Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-Chloro-5-methylthiazole

2-Chloro-5-methylthiazole

2-Chloro-5-methylthiazole Structure
2-Chloro-5-methylthiazole structure
CAS No.
33342-65-3
Chemical Name:
2-Chloro-5-methylthiazole
Synonyms
chloro-5-methylthiazole;2-CHLORO-5-METHYLTHIAZOLE;Thiazole,2-chloro-5-Methyl-;2-chloro-5-methyl-1,3-thiazole;2-Chloro-5-methylthiazole, CAS 33342-65-3;2-CHLORO-5-METHYLTHIAZOLE(PHENYLOXINDOLE)
CBNumber:
CB2721969
Molecular Formula:
C4H4ClNS
Molecular Weight:
133.6
MDL Number:
MFCD03265390
MOL File:
33342-65-3.mol
MSDS File:
SDS
Last updated:2026-08-28 09:47:24
Request For Quotation

2-Chloro-5-methylthiazole Properties

Boiling point 51-58 °C(Press: 11.5 Torr)
Density 1.331±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.32±0.10(Predicted)
Appearance Colorless to light yellow Liquid
CAS DataBase Reference 33342-65-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2934100090

2-Chloro-5-methylthiazole price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth IBA34265 2-Chloro-5-methylthiazole 33342-65-3 10g $354 2026-06-04 Buy
Apolloscientific OR928350 2-Chloro-5-methylthiazole >98% 33342-65-3 250mg $21 2026-06-04 Buy
Apolloscientific OR928350 2-Chloro-5-methylthiazole >98% 33342-65-3 1g $26 2026-06-04 Buy
Apolloscientific OR928350 2-Chloro-5-methylthiazole >98% 33342-65-3 5g $101 2026-06-04 Buy
Apolloscientific OR928350 2-Chloro-5-methylthiazole >98% 33342-65-3 25g $496 2026-06-04 Buy
Product number Packaging Price Buy
IBA34265 10g $354 Buy
OR928350 250mg $21 Buy
OR928350 1g $26 Buy
OR928350 5g $101 Buy
OR928350 25g $496 Buy

2-Chloro-5-methylthiazole Chemical Properties, Uses, Production

Uses

2-Chloro-5-methylthiazole is used as a pesticide intermediate.

Synthesis

2-Amino-5-methylthiazole

7305-71-7

2-Chloro-5-methylthiazole

33342-65-3

(1) Preparation of 2-chloro-5-methylthiazole: 72 g (0.6 mol) of tert-butyronitrile was dissolved in 1.5 L of anhydrous acetonitrile to prepare a solution. Under nitrogen protection, 65 g (0.48 mol) of anhydrous copper (II) chloride was added to the reaction vessel. Under vigorous stirring and nitrogen atmosphere, the tert-butyl nitrile solution was slowly added to the reaction vessel. Subsequently, 45.6 g (0.40 mol) of 2-amino-5-methylthiazole was added in batches at 25 °C for about 40 min addition. The reaction mixture was continued to be stirred at 25°C for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of 20% hydrochloric acid solution. The solvent was removed by distillation under reduced pressure. To the residue, 300 mL of chloroform was added and the organic phase was washed with saturated saline (100 mL x 3). The organic layer was dried with anhydrous magnesium sulfate and the solvent was removed by distillation under reduced pressure to give 49.7 g of 2-chloro-5-methylthiazole in 93% yield.

References

[1] Patent: CN108164522, 2018, A. Location in patent: Paragraph 0027; 0028; 0032; 0036
[2] Patent: CN108276357, 2018, A. Location in patent: Paragraph 0024; 0025; 0031
[3] Patent: CN105622542, 2016, A. Location in patent: Paragraph 0014; 0015
[4] Chemistry - A European Journal, 2018, vol. 24, # 55, p. 14622 - 14626
[5] Patent: US5811555, 1998, A

2-Chloro-5-methylthiazole synthesis

7305-71-7
33342-65-3
Synthesis of 2-Chloro-5-methylthiazole from 2-Amino-5-methylthiazole

2-Chloro-5-methylthiazole Preparation Products And Raw materials

Raw materials

5-Methylthiazole-2(3H)-thione 5-Methylthiazol-2-amine hydrochloride 5-Methylene-1,3-thiazolidine-2-thione 5-Methylthiazol-2-ol 2-Chlorothiazole
2-Amino-5-methylthiazole Iodomethane Copper(II) chloride Acetonitrile

1of2

Preparation Products

5-Methylthiazole

2-Chloro-5-methylthiazole Suppliers

Global Suppliers ( 147)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4263 65
China Langchem Inc. 0086-21-58956006 China 7798 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 027-8866 0053/88660577/88660578 China 1070 55
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Candia Thamtech Company Limited 0371-86615086 18203638366 0371-86159066 13526786601 China 2011 60
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Supplier Advantage
Pure Chemistry Scientific Inc. 62
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Ennopharm Co., Ltd. 65
China Langchem Inc. 57
Wuhan Haizheng Industry & Trade Development Co. Ltd 55
Shanghai T&W Pharmaceutical Co., Ltd. 58
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Candia Thamtech Company Limited 60
9ding chemical ( Shanghai) Limited 56

View Latest Price from 2-Chloro-5-methylthiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-5-methylthiazole pictures 2019-08-30 2-Chloro-5-methylthiazole
33342-65-3
 $1.00 1KG 98% 200kg Career Henan Chemical Co

2-Chloro-5-methylthiazole Spectrum

2-Chloro-5-methylthiazole(33342-65-3)1HNMR

33342-65-3 (2-Chloro-5-methylthiazole) Related Search:

tert-Butyldimethylsilyl chloride Dimethylthexylsilyl chloride 2-Chlorothiazole 5-Methylthiazole 2-Chloro-5-chloromethylthiazole
Chloromethane 2-Methyl-4-isothiazolin-3-one Vinylbenzyl chloride 4-(Chloromethyl)benzoic acid Difluorochloromethane
2-CHLORO-4-METHYLTHIAZOLE-5-SULFONAMIDE Chloromethyl methyl ether 2-Chloro-4-methyl-thiazole Ethyl 2-chloro-4-methyl-1,3-thiazole-5-carboxylate 2-Chloro-5-methylthiazole
5-chloro-4-methylthiazole 4-(4-Bromophenyl)-2-chloro-5-methylthiazole 2-Amino-5-chloro-4-methylthiazole

1of4

2-CHLORO-5-METHYLTHIAZOLE 2-CHLORO-5-METHYLTHIAZOLE(PHENYLOXINDOLE) 2-chloro-5-methyl-1,3-thiazole Thiazole,2-chloro-5-Methyl- chloro-5-methylthiazole 2-Chloro-5-methylthiazole, CAS 33342-65-3 33342-65-3 3342-65-3