3-Aminopyridine-2-carboxylic acid methyl ester
- CAS No.
- 36052-27-4
- Chemical Name:
- 3-Aminopyridine-2-carboxylic acid methyl ester
- Synonyms
- Methyl 3-aminopicolinate;3-aminopyridine-2-methyl formate;methyl 3-aminopyridine-2-carboxylate;Methyl 3-amino-2-pyridine carboxylate;3-Aminopyridine-2-carboxylic acid methyl ester;2-Pyridinecarboxylic acid, 3-aMino-, Methyl ester;2-Pyridinecarboxylicacid,3-amino-,methylester(9CI);3-amino-2-Pyridinecarboxylic acid methyl ester (9CI ACI);3-AMINOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(RS20012789);2-Pyridinecarboxylic acid, 3-amino-, methyl ester (9CI, ACI)
- CBNumber:
- CB7967401
- Molecular Formula:
- C7H8N2O2
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD08695602
- MOL File:
- 36052-27-4.mol
- MSDS File:
- SDS
| Boiling point | 317.3±22.0 °C(Predicted) |
|---|---|
| Density | 1.238±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 2.65±0.10(Predicted) |
| Appearance | White to yellow Solid |
| InChI | InChI=1S/C7H8N2O2/c1-11-7(10)6-5(8)3-2-4-9-6/h2-4H,8H2,1H3 |
| InChIKey | YQKTYFNLRUWQFV-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)=NC=CC=C1N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335-H302 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| HS Code | 2933399990 |
3-Aminopyridine-2-carboxylic acid methyl ester price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM139560 | Methyl 3-aminopicolinate | 36052-27-4 | 2g | $219.88 | 2026-06-04 | Buy |
| Biosynth | FM139560 | Methyl 3-aminopicolinate | 36052-27-4 | 5g | $314.1 | 2026-06-04 | Buy |
| Biosynth | FM139560 | Methyl 3-aminopicolinate | 36052-27-4 | 10g | $471.2 | 2026-06-04 | Buy |
| Biosynth | FM139560 | Methyl 3-aminopicolinate | 36052-27-4 | 25g | $942.25 | 2026-06-04 | Buy |
| Biosynth | FM139560 | Methyl 3-aminopicolinate | 36052-27-4 | 50g | $1570.5 | 2026-06-04 | Buy |
3-Aminopyridine-2-carboxylic acid methyl ester Chemical Properties,Uses,Production
Uses
3-Aminopyridine-2-carboxylic acid methyl ester can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthesis
To a solution of 3-aminopyridine-2-carboxylic acid (20 g, 144.9 mmol) in methanol (300 mL) was added conc. sulfuric acid (5.4 mL), and the mixture was heated under reflux for 5 days. The reaction mixture was concentrated under reduced pressure, water was added thereto, and sodium carbonate was added thereto until the complete of foaming. The mixture was extracted with dichloromethane (x3), the organic layer was dried over sodium sulfate, and the solvent was evaporated under reduced pressure to give methyl 3-aminopyridine-2-carboxylate (17.0 g, 77%) as a pale yellow solid. 1H-NMR(300MHz,CDCl3):|3.95(3H,s),5.72(2H,brs),7.03(1H,dd,J=0.99,8. 35Hz),7.18-7.21(1H,m),8.05(1H,dd,J=0.96,4.04Hz).
References
[1] Patent: EP2975031, 2016, A1. Location in patent: Paragraph 1070
[2] Patent: WO2005/49613, 2005, A1. Location in patent: Page/Page column 39
[3] Patent: US2017/190713, 2017, A1. Location in patent: Paragraph 0260
[4] Patent: US2015/51395, 2015, A1. Location in patent: Paragraph 1163-1164
[5] Chemical Communications, 2016, vol. 52, # 59, p. 9283 - 9286
3-Aminopyridine-2-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Huaxing Biological Technology Co., Ltd. | 18621295758; 18621295758 | 1449085402@qq.com | China | 1973 | 55 |
| Shandong Baiqi Biomedical Co. Ltd | 0536-8998390 13173160180 | sales@baiqpharm.com | China | 581 | 58 |
| Nanbu County Chengxin Technology Co., Ltd. | 0838-5675166 15883665058 | nbcxkj@126.com | China | 956 | 55 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
View Lastest Price from 3-Aminopyridine-2-carboxylic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 3-Aminopyridine-2-carboxylic acid methyl ester
36052-27-4
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-09 | 3-Aminopyridine-2-carboxylic acid methyl ester
36052-27-4
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 3-Aminopyridine-2-carboxylic acid methyl ester
36052-27-4
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-Aminopyridine-2-carboxylic acid methyl ester
36052-27-4
- $3.00
- 98%
- Career Henan Chemical Co
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