3-[4-(Trifluoromethoxy)phenyl]acrylic acid
![3-[4-(Trifluoromethoxy)phenyl]acrylic acid Structure](CAS/GIF/783-13-1.gif)
- CAS No.
- 783-13-1
- Chemical Name:
- 3-[4-(Trifluoromethoxy)phenyl]acrylic acid
- Synonyms
- RARECHEM BK HW 0215;TIMTEC-BB SBB002369;4-(Trifluoromethoxy)Cinamic Acid;4-(TRIFLUOROMETHOXY)CINNAMIC ACID;p-(Trifluoromethoxyl)cinnamic acid;4-(Trifluoromethoxy)cinnamicacid96%;3-(4-(Trifluoromethoxy)phenyl)acrylicaci;3-[4-(TRIFLUOROMETHOXY)PHENYL]ACRYLIC ACID;3-(4-Trifluoromethoxyphenyl)-2-propenoic acid;(E)-3-[4-(trifluoromethoxy)phenyl]-2-propenoate
- CBNumber:
- CB1697335
- Molecular Formula:
- C10H7F3O3
- Molecular Weight:
- 232.16
- MDL Number:
- MFCD00066338
- MOL File:
- 783-13-1.mol
- MSDS File:
- SDS
| Melting point | 178 °C |
|---|---|
| Boiling point | 296.6±35.0 °C(Predicted) |
| Density | 1.403±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | 4.29±0.10(Predicted) |
| color | beige |
| InChI | InChI=1S/C10H7F3O3/c11-10(12,13)16-8-4-1-7(2-5-8)3-6-9(14)15/h1-6H,(H,14,15) |
| InChIKey | RNYVTJANWYBGPW-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C=CC1=CC=C(OC(F)(F)F)C=C1 |
| CAS DataBase Reference | 783-13-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-22 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2918999090 | |||||||||
| NFPA 704 |
|
3-[4-(Trifluoromethoxy)phenyl]acrylic acid price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC2756 | 4-(Trifluoromethoxy)cinnamic acid 97% | 783-13-1 | 1g | $28 | 2026-06-04 | Buy |
| Activate Scientific | AS25764 | 4-(Trifluoromethoxy)cinnamic Acid 98% | 783-13-1 | 1g | $29 | 2026-06-04 | Buy |
| Activate Scientific | AS25764 | 4-(Trifluoromethoxy)cinnamic Acid 98% | 783-13-1 | 5g | $84 | 2026-06-04 | Buy |
| Activate Scientific | AS25764 | 4-(Trifluoromethoxy)cinnamic Acid 98% | 783-13-1 | 25g | $220 | 2026-06-04 | Buy |
| Activate Scientific | AS25764 | 4-(Trifluoromethoxy)cinnamic Acid 98% | 783-13-1 | 100g | $548 | 2026-06-04 | Buy |
3-[4-(Trifluoromethoxy)phenyl]acrylic acid Chemical Properties, Uses, Production
Synthesis
141-82-2
659-28-9
![3-[4-(Trifluoromethoxy)phenyl]acrylic acid](/CAS/GIF/783-13-1.gif)
783-13-1
GENERAL STEPS: A mixture of 5.00 g (3.80 mL, 26.3 mmol) of 4-trifluoromethoxybenzaldehyde, 3.10 g (30.0 mmol) of malonic acid, 0.26 g (3.0 mmol) of piperidine, and 15.0 mL of pyridine was heated to reflux until carbon dioxide gas ceased to be produced (approximately 3 hours). Upon completion of the reaction, the mixture was cooled to room temperature and subsequently poured into a mixture consisting of 50 g of ice and 15 mL of 6N HCl. The precipitated solid was separated by filtration, washed with water and dried to give 5.20 g (85% yield) of 3-(4-trifluoromethoxyphenyl)acrylic acid. The product was characterized by 1H-NMR (400 MHz, D6-DMSO): δ = 6.57 (d, 1H, 2-H), 7.40 (d, 2H, 3'-/5'-H), 7.62 (d, 1H, 3-H), 7.84 (d, 2H, 2'-/6'-H), 12.5 (br, 1H, COOH).
References
[1] Patent: WO2004/85434, 2004, A1. Location in patent: Page 15
[2] Patent: US2005/209290, 2005, A1. Location in patent: Page/Page column 11
[3] Patent: US2005/267179, 2005, A1. Location in patent: Page/Page column 12
[4] Patent: US2007/259936, 2007, A1. Location in patent: Page/Page column 162
3-[4-(Trifluoromethoxy)phenyl]acrylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6742 | 52 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9739 | 58 |
View Latest Price from 3-[4-(Trifluoromethoxy)phenyl]acrylic acid manufacturers
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![3-[4-(Trifluoromethoxy)phenyl]acrylic acid pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/da49c536-f177-427d-b730-b09572147f64.png) |
2019-12-26 | 3-[4-(Trifluoromethoxy)phenyl]acrylic acid
783-13-1
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 3-[4-(Trifluoromethoxy)phenyl]acrylic acid
783-13-1
- $1.00
- 99%
- Career Henan Chemical Co
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