ChemicalBook >> CAS DataBase List >>6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

CAS No.
57196-62-0
Chemical Name:
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Synonyms
6-Methoxy-1,2,3,4-tetrahydrois;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HCL;ISOQUINOLINE 1,2,3,4-TETRAHYDRO-6-METHOXY HCL SALT;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE;1,2,3,4-tetrahydro-6-methoxyisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetraihydroisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride,95%;Isoquinoline, 1,2,3,4-tetrahydro-6-Methoxy-, hydrochloride;Isoquinoline,1,2,3,4-tetrahydro-6-methoxy-,hydrochloride(1:1);Better offer for 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
CBNumber:
CB2501596
Molecular Formula:
C10H14ClNO
Molecular Weight:
199.68
MDL Number:
MFCD01717328
MOL File:
57196-62-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:37:42

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Properties

Melting point 230-232.5°C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
Appearance White to off-white Solid
InChI 1S/C10H13NO.ClH/c1-12-10-3-2-9-7-11-5-4-8(9)6-10;/h2-3,6,11H,4-5,7H2,1H3;1H
InChIKey QIUIKPQXMJJOQT-UHFFFAOYSA-N
SMILES Cl.COc1ccc2CNCCc2c1
CAS DataBase Reference 57196-62-0
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280g-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22-51
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  2933491090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
NFPA 704
1
2 0

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 64311 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% 57196-62-0 1G $29 2026-04-30 Buy
AstaTech 64311 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% 57196-62-0 5G $99 2026-04-30 Buy
AstaTech 64311 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% 57196-62-0 25G $292 2026-04-30 Buy
Chem-Impex 17763 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride ≥96% 57196-62-0 100MG $65.4 2026-05-19 Buy
Chem-Impex 17763 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride ≥96% 57196-62-0 250MG $112.67 2026-05-19 Buy
Product number Packaging Price Buy
64311 1G $29 Buy
64311 5G $99 Buy
64311 25G $292 Buy
17763 100MG $65.4 Buy
17763 250MG $112.67 Buy

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Properties, Uses, Production

Synthesis

Formaldehyde

50-00-0

4-Methoxyphenethylamine

55-81-2

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

57196-62-0

To a stirred suspension of 4-methoxyphenethylamine (50.4 g, 0.33 mol, 1.0 eq.) in water (40 mL) was slowly added 37% aqueous formaldehyde (27.5 mL, 1.1 eq.) with continuous stirring for 20 minutes. Subsequently, concentrated hydrochloric acid (80 mL) was added dropwise to the reaction mixture and the mixture was heated to reflux and maintained for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was purified by recrystallization from acetone to afford 6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride as a white solid (60.1 g, 90% yield). The product did not require further purification and could be used directly in the subsequent reaction. Mass spectrometry analysis showed that the MH+ peak was located at 164.

References

[1] Patent: WO2003/99786, 2003, A2. Location in patent: Page 35

Global Suppliers ( 139)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Boc Chemical Co.,Ltd 021-34975603-808 18721111801 sales@bocpharma.com China 991 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
China Langchem Inc. 0086-21-58956006 China 7798 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60

View Latest Price from 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride pictures 2025-04-04 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride pictures 2020-01-10 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
$1.00 1g 99% 10000kgs Career Henan Chemical Co

6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Spectrum

6-Methoxy-1,2,3,4-tetrahydrois 1,2,3,4-tetrahydro-6-methoxyisoquinoline hydrochloride Isoquinoline, 1,2,3,4-tetrahydro-6-Methoxy-, hydrochloride 6-Methoxy-1,2,3,4-tetraihydroisoquinoline hydrochloride ISOQUINOLINE 1,2,3,4-TETRAHYDRO-6-METHOXY HCL SALT 6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HCL 6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE Isoquinoline,1,2,3,4-tetrahydro-6-methoxy-,hydrochloride(1:1) 6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride,95% Better offer for 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride 57196-62-0 API intermediates