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FMOC-S-trityl-L-cysteine

FMOC-S-trityl-L-cysteine Structure
FMOC-S-trityl-L-cysteine structure
CAS No.
103213-32-7
Chemical Name:
FMOC-S-trityl-L-cysteine
Synonyms
FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;Fmoc-Cys(Trt)-OH Fmoc-Cys(Trt)-OH;N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-S-(TRIPHENYLMETHYL)-L-CYSTEINE
CBNumber:
CB2138770
Molecular Formula:
C37H31NO4S
Molecular Weight:
585.71
MDL Number:
MFCD00038538
MOL File:
103213-32-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:42:22
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FMOC-S-trityl-L-cysteine Properties

Melting point 170-173 °C(lit.)
alpha 16 º (c=1, THF)
Boiling point 763.4±60.0 °C(Predicted)
Density 1.270±0.06 g/cm3(Predicted)
refractive index 18 ° (C=1, THF)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 3.70±0.10(Predicted)
form Powder
color White to almost white
optical activity [α]20/D +16.0±2°, c = 1% in THF
Water Solubility Insoluble in water. Soluble in most organic solvents.
BRN 4221286
Major Application peptide synthesis
InChIKey KLBPUVPNPAJWHZ-UMSFTDKQSA-N
SMILES OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
CAS DataBase Reference 103213-32-7(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-26
WGK Germany  3
F  9-21
Hazard Note  Irritant
HS Code  29309090
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
0 0

FMOC-S-trityl-L-cysteine price More Price(121)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 25g $94.8 2026-04-30 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 100g $232 2026-04-30 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 250g $501 2026-04-30 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem® 103213-32-7 500 g $919 2026-04-30 Buy
Sigma-Aldrich 8.52008 Fmoc-Cys(Trt)-OH Novabiochem? 103213-32-7 1kg $1650 2026-04-30 Buy
Product number Packaging Price Buy
8.52008 25g $94.8 Buy
8.52008 100g $232 Buy
8.52008 250g $501 Buy
8.52008 500 g $919 Buy
8.52008 1kg $1650 Buy

FMOC-S-trityl-L-cysteine Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:

  • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
  • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
  • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

Uses

FMOC-S-trityl-L-cysteine is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. The compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-S-trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

9H-Fluoren-9-ylmethylN-[(1R)-1-[methoxy(methyl)carbamoyl]-2-[(triphenylmethyl)sulfanyl]ethyl]carbamate

FMOC-S-trityl-L-cysteine Suppliers

Global Suppliers ( 538)
Supplier Tel Email Country ProdList Advantage
Lanxi Xingnuo Import and Export Trading Co., Ltd 0579-8831088 15888978871 994350525@qq.com China 23 58
Jiangsu Jitai Peptide Technology Co., Ltd. 051580855066 13770132022 sales05@gtaipeptide.com China 2675 58
Gill polypeptide biopharmaceutical (dalian) co., LTD 021-61263455 13167021076 amy@glschina.com China 9699 58
Chengdu Tachem Co., Ltd 028-61682518; 19983060238 sales@tachem.cn China 102 58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD 0838-2809458 13350585791 pharm@biots.cn China 778 58
Chengdu ZY Biochemical Technology Co., Ltd. 88680086 13398185735 fengzilong@zybiochem.com China 177 58
Shanghai Qihong Pharmaceutical Technology Co., Ltd. 13482681346 18117455885 qihongchem@163.com China 8731 58
Wuhan Grand Hoyo Co., Ltd. 15377006636 670196467@qq.com China 31 58
Zhangjiagang Specom Biochemical Co., Ltd. 512-0512-58992291,58992287 18606280718 admin@spbiochem.com China 306 62
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Supplier Advantage
Lanxi Xingnuo Import and Export Trading Co., Ltd 58
Jiangsu Jitai Peptide Technology Co., Ltd. 58
Gill polypeptide biopharmaceutical (dalian) co., LTD 58
Chengdu Tachem Co., Ltd 58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD 58
Chengdu ZY Biochemical Technology Co., Ltd. 58
Shanghai Qihong Pharmaceutical Technology Co., Ltd. 58
Wuhan Grand Hoyo Co., Ltd. 58
Zhangjiagang Specom Biochemical Co., Ltd. 62
J & K SCIENTIFIC LTD. 76

