ChemicalBook >> CAS DataBase List >>4-IODO-2-FLUORO-3-FORMYLPYRIDINE

4-IODO-2-FLUORO-3-FORMYLPYRIDINE

4-IODO-2-FLUORO-3-FORMYLPYRIDINE structure

CAS No.: 153034-82-3

Chemical Name:: 4-IODO-2-FLUORO-3-FORMYLPYRIDINE

Synonyms: 2-FLUORO-4-IODONICOTINALDEHYDE;2-fluoro-4-iodonicotaldehyde;2-FLUORO-3-FORMYL-4-IODOPYRIDINE;4-IODO-2-FLUORO-3-FORMYLPYRIDINE;2-fluoro-4-iodo3-aldehyde pyridine;2-Fluoro-4-iodopyridine-3-carbaldehyde;2 - F -3 - aldehyde -4 - iodine pyridine;2-Fluoro-4-iodo-3-pyridinecarboxaldehyde;2-FLUORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE;2-fluoro-4-iodo-3-pyridinecarboxyaldehyde

CBNumber:: CB2415952

Molecular Formula:: C6H3FINO

Molecular Weight:: 251

MDL Number:: MFCD03095290

MOL File:: 153034-82-3.mol

MSDS File:: SDS

Last updated:2026-06-10 19:52:18

Product description	Number	Pack Size	Price
2-Fluoro-3-formyl-4-iodopyridine	SYX00351	1g	$230
2-Fluoro-4-iodonicotinaldehyde ≥95%	PC8525	1g	$21
2-Fluoro-4-iodonicotinaldehyde ≥95%	PC8525	5g	$45
2-Fluoro-4-iodonicotinaldehyde ≥95%	PC8525	1g	$21
2-Fluoro-4-iodonicotinaldehyde ≥95%	PC8525	5g	$45
More product size

Request For Quotation

4-IODO-2-FLUORO-3-FORMYLPYRIDINE Properties

Boiling point	304.2±42.0 °C(Predicted)
Density	2.081±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form	solid
pka	-3.62±0.18(Predicted)
color	Yellow
InChI	InChI=1S/C6H3FINO/c7-6-4(3-10)5(8)1-2-9-6/h1-3H
InChIKey	VONGIOGTLFSXDE-UHFFFAOYSA-N
SMILES	C1(F)=NC=CC(I)=C1C=O
CAS DataBase Reference	153034-82-3(CAS DataBase Reference)
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi,Xn
Risk Statements	22
WGK Germany	WGK 3
Hazard Note	Irritant
HS Code	2933399990
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral

4-IODO-2-FLUORO-3-FORMYLPYRIDINE price More Price(60)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SYX00351	2-Fluoro-3-formyl-4-iodopyridine	153034-82-3	1g	$230	2026-04-30	Buy
Apolloscientific	PC8525	2-Fluoro-4-iodonicotinaldehyde ≥95%	153034-82-3	1g	$21	2026-06-04	Buy
Apolloscientific	PC8525	2-Fluoro-4-iodonicotinaldehyde ≥95%	153034-82-3	5g	$45	2026-06-04	Buy
Apolloscientific	PC8525	2-Fluoro-4-iodonicotinaldehyde ≥95%	153034-82-3	1g	$21	2026-06-04	Buy
Apolloscientific	PC8525	2-Fluoro-4-iodonicotinaldehyde ≥95%	153034-82-3	5g	$45	2026-06-04	Buy

Product number	Packaging	Price	Buy
SYX00351	1g	$230	Buy
PC8525	1g	$21	Buy
PC8525	5g	$45	Buy
PC8525	1g	$21	Buy
PC8525	5g	$45	Buy

4-IODO-2-FLUORO-3-FORMYLPYRIDINE Chemical Properties,Uses,Production

Application

2-Fluoro-3-aldehyde-4-iodopyridine is a heterocyclic organic compound that can be used as a pharmaceutical synthesis intermediate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 7832, 1993 DOI: 10.1021/jo00079a031

