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N-Fmoc-8-Aminooctanoic acid

CAS No.
126631-93-4
Chemical Name:
N-Fmoc-8-Aminooctanoic acid
Synonyms
FMOC-8-AOC-OH;FMOC-8-AMINOOCTANOIC ACID;FMOC-8-AMINOCAPRYLIC ACID;FMOC-AOC(8)-OH;FMOC-NH-(CH2)7-COOH;RARECHEM EM WB 0026;FMOC-AMINOCAPRYLIC ACID;N-Fmoc-8-Aminooctanoicaci;Fmoc-8-Aoc-OH, ≥98% (HPLC);N-FMOC-8-AMINOOCTANOIC ACID
CBNumber:
CB2145853
Molecular Formula:
C23H27NO4
Molecular Weight:
381.46
MDL Number:
MFCD00235890
MOL File:
126631-93-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:56:48

N-Fmoc-8-Aminooctanoic acid Properties

Melting point 118-119 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
Boiling point 597.7±33.0 °C(Predicted)
Density 1.174±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form Powder
pka 4.77±0.10(Predicted)
color White
BRN 8286497
Major Application peptide synthesis
InChI 1S/C23H27NO4/c25-22(26)14-4-2-1-3-9-15-24-23(27)28-16-21-19-12-7-5-10-17(19)18-11-6-8-13-20(18)21/h5-8,10-13,21H,1-4,9,14-16H2,(H,24,27)(H,25,26)
InChIKey QZQXRZXYWVQWAY-UHFFFAOYSA-N
SMILES OC(=O)CCCCCCCNC(=O)OCC1c2ccccc2-c3ccccc13
CAS DataBase Reference 126631-93-4(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29242990
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

N-Fmoc-8-Aminooctanoic acid price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 47998 Fmoc-8-Aoc-OH ≥98.0% (HPLC) 126631-93-4 500mg $185 2026-04-30 Buy
Usbiological 277132 Fmoc-8-aminocaprylic acid Asreported 126631-93-4 1g $366 2026-06-03 Buy
Usbiological 277132 Fmoc-8-aminocaprylic acid Asreported 126631-93-4 2g $508 2026-06-03 Buy
Usbiological 277132 Fmoc-8-aminocaprylic acid Asreported 126631-93-4 5g $909 2026-06-03 Buy
Usbiological 277132 Fmoc-8-aminocaprylic acid Asreported 126631-93-4 10g $1293 2026-06-03 Buy
Product number Packaging Price Buy
47998 500mg $185 Buy
277132 1g $366 Buy
277132 2g $508 Buy
277132 5g $909 Buy
277132 10g $1293 Buy

N-Fmoc-8-Aminooctanoic acid Chemical Properties, Uses, Production

Description

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

N-Fmoc-8-Aminooctanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 148)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 45000 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16307 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Wuxi Zhangkun Biochemical Technology Co., Ltd. +86 0510-85629785 China 2321 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

View Latest Price from N-Fmoc-8-Aminooctanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Fmoc-8-aminooctanoic acid pictures 2026-05-11 N-Fmoc-8-aminooctanoic acid
126631-93-4
$1520.00-2500.00 10g TargetMol Chemicals Inc.
N-Fmoc-8-Aminooctanoic acid pictures 2025-06-27 N-Fmoc-8-Aminooctanoic acid
126631-93-4
$10.00-30.00 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
N-Fmoc-8-Aminooctanoic acid pictures 2025-06-20 N-Fmoc-8-Aminooctanoic acid
126631-93-4
1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.

N-Fmoc-8-Aminooctanoic acid Spectrum

N-FMOC-8-AMINOOCTANOIC ACID N-(9-FLUORENYLMETHYLOXYCARBONYL)-8-AMINO-OCTANOIC ACID N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOCAPRYLIC ACID N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOOCTANOIC ACID N-ALPHA-FMOC-8-AMINOOCTANOIC ACID RARECHEM EM WB 0026 FMOC-NH-(CH2)7-COOH FMOC-AOC(8)-OH FMOC-AMINOCAPRYLIC ACID FMOC-8-AMINOCAPRYLIC ACID NALPHA-9-Fluorenylmethoxycarbonyl-8-aminooctanoic acid Fmoc-omega-aminocaprylic acid Fmoc-8-aminooctanoic acid (Fmoc-aminocaprylic acid) 8-Aminooctanoic acid, N-FMOC protected 8-(Fmoc-amino)caprylic acid, 8-(Fmoc-amino)octanoic acid 8-(9H-Fluoren-9-ylmethoxycarbonylamino)octanoic acid 8-(FMOC-AMINO)CAPRYLIC ACID 8-(FMOC-AMINO)OCTANOIC ACID FMoc-8-Aoc-OH, FMoc-o-aMinocaprylic acid FMoc-8-Aoc-OH >=98.0% (HPLC) Fmoc-8-aminocaprylic acid≥ 99% (HPLC) Octanoic acid,8-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]- (9H-Fluoren-9-yl)MethOxy]Carbonyl 8-Aoc-OH 8-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]octanoic acid N-Fmoc-8-Aminooctanoicaci N-Fmoc-8-Aminooctanoic acid USP/EP/BP Fmoc-8-Aoc-OH, ≥98% (HPLC) 8-[N-FMOC-Amino]octanoic acid N-Fmoc-8-Aminooctanoic acid (Standard) FMOC-8-AMINOOCTANOIC ACID FMOC-8-AOC-OH 126631-93-4 amino Amino Acids