Boc-DL-Pro-OH
- CAS No.
- 59433-50-0
- Chemical Name:
- Boc-DL-Pro-OH
- Synonyms
- N-BOC-DL-PROLINE;1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID;NSC 108689;AKOS 91525;Boc-DL-Pro;Boc-DL-Pro-OH;BOC-DL-PROLINE;N-Boc-DL-proline,98%;REF DUPL: Boc-DL-Pro-OH;BOC-DL-PRO-OH USP/EP/BP
- CBNumber:
- CB4224035
- Molecular Formula:
- C10H17NO4
- Molecular Weight:
- 215.25
- MDL Number:
- MFCD00520915
- MOL File:
- 59433-50-0.mol
- MSDS File:
- SDS
| Melting point | 133-135°C |
|---|---|
| Boiling point | 337.2±35.0 °C(Predicted) |
| Density | 1.201±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 4.01±0.20(Predicted) |
| Appearance | White to off-white Powder |
| optical activity | Consistent with structure |
| InChI | InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13) |
| InChIKey | ZQEBQGAAWMOMAI-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CCCC1C(O)=O |
| CAS DataBase Reference | 59433-50-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
Boc-DL-Pro-OH price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4285 | Boc-DL-Pro-OH | 59433-50-0 | 5G | $66 | 2026-04-30 | Buy |
| TCI Chemical | B4285 | Boc-DL-Pro-OH | 59433-50-0 | 25G | $199 | 2026-04-30 | Buy |
| AstaTech | 53395 | N-BOC-DL-PROLINE 97% | 59433-50-0 | 50G | $29 | 2026-04-30 | Buy |
| ChemPep | 111503-5G | Boc-DL-Pro-OH | 5g | $110 | 2026-06-04 | Buy | |
| ChemPep | 111503-25G | Boc-DL-Pro-OH | 25g | $226 | 2026-06-04 | Buy |
Boc-DL-Pro-OH Chemical Properties, Uses, Production
Uses
(±)-N-(tert-Butoxycarbonyl)proline is a useful reagent for the enantiospecific preparation of functionalized hindered triazolopyridinones.
Synthesis
To a 100 ml round bottom flask was added L-proline 1a (3.0 g, 26.06 mmol), sodium hydroxide (1.2 g, 28.66 mmol) and tert-butanol/water (20 ml/20 ml), respectively. Di-tert-butyl dicarbonate (6.3 g, 28.66 mmol) was slowly added to the reaction system under stirring at 0C cooling and the temperature was then slowly raised to room temperature. After the end of the reaction was detected by TLC, the tert-butanol was removed by spinning under reduced pressure to obtain the crude product in the aqueous phase, which was washed three times with petroleum ether (3x 30 ml), after which it was adjusted to pH = 6 with 1N hydrochloric acid and extracted with ethyl acetate (3x 50 ml). The combined ethyl acetate extracts were dried over anhydrous sodium sulfate and the solvent was removed by spinning under reduced pressure to give a white solid pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (5.49 g, 98% yield).
Boc-DL-Pro-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Dexinjia Biopharm Co., Ltd | 0531-82375893 15553111391 | phoebe@jndxj.com | China | 285 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from Boc-DL-Pro-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | Boc-DL-Pro-OH
59433-50-0
|
1kg | 98% | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-07-30 | BOC-DL-Proline
59433-50-0
|
$200.00 | 1KG | 98% | 20TONS | Anhui Dexinjia Biopharm Co., Ltd | |
 |
2019-08-08 | 6-FLUOROURACIL
59433-50-0
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Boc-DL-Pro-OH
59433-50-0
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- BOC-DL-Proline
59433-50-0
- $200.00
- 98%
- Anhui Dexinjia Biopharm Co., Ltd
-
- 6-FLUOROURACIL
59433-50-0
- $3.00
- 99%
- Career Henan Chemical Co
