O2
- Molecular Weight:
- 138.12
- MDL Number:
- MFCD00090153
- MOL File:
- 1462-86-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 218-220 |
|---|---|
| Boiling point | 386.6±27.0 °C(Predicted) |
| Density | 1.417±0.06 g/cm3(Predicted) |
| RTECS | US5175000 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Soluble in acetone, ethanol and methanol. |
| pka | 1.32±0.50(Predicted) |
| form | Solid |
| color | Yellow to pale brown |
| InChI | InChI=1S/C6H6N2O2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,7H2,(H,9,10) |
| InChIKey | BOOMHTFCWOJWFO-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=NC=CC=C1N |
| CAS DataBase Reference | 1462-86-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | KRX7SG6NCS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37-60 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
3-Amino-2-pyridinecarboxylic acid price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-A627800-5G | 3-Aminopicolinic Acid | 1462-86-8 | 5g | $117 | 2026-06-03 | Buy |
| TRC | TRC-A627800-1G | 3-Aminopicolinic Acid | 1462-86-8 | 1g | $59 | 2026-06-03 | Buy |
| AstaTech | CL0127 | 3-AMINO-2-PYRIDINECARBOXYLIC ACID 95% | 1462-86-8 | 1G | $19 | 2026-04-30 | Buy |
| AstaTech | CL0127 | 3-AMINO-2-PYRIDINECARBOXYLIC ACID 95% | 1462-86-8 | 5G | $27 | 2026-04-30 | Buy |
| AstaTech | CL0127 | 3-AMINO-2-PYRIDINECARBOXYLIC ACID 95% | 1462-86-8 | 25G | $115 | 2026-04-30 | Buy |
3-Amino-2-pyridinecarboxylic acid Chemical Properties,Uses,Production
Chemical Properties
Green/Brown Crystals
Uses
3-Amino-2-pyridinecarboxylic acid is a useful synthetic intermediate.
Uses
Employed as an important intermediate for syntheses material and pharmaceutical.
Application
3-Aminopicolinic Acid is used in the preparation of piperidinyl-methyl-purinamines as NSD2 inhibitors and anti-cancer agents.
Synthesis
59290-85-6
1462-86-8
(2) Preparation of 3-aminopyridine-2-carboxylic acid: 3-nitropyridine-2-carboxylic acid (2.72 g, 16.2 mmol) and sodium bicarbonate (1.34 g, 16.2 mmol) were dissolved in distilled water (20 mL). The atmosphere in the system was replaced with nitrogen to exclude oxygen. After adding 10% palladium carbon catalyst (1.72 g), the atmosphere in the system was replaced with hydrogen and the reaction was stirred at room temperature for 50 hours. After completion of the reaction, the pH of the reaction solution was adjusted to weakly acidic by adding 1N aqueous hydrochloric acid. The solvent was removed by distillation under reduced pressure and a small amount of ethanol and ethyl acetate was added to the residue and the resulting precipitate was collected by filtration. The filtrate was concentrated to afford the target product 3-aminopyridine-2-carboxylic acid (1.50 g, 67% yield) as a light yellow solid.
References
[1] Patent: US2005/182045, 2005, A1. Location in patent: Page/Page column 74
3-Amino-2-pyridinecarboxylic acid Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiaxing Hengrui Biotechnology Co. LTD | 0573-0573-82672231 13757365595 | regen_chemical1@163.com | China | 4858 | 58 |
| Nanjing Henghua Pharmaceutical Technology Co., Ltd | 15862800858 | 173990752@qq.com | China | 25 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Lastest Price from 3-Amino-2-pyridinecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 3-Amino-2-pyridinecarboxylic acid
1462-86-8
|
$9.80 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2019-07-06 | 3-Amino-2-pyridinecarboxylic acid
1462-86-8
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- 3-Amino-2-pyridinecarboxylic acid
1462-86-8
- $9.80
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Amino-2-pyridinecarboxylic acid
1462-86-8
- $1.00
- 99%
- Career Henan Chemical Co