Synthesis

113975-22-7

109-94-4

153034-82-3

To a solution of diisopropylamine (174.4 g, 1.73 mol) in anhydrous THF (3 L) was added slowly and dropwise 2.5 M hexane solution of n-butyllithium (n-BuLi) (685 mL, 1.71 mol) at -10 °C. The reaction mixture was stirred at 0 °C for 35 min. Subsequently, the mixture was cooled to -70 °C and a solution of anhydrous THF (1 L) of 2-fluoro-3-iodopyridine (350 g, 1.57 mol) was added. The mixture was continued to be stirred at -70 °C for 2 hours. Ethyl formate (HCOOEt) (128 g, 1.73 mol) was slowly added dropwise while maintaining -70 °C. After the dropwise addition, the reaction mixture was gradually warmed up to room temperature and the reaction was quenched with ice water (4 L). The reaction mixture was diluted with ethyl acetate (EtOAc) (4 L) and the organic layer was washed with brine (500 mL). The organic layer was dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with the eluent being petroleum ether: ethyl acetate (10:1, v/v) to afford the target product 2-fluoro-4-iodopyridine-3-carbaldehyde (180 g, 46% yield) as a yellow solid.1H NMR (400 MHz, CDCl3) δ ppm: 10.08 (s, 1H), 7.91 (d, 1H), 7.81 (d, 1H). 1H).

References

[1] Journal of Organic Chemistry, 1993, vol. 58, # 27, p. 7832 - 7838
[2] Patent: WO2016/97918, 2016, A1. Location in patent: Page/Page column 58

4-IODO-2-FLUORO-3-FORMYLPYRIDINE Preparation Products And Raw materials

Raw materials

2-Fluoro-3-iodopyridine Ethyl formate n-Butyllithium Tetrahydrofuran Hexane

Diisopropylamine

1of2

Preparation Products

4-IODO-2-FLUORO-3-FORMYLPYRIDINE Suppliers

Global( 166)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Shanghai Arbor Chemical Co., Ltd.	021-60451682	act@arborchemical.com	CHINA	904	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shanghai Arbor Chemical Co., Ltd.	58
Jinan Carbotang Biotech Co.,Ltd.	58
HaBo Hong Kong Co., Limited.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 4-IODO-2-FLUORO-3-FORMYLPYRIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-16	4-IODO-2-FLUORO-3-FORMYLPYRIDINE 153034-82-3		1G	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.
2025-11-18	4-IODO-2-FLUORO-3-FORMYLPYRIDINE 153034-82-3	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2025-04-04	4-IODO-2-FLUORO-3-FORMYLPYRIDINE 153034-82-3		1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

4-IODO-2-FLUORO-3-FORMYLPYRIDINE
153034-82-3
$0.00
98%
Shenzhen Nexcon Pharmatechs Ltd.

4-IODO-2-FLUORO-3-FORMYLPYRIDINE
153034-82-3
$1.10
99.00%
Dideu Industries Group Limited

4-IODO-2-FLUORO-3-FORMYLPYRIDINE
153034-82-3
98%
Henan Aochuang Chemical Co.,Ltd.

4-IODO-2-FLUORO-3-FORMYLPYRIDINE Spectrum

4-IODO-2-FLUORO-3-FORMYLPYRIDINE(153034-82-3)¹HNMR 4-IODO-2-FLUORO-3-FORMYLPYRIDINE(153034-82-3)¹⁹FNMR

153034-82-3(4-IODO-2-FLUORO-3-FORMYLPYRIDINE)Related Search:

2-Fluoro-4-iodopyridine 2-Fluoro-3-iodopyridine 2-Fluoro-3-methylpyridine 4-IODO-2-FLUORO-3-FORMYLPYRIDINE 2-FLUORO-4-IODO-3-PICOLINE

4-Iodopyridine 4-Iodo-3-methylpyridine 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 2-FLUORO-4-IODONICOTINIC ACID 2-FLUORO-3-FORMYLPYRIDINE

1of2

2-FLUORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE 4-IODO-2-FLUORO-3-FORMYLPYRIDINE 2-fluoro-4-iodonicotaldehyde 2-FLUORO-3-FORMYL-4-IODOPYRIDINE 2-Fluoro-4-iodo-3-pyridinecarboxaldehyde 2 - F -3 - aldehyde -4 - iodine pyridine 2-Fluoro-4-iodopyridine-3-carbaldehyde 2-Fluoro-4-iodopyridine-3-carboxaldehyde, 2-Fluoro-3-formyl-4-iodopyridine 2-fluoro-4-iodo-3-pyridinecarboxyaldehyde 3-Pyridinecarboxaldehyde, 2-fluoro-4-iodo- [(fluoro-2-iodo-4)pyrid-3-yl]-carboxaldehyde 4-IODO-2-FLUORO-3-FORMYLPYRIDINE ISO 9001：2015 REACH 2-fluoro-4-iodo3-aldehyde pyridine 2-FLUORO-4-IODONICOTINALDEHYDE 153034-82-3 C6H3FINO Fluorine series Pyridines Pyridine