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Boc-Tyr-OtBu

Boc-Tyr-OtBu Structure
Boc-Tyr-OtBu structure
CAS No.
18938-60-8
Chemical Name:
Boc-Tyr-OtBu
Synonyms
Boc-L-Tyr-OtBu;Boc-Tyr-OtBu;Boc-Tyr-Otbu-OH;(Tert-Butoxy)Carbonyl Tyr-OtBu;Boc-L-tyrosine tert-butyl ester;N-Boc-L-tyrosine tert-Butyl Ester;N-[ tert-butoxycarbonyl ]-L- tyrosine tert-butyl ester;N-[(1,1-Dimethylethoxy)carbonyl]-L-tyrosine 1,1-dimethylethyl ester;L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester;tert-butyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate
CBNumber:
CB21456688
Molecular Formula:
C18H27NO5
Molecular Weight:
337.41
MDL Number:
MFCD20264826
MOL File:
18938-60-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:55:58
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Boc-Tyr-OtBu Properties

Melting point 111-112 °C(Solv: ligroine (8032-32-4); ethyl acetate (141-78-6))
Boiling point 476.0±40.0 °C(Predicted)
Density 1.117±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form Solid
pka 9.75±0.15(Predicted)
color White to off-white
optical activity Consistent with structure

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H350
Precautionary statements  P501-P202-P201-P280-P308+P313-P405

Boc-Tyr-OtBu price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemPep 111904-25G Boc-Tyr-OtBu 25g $300 2026-06-04 Buy
ChemPep 111904-100G Boc-Tyr-OtBu 100g $750 2026-06-04 Buy
ChemScene CS-0030789 Boc-Tyr-OtBu ≥98% 18938-60-8 5g $10 2026-06-04 Buy
ChemScene CS-0030789 Boc-Tyr-OtBu ≥98% 18938-60-8 10g $13 2026-06-04 Buy
ChemScene CS-0030789 Boc-Tyr-OtBu ≥98% 18938-60-8 25g $28 2026-06-04 Buy
Product number Packaging Price Buy
111904-25G 25g $300 Buy
111904-100G 100g $750 Buy
CS-0030789 5g $10 Buy
CS-0030789 10g $13 Buy
CS-0030789 25g $28 Buy

Boc-Tyr-OtBu Chemical Properties, Uses, Production

Uses

Boc-Tyr-OtBu is a tyrosine derivative[1].

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

tert-Butyl L-tyrosinate

16874-12-7

Boc-Tyr-OtBu

18938-60-8

To a solution of 9.82 g (0.041 mol) tert-butyl L-tyrosinate in 150 mL of dichloromethane and 20 mL of DMF was added 5.2 g (0.04 mol) of triethylamine, followed by 9.03 g (0.04 mol) of di-tert-butyl dicarbonate. The reaction mixture was stirred at room temperature for 2 h. Upon completion of the reaction, it was washed sequentially with 1N HCl (3 × 50 mL), saturated NaHCO3 solution (1 × 50 mL), and brine (1 × 50 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated in vacuum to give 13.59 g (98% yield) of white solid product. The structure of the product was confirmed by 300 MHz 1H NMR (CDCl3): δ 1.42 (s, 18H), 2.95 (d, 2H), 4.39 (dd, 1H), 5.01 (d, 1H), 6.15 (s, 1H), 6.70 (d, 2H), 7.00 (d, 2H).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

Boc-Tyr-OtBu Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate tert-Butyl L-tyrosinate DMF ( N,N-dimethylformamide ) Dichloromethane Triethylamine

Preparation Products

BOC-L-Tyrosine

Boc-Tyr-OtBu Suppliers

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1997 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Beijing FYF Chemicals Co., Ltd 010-57903446 15869909019 168931144@qq.com China 2876 58
Sichuan Ampebiochem Co., Ltd. 028-65294243 18682730901 sales@ampebiochem.com China 1000 58
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8059 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Wuxi Asia Peptide Biotechnology Limited Company 0510-83583050 13771062561 willsun@peptide-search.com China 6713 58
Supplier Advantage
Energy Chemical 61
GL Biochem (Shanghai) Ltd 64
ChemPep, Inc. 57
Chengdu Forest Science and Technology Development Co., Ltd. 58
Bide Pharmatech Ltd. 60
Beijing FYF Chemicals Co., Ltd 58
Sichuan Ampebiochem Co., Ltd. 58
Shanghai GL Peptide Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Wuxi Asia Peptide Biotechnology Limited Company 58

View Latest Price from Boc-Tyr-OtBu manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Tyr-Otbu pictures 2026-09-17 Boc-Tyr-Otbu
18938-60-8
 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd
Boc-Tyr-OtBu pictures 2020-01-09 Boc-Tyr-OtBu
18938-60-8
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

Boc-Tyr-OtBu Spectrum

Boc-Tyr-OtBu(18938-60-8)1HNMR

18938-60-8 (Boc-Tyr-OtBu) Related Search:

Boc-Ser(Tos)-OCH3 Boc-D-Tyr(tBu)-OH Boc-DL-Pro-OH Boc-Trp(Boc)-OH L(+)-Arginine
L-Tryptophan 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol Methyl N-(tert-butoxycarbonyl)-L-threoninate N-Boc-4-oxo-L-Proline methyl ester Boc-D-Ser(tBu)-OH

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Boc-Tyr-OtBu (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propionic acid tert-butyl ester Boc-L-tyrosine tert-butyl ester N-[(1,1-Dimethylethoxy)carbonyl]-L-tyrosine 1,1-dimethylethyl ester L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester (Tert-Butoxy)Carbonyl Tyr-OtBu tert-butyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate N-Boc-L-tyrosine tert-Butyl Ester N-[ tert-butoxycarbonyl ]-L- tyrosine tert-butyl ester Boc-Tyr-Otbu-OH Boc-L-Tyr-OtBu 18938-60-8 18936-60-8