4-(Naphthalen-2-yl)phenylboronic acid
- CAS No.
- 918655-03-5
- Chemical Name:
- 4-(Naphthalen-2-yl)phenylboronic acid
- Synonyms
- 4-(2-Naphthyl)phenylboronic;CAS:918655-03-5;4-(2-naphthy)phenylboronic;4-(2-phthyl)phenylboronic acid;4-(2-Napthyl)phenylboronic acid;4-(2-Naphthy)phenylboronic acid;4-(naphthalen-2-yl)phenylboronic;4-(2-Naphthyl)benzeneboronic acid;4-(Naphthalen-2-YL)PhenylboronicAci;4-(2-naphthalenyl)phenylboronic acid
- CBNumber:
- CB21118830
- Molecular Formula:
- C16H13BO2
- Molecular Weight:
- 248.08
- MDL Number:
- MFCD09260454
- MOL File:
- 918655-03-5.mol
- MSDS File:
- SDS
| Boiling point | 463.0±48.0 °C(Predicted) |
|---|---|
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 8.58±0.16(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| InChI | InChI=1S/C16H13BO2/c18-17(19)16-9-7-13(8-10-16)15-6-5-12-3-1-2-4-14(12)11-15/h1-11,18-19H |
| InChIKey | ICQAKBYFBIWELX-UHFFFAOYSA-N |
| SMILES | B(C1=CC=C(C2=CC=C3C(=C2)C=CC=C3)C=C1)(O)O |
| CAS DataBase Reference | 918655-03-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 29319000 | |||||||||
| NFPA 704 |
|
4-(Naphthalen-2-yl)phenylboronic acid price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | N0946 | 4-(2-Naphthyl)phenylboronic Acid (contains varying amounts of Anhydride) | 918655-03-5 | 200mg | $23 | 2026-04-30 | Buy |
| TCI Chemical | N0946 | 4-(2-Naphthyl)phenylboronic Acid (contains varying amounts of Anhydride) | 918655-03-5 | 1g | $66 | 2026-04-30 | Buy |
| Activate Scientific | AS32804 | 4-(Naphthalen-2-yl)phenylboronic acid 97% | 918655-03-5 | 1g | $36 | 2026-06-04 | Buy |
| Activate Scientific | AS32804 | 4-(Naphthalen-2-yl)phenylboronic acid 97% | 918655-03-5 | 5g | $91 | 2026-06-04 | Buy |
| Matrix Scientific | 075165 | 4-(Naphthalen-2-yl)phenylboronic acid | 918655-03-5 | 1.00g | $69 | 2026-05-18 | Buy |
4-(Naphthalen-2-yl)phenylboronic acid Chemical Properties, Uses, Production
Uses
4-(naphthalene-2-)phenylboronic acid, as a recognizer of polyhydroxy compounds, is widely used in biomedical fields such as hydrogels, sensors, and cancer treatment.
Chemical Properties
white powder
Synthesis
22082-99-1
918655-03-5
Under argon protection, 50.0 g (177 mmol) of 4-(2-naphthalene)bromobenzene was mixed with 500 mL of anhydrous tetrahydrofuran (THF) and cooled to -60 °C. Subsequently, 136 mL (212 mmol) of a hexane solution of 1.56 M n-butyllithium was pre-cooled to -60 °C and slowly added dropwise to the reaction mixture under stirring. After the dropwise addition was completed, the reaction mixture continued to be stirred at -60 °C for 1 hour. Next, 99.6 g (529 mmol) of triisopropyl borate was slowly added dropwise at the same temperature. After completion of the dropwise addition, the reaction mixture was gradually warmed to room temperature and stirred continuously for 18 hours. After completion of the reaction, aqueous hydrochloric acid was added to the mixture and stirred for 1 hour at room temperature. After that, toluene was added for extraction and the aqueous phase was separated and discarded. The organic phase was dried with magnesium sulfate and concentrated under reduced pressure to remove the solvent. Finally, the resulting solid was purified by recrystallization from toluene to give 33.6 g of (4-(naphthalen-2-yl)phenyl)boronic acid in 84% yield.
References
[1] Patent: US2010/331585, 2010, A1. Location in patent: Page/Page column 95
[2] Patent: WO2007/86695, 2007, A1. Location in patent: Page/Page column 64
[3] Patent: KR2017/49296, 2017, A
4-(Naphthalen-2-yl)phenylboronic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BEIJING ODYSSEY CHEMICALS CO.,LTD | 010-88018188-305 13601004222 | maxma@bj-odyssey.com | China | 21 | 58 |
| Puyang Huicheng Electronic Material Co. Ltd. | 0393-0393-8910800 15039333257 | info@huichengchem.com | China | 588 | 64 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 4-(Naphthalen-2-yl)phenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 4-(2-Naphthyl)phenylboronic acid
918655-03-5
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
![Boronic acid,B-[4-(2-naphthalenyl)phenyl]- pictures](/ProductImageEN/2021-11/Small/0ccb8a0f-909d-4d21-96af-3e465cdd754b.gif) |
2026-08-18 | Boronic acid,B-[4-(2-naphthalenyl)phenyl]-
918655-03-5
|
1KG | 98.00% | 150KG /month | Shanghai Daken Advanced Materials Co.,Ltd | ||
 |
2025-05-23 | 4-(2-Naphthyl)phenylboronic acid
918655-03-5
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- 4-(2-Naphthyl)phenylboronic acid
918655-03-5
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- Boronic acid,B-[4-(2-naphthalenyl)phenyl]-
918655-03-5
- $0.00
- 98.00%
- Shanghai Daken Advanced Materials Co.,Ltd
-
- 4-(2-Naphthyl)phenylboronic acid
918655-03-5
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
