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2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile

CAS No.
3335-45-3
Chemical Name:
2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
Synonyms
Compound Fr13783;3-Cyan-6-(2-thienyl)-4-trifluormethyl-2(1H)-pyridon;2-HYDROXY-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBONITRILE;2-HYDROXY-6-(THIEN-2-YL)-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBONITRILE;2-oxo-6-thiophen-2-yl-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile;2-Hydroxy-6-thien-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile97%;2-Hydroxy-6-thien-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile 97%;3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-6-(2-thienyl)-4-(trifluoromethyl)-;3-[4-(1-ethoxy-2-phenylethyl)-1-piperazinyl]-1-(4-methoxyphenyl)-1-propanol dihydrochloride
CBNumber:
CB2120685
Molecular Formula:
C11H5F3N2OS
Molecular Weight:
270.23
MDL Number:
MFCD00052654
MOL File:
3335-45-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:12

2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile Properties

Melting point 278°C
Boiling point 390.2±42.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
form solid
pka 5.78±0.10(Predicted)
Sensitive Stench
InChI 1S/C11H5F3N2OS/c12-11(13,14)7-4-8(9-2-1-3-18-9)16-10(17)6(7)5-15/h1-4H,(H,16,17)
InChIKey UBBGOCKMIMCHLZ-UHFFFAOYSA-N
SMILES Oc1nc(cc(c1C#N)C(F)(F)F)-c2cccs2
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H319
Precautionary statements  P301+P310+P330-P305+P351+P338
Hazard Codes  Xi,T
Risk Statements  36/37/38-36-25
Safety Statements  26-36/37/39-45
RIDADR  3439
WGK Germany  3
Hazard Note  Irritant/Stench
HS Code  2933399990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2

2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich JRD0368 2-Hydroxy-6-(2-thienyl)-4-trifluoromethyl nicotinonitrile Aldrich 3335-45-3 1g $77.9 2026-04-30 Buy
Apolloscientific PC4865 2-Hydroxy-6-(thien-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile ≥95% 3335-45-3 1g $75 2026-06-04 Buy
Apolloscientific PC4865 2-Hydroxy-6-(thien-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile ≥95% 3335-45-3 5g $198 2026-06-04 Buy
Apolloscientific PC4865 2-Hydroxy-6-(thien-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile ≥95% 3335-45-3 10g $347 2026-06-04 Buy
Matrix Scientific 088919 2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)-nicotinonitrile 3335-45-3 1.00g $91 2026-05-18 Buy
Product number Packaging Price Buy
JRD0368 1g $77.9 Buy
PC4865 1g $75 Buy
PC4865 5g $198 Buy
PC4865 10g $347 Buy
088919 1.00g $91 Buy

2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile Chemical Properties,Uses,Production

Definition

ChEBI: 2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile is a nitrile and a member of pyridines.

326-91-0
107-91-5
3335-45-3
Synthesis of 2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile from Thenoyltrifluoroacetone and 2-Cyanoacetamide

2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

2-Hydroxy-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
2-Hydroxy-6-thien-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile 97% 2-Hydroxy-6-thien-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile97% 2-oxo-6-thiophen-2-yl-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile 2-HYDROXY-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBONITRILE 2-HYDROXY-6-(THIEN-2-YL)-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBONITRILE 3-Cyan-6-(2-thienyl)-4-trifluormethyl-2(1H)-pyridon 3-[4-(1-ethoxy-2-phenylethyl)-1-piperazinyl]-1-(4-methoxyphenyl)-1-propanol dihydrochloride 3-Pyridinecarbonitrile, 1,2-dihydro-2-oxo-6-(2-thienyl)-4-(trifluoromethyl)- Compound Fr13783 3335-45-3