View Latest Price from FMOC-S-trityl-L-cysteine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-Cys(Trt)-OH pictures 2026-09-18 Fmoc-Cys(Trt)-OH
103213-32-7
 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
FMOC-S-trityl-L-cysteine pictures 2026-09-18 FMOC-S-trityl-L-cysteine
103213-32-7
 1kg 99% 200mt/year Jinan Finer Chemical Co., Ltd
Fmoc-L-Cys(trt)-OH pictures 2026-09-17 Fmoc-L-Cys(trt)-OH
103213-32-7
 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd

FMOC-S-trityl-L-cysteine Spectrum

FMOC-S-trityl-L-cysteine(103213-32-7)1HNMR

103213-32-7 (FMOC-S-trityl-L-cysteine) Related Search:

6-Aminocaproic acid L-Fmoc-Aspartic acid alpha-tert-butyl ester L-Cysteine Trityl candesartan cilexetil Trityl Irbesartan
Fmoc-Lys(Boc)-OH Triphenylmethyl Chloride Fmoc-Phe-OH p-Toluenesulfonic acid 9-Fluorenylmethyl chloroformate
Propionic acid Fmoc-OSu Glycine Aminoethoxyvinyl glycine hydrochloride Carbonyl sulfide
Pyrazophos Methoxycarbonylsulfenyl chloride Tris(hydroxymethyl)aminomethane

1of4

FMOC-CYSTEINE(TRT)-OH FMOC-L-CYSTEINE(TRITYL) FMOC-L-CYSTEINE (TRT) FMOC-L-CYS(TRITYL) FMOC-S-TRITYL-L-CYSTEINE 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID L-CYSTEINE-N-FMOC, S-TRITYL 9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE N-FMOC-L-CYS(TRT)-OH (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID FMoc-Cys(Trt)-OH FMoc-S-trityl-L-cysteine N-Fmoc-S-trityl-L-cysteine Fmoc-Cys(Trt)-OH (R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tritylthio)propanoic acid (R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-(tritylthio)propan-2-yl)carbamate Fmoc-Cys(Trt)-OH >=95.0% (sum of enantiomers, HPLC) Fmoc-Cys(Trt)-OH, >=99% (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Non-Animal Origin) (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Animal Origin) (R)-2-Fmoc-3-tritylsulfanyl-propionic acid Fmoc-S-trityl-L-cysteine≥ 99.7% (HPLC, Chiral purity) Fmoc-Cys(Trt)-OH(Animal origin) Fmoc-Cys(Trt)-OH(Non-Animal origin) (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[(triphenylmethyl)thio]propanoate n-(alpha)-fluorenylmethyloxycarbonyl-s-tritylcysteine Nα-Fmoc-S-trityl-L-cysteine N-(9-FLUORENYLMETHOXYCARBONYL)-S- FMOC-CYS(TRT)-OH, 98+% N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cystei L-Cysteine-3,3-D2-N-FMOC-S-Trityl L-Cysteine-N-FMOC-UL-13C3, 15N, S-Trityl FMOC-S-TRITYL-L-CYSTEINE (FMOC-L-CYS(TRT)-OH) (R)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)cysteine (9-fluorenylmethoxycarbonyl)-L-cysteine (trityl) N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine Nα-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine ,98% N-[(9H-Fluoren-9-yloxy)carbonyl]-S-trityl-L-cysteine FMOC-S-trityl-L-Cysteine,97% Nα-Fmoc-S-trityl-L-c S-Trityl-N-Fomc_L-Cysteine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine> FMOC-CYS(TRT)-OH 25 G FMOC-CYS(TRT)-OH 100 G FMOC-CYS(TRT)-OH 250 G L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)- Fmoc-Cys(Trt)-OH(animal) FMOC-S-trityl-L-cysteine USP/EP/BP (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid FMOC-S-trChemicalbookityl-L-cysteine Nα-Fmoc-S-trityl-L-cysteine N-FMOC-S-(Triphenylmethyl)-L-cysteine Fmoc-S-triphenylmethyl-L-cysteine