2-Amino-3-chlorobenzoic acid
- CAS No.
- 6388-47-2
- Chemical Name:
- 2-Amino-3-chlorobenzoic acid
- Synonyms
- 3-CHLOROANTHRANILIC ACID;NSC 20671;2-Amino-3-chL;2-Amino-3-chloro;BUTTPARK 24\07-98;TIMTEC-BB SBB003844;2-Amino-3-chlorbenzoesure;3-ChloroanthranilicAcid>3-CHLORO-2-AMINOBENZOIC ACID;2-AMINO-3-CHLOROBENZOIC ACID
- CBNumber:
- CB2430094
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MDL Number:
- MFCD00134229
- MOL File:
- 6388-47-2.mol
- MSDS File:
- SDS
| Melting point | 189-191 °C (lit.) |
|---|---|
| Boiling point | 0°C |
| Density | 1.476±0.06 g/cm3(Predicted) |
| Flash point | 0°C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanaol |
| pka | 4.57±0.10(Predicted) |
| form | Solid |
| color | Yellow to brown |
| Water Solubility | Soluble in water. |
| Sensitive | Air & Light Sensitive |
| InChI | InChI=1S/C7H6ClNO2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,9H2,(H,10,11) |
| InChIKey | LWUAMROXVQLJKA-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(Cl)=C1N |
| CAS DataBase Reference | 6388-47-2(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| WGK Germany | 1 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
2-Amino-3-chlorobenzoic acid price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 362271 | 2-Amino-3-chlorobenzoic acid 95% | 6388-47-2 | 1g | $71.8 | 2023-06-20 | Buy |
| TCI Chemical | A0786 | 3-Chloroanthranilic Acid >98.0%(T) | 6388-47-2 | 5g | $71 | 2025-07-31 | Buy |
| TCI Chemical | A0786 | 3-Chloroanthranilic Acid >98.0%(T) | 6388-47-2 | 25g | $221 | 2025-07-31 | Buy |
| TRC | A603395 | 2-Amino-3-chlorobenzoic acid | 6388-47-2 | 25g | $135 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0018274 | 2-AMINO-3-CHLOROBENZOIC ACID 95.00% | 6388-47-2 | 1G | $154.35 | 2021-12-16 | Buy |
2-Amino-3-chlorobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
white to yellow, tan or grey crystalline powder
Uses
2-Amino-3-chlorobenzoic acid is used as pharmaceutical intermediates.
Uses
2-Amino-3-chlorobenzoic Acid is a plant growth regulator.
Synthesis Reference(s)
The Journal of Organic Chemistry, 17, p. 141, 1952 DOI: 10.1021/jo01135a014
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
The synthesis of 2-Amino-3-chlorobenzoic acid is as follows:
70 ml of methanol was added to an autoclave, and cooled to -70° C., and 16 g (942 mmol) of a generated ammonia gas was added. 30 g (157 mmol) of 2,3-dichlorobenzoic acid and 0.78 g (7.85 mmol) of copper(I) chloride were added. The autoclave was sealed, and heated in an oil bath at 130° C. and 30 atmospheres for 20 hours. After the completion of the reaction, the autoclave was cooled to room temperature, and the reaction mixture was transferred into a reaction flask. 100 ml of water was added to the reaction solution, and the reaction solution was heated in an oil bath to 100° C. to remove the ammonia and the methanol. Then, the reaction solution was cooled to room temperature, and hydrochloric acid was added to adjust the pH value to 3. The precipitated crystals were filtered and dried to obtain 21.8 g of 2-amino-3-chlorobenzoic acid as white crystals with a yield of 81%.
References
[1] Chemical and Pharmaceutical Bulletin, 1989, vol. 37, # 8, p. 2207 - 2208
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 1411 - 1416
[3] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 27
[4] Patent: WO2010/79431, 2010, A2. Location in patent: Page/Page column 71-73
[5] Patent: WO2003/106435, 2003, A1. Location in patent: Page 292; 293
2-Amino-3-chlorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +1-5184799099 | lbaochemicals@gmail.com | China | 278 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2161 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2953 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 2-Amino-3-chlorobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-08 | 2-amino-3-chlorobenzoic acid
6388-47-2
|
US $0.00 / kg | 1kg | 98% | Customise | Hefei Lbao Physical & Chemical Science Co.,Ltd | |
 |
2019-07-06 | 2-Amino-3-chlorobenzoic acid
6388-47-2
|
US $8.00 / kg | 1kg | 99% | 100KG | Career Henan Chemical Co |
-
- 2-amino-3-chlorobenzoic acid
6388-47-2
- US $0.00 / kg
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 2-Amino-3-chlorobenzoic acid
6388-47-2
- US $8.00 / kg
- 99%
- Career Henan Chemical Co
