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(Fmoc-Cys-OH)2

(Fmoc-Cys-OH)2 Structure
(Fmoc-Cys-OH)2 structure
CAS No.
135273-01-7
Chemical Name:
(Fmoc-Cys-OH)2
Synonyms
(2R,2'R)-3,3'-Disulfanediylbis(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid);(FMOC-CYS)2;Fmoc-L-Cystin;Fmoc-L-Cystine;(Fmoc-Cys-OH)2;(Fmoc-L-Cys-OH)2;N,N'-Bis-FMoc-L-cystine;(Fmoc-Cys-OH)2 (Disulfide bond);N-ALPHA,N-ALPHA-BIS-FMOC-L-CYSTINE;Nα,Nα-Bis-Fmoc-L-cystine(Disulfide bond)
CBNumber:
CB2283906
Molecular Formula:
C36H32N2O8S2
Molecular Weight:
684.78
MDL Number:
MFCD00237447
MOL File:
135273-01-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:37
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(Fmoc-Cys-OH)2 Properties

Melting point 189-201 °C
Boiling point 925.8±65.0 °C(Predicted)
Density 1.412
Flash point 513.7℃
storage temp. Sealed in dry,2-8°C
pka 3.06±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
HS Code  29309090

(Fmoc-Cys-OH)2 price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264846 N-alpha,N-alpha-Bis-Fmoc-L-cystine(Disulfide bond) Asreported 135273-01-7 1g $373 2026-06-03 Buy
Usbiological 264846 N-alpha,N-alpha-Bis-Fmoc-L-cystine(Disulfide bond) Asreported 135273-01-7 2g $519 2026-06-03 Buy
Usbiological 264846 N-alpha,N-alpha-Bis-Fmoc-L-cystine(Disulfide bond) Asreported 135273-01-7 5g $882 2026-06-03 Buy
Usbiological 264846 N-alpha,N-alpha-Bis-Fmoc-L-cystine(Disulfide bond) Asreported 135273-01-7 10g $1250 2026-06-03 Buy
Usbiological 264846 N-alpha,N-alpha-Bis-Fmoc-L-cystine(Disulfide bond) Asreported 135273-01-7 25g $1795 2026-06-03 Buy
Product number Packaging Price Buy
264846 1g $373 Buy
264846 2g $519 Buy
264846 5g $882 Buy
264846 10g $1250 Buy
264846 25g $1795 Buy

(Fmoc-Cys-OH)2 Chemical Properties, Uses, Production

Chemical Properties

White to off-white powder

Synthesis

L-Cystine

56-89-3

9-Fluorenylmethyl chloroformate

28920-43-6

(FMOC-CYS-OH)2

135273-01-7

The general procedure for the synthesis of Fmoc-L-cystine from L-cystine and 9-fluorenylmethyl chloroformate was as follows: sodium carbonate (4.6 g, 43.6 mmol) and L-cystine (5.0 g, 20.8 mmol) were dissolved in deionized water (200 mL). The reaction system was cooled to 10 °C. Methyl 9-fluorenyl chloroformate (Fmoc-Cl, 11.85 g, 45.8 mmol) was dissolved in 1,4-dioxane (80 mL) and this solution was slowly added dropwise to the above aqueous L-cystine solution. The reaction mixture was stirred continuously at 10 °C for 2 h, followed by natural warming to room temperature. Upon completion of the reaction, a thick white precipitate was produced, which was drained through a sintered glass funnel. The resulting solid was washed with ether (50 mL) and ground, followed by drying under vacuum for 48 hours. The final N,N'-bis(Fmoc)-L-cystine (14.0 g, 98% yield) was obtained as a white powdery product.

References

[1] Patent: US2007/37963, 2007, A1. Location in patent: Page/Page column 11-12; Figure 4

(Fmoc-Cys-OH)2 Preparation Products And Raw materials

Raw materials

L-Cystine Fmoc-OSu 9-Fluorenylmethyl chloroformate Water 1,4-Dioxane
Sodium carbonate

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Preparation Products

Fmoc-Cys(tBu)-OH Fmoc-Cys(StBu)-OH

(Fmoc-Cys-OH)2 Suppliers

Global Suppliers ( 68)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai GL Peptide Ltd. +86-21-61263310 13764994101 fisherwang@glschina.com China 8059 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky (shanghai) International Co.,Ltd 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Amatek Scientific Co. Ltd. 55
Bide Pharmatech Ltd. 60
Cool Pharm, Ltd 58
Shanghai GL Peptide Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Latest Price from (Fmoc-Cys-OH)2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(Fmoc-Cys-OH)2 pictures 2026-09-16 (Fmoc-Cys-OH)2
135273-01-7
 1kg 98% 1T Sichuan HongRi Pharma-Tech Co.,Ltd

135273-01-7 ((Fmoc-Cys-OH)2) Related Search:

3,3'-Dithiodipropionic acid (Fmoc-Cys-OSu)2, (Disulfide bond) (Fmoc-Cys-OH)2 (Fmoc-Cys-OtBu)2, (disulfide bond) Fmoc-Lys-OH
(Boc-Cys-OH)2

1of2

(FMOC-CYS)2 N-ALPHA,N-ALPHA-BIS-FMOC-L-CYSTINE N,N'-DI-9-FLUORENYLMETHOXYCARBONYL-L-CYSTINE (Fmoc-Cys-OH)2 (Disulfide bond) Nα,Nα-Bis-FMoc-L-cystine N,N'-Bis-FMoc-L-cystine Nalpha,Nalpha-Bis-Fmoc-L-cystine(Disulfide bond) (Fmoc-L-Cys-OH)2 Nα,Nα-Bis-Fmoc-L-cystine(Disulfide bond)≥ 99% (HPLC) ((9H-Fluoren-9-yl)MethOxy]Carbonyl Cys-OH)2 (2R)-3-{[(2R)-2-carboxy-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]disulfanyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid L-Cystine, N,N'-bis[(9H-fluoren-9-ylmethoxy)carbonyl]- Nα,Nα-Bis-Fmoc-L-cystine(Disulfide bond) Fmoc-L-Cystine (2R,2'R)-3,3'-Disulfanediylbis(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid) Fmoc-L-Cystin (Fmoc-Cys-OH)2 135273-01-7 C36H32N2O8S2