6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
- CAS No.
- 57196-62-0
- Chemical Name:
- 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
- Synonyms
- 6-Methoxy-1,2,3,4-tetrahydrois;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HCL;ISOQUINOLINE 1,2,3,4-TETRAHYDRO-6-METHOXY HCL SALT;6-METHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE;1,2,3,4-tetrahydro-6-methoxyisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetraihydroisoquinoline hydrochloride;6-Methoxy-1,2,3,4-tetrahydroisoquinolinehydrochloride,95%;Isoquinoline, 1,2,3,4-tetrahydro-6-Methoxy-, hydrochloride;Isoquinoline,1,2,3,4-tetrahydro-6-methoxy-,hydrochloride(1:1);Better offer for 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
- CBNumber:
- CB2501596
- Molecular Formula:
- C10H14ClNO
- Molecular Weight:
- 199.68
- MDL Number:
- MFCD01717328
- MOL File:
- 57196-62-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 230-232.5°C |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| Appearance | White to off-white Solid |
| InChI | 1S/C10H13NO.ClH/c1-12-10-3-2-9-7-11-5-4-8(9)6-10;/h2-3,6,11H,4-5,7H2,1H3;1H |
| InChIKey | QIUIKPQXMJJOQT-UHFFFAOYSA-N |
| SMILES | Cl.COc1ccc2CNCCc2c1 |
| CAS DataBase Reference | 57196-62-0 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280g-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-51 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933491090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 |
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| NFPA 704 |
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6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 64311 | 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% | 57196-62-0 | 1G | $29 | 2026-04-30 | Buy |
| AstaTech | 64311 | 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% | 57196-62-0 | 5G | $99 | 2026-04-30 | Buy |
| AstaTech | 64311 | 6-METHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HCL 97% | 57196-62-0 | 25G | $292 | 2026-04-30 | Buy |
| Chem-Impex | 17763 | 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride ≥96% | 57196-62-0 | 100MG | $65.4 | 2026-05-19 | Buy |
| Chem-Impex | 17763 | 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride ≥96% | 57196-62-0 | 250MG | $112.67 | 2026-05-19 | Buy |
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Properties, Uses, Production
Synthesis
50-00-0
55-81-2
57196-62-0
To a stirred suspension of 4-methoxyphenethylamine (50.4 g, 0.33 mol, 1.0 eq.) in water (40 mL) was slowly added 37% aqueous formaldehyde (27.5 mL, 1.1 eq.) with continuous stirring for 20 minutes. Subsequently, concentrated hydrochloric acid (80 mL) was added dropwise to the reaction mixture and the mixture was heated to reflux and maintained for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated to dryness in a rotary evaporator. The resulting residue was purified by recrystallization from acetone to afford 6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride as a white solid (60.1 g, 90% yield). The product did not require further purification and could be used directly in the subsequent reaction. Mass spectrometry analysis showed that the MH+ peak was located at 164.
References
[1] Patent: WO2003/99786, 2003, A2. Location in patent: Page 35
6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Boc Chemical Co.,Ltd | 021-34975603-808 18721111801 | sales@bocpharma.com | China | 991 | 64 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 999 | 60 |
View Latest Price from 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
![]() |
2020-01-10 | 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
|
$1.00 | 1g | 99% | 10000kgs | Career Henan Chemical Co |
-

- 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
57196-62-0
- $1.00
- 99%
- Career Henan Chemical Co





