ChemicalBook >> CAS DataBase List >>Epinastine hydrobromide
Epinastine hydrobromide
- CAS No.
- 127786-29-2
- Chemical Name:
- Epinastine hydrobromide
- Synonyms
- EPINASTIN HBR;Epinastine HBr;Epinastine-13C-d3 HBr;Epinastin hydrobromide;epinastine hydrobromide;9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrobromide;9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine monohydrobromide;(+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide;6-Aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine (E)-2-butenedioate Epinastine hydrobromide
- CBNumber:
- CB2854847
- Molecular Formula:
- C16H16BrN3
- Molecular Weight:
- 330.22234
- MDL Number:
- MOL File:
- 127786-29-2.mol
- MSDS File:
- SDS
Last updated:2026-05-28 00:50:33
| Melting point | 284-286° |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| InChI | InChI=1S/C16H15N3.BrH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H |
| InChIKey | ADPMHRDERZTFIN-UHFFFAOYSA-N |
| SMILES | N12C(N)=NCC1C1C=CC=CC=1CC1C=CC=CC2=1.Br |
| FDA UNII | 4O6LIW7G3N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| REACH Registrations | Active |
Epinastine hydrobromide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CFA78629 | 9,13b-Dihydro-1H-dibenzo[C,F]imidazo[1,5-a]azepin-3-amine hydrobromide | 127786-29-2 | 100mg | $250 | 2026-06-04 | Buy |
| Biosynth | CFA78629 | 9,13b-Dihydro-1H-dibenzo[C,F]imidazo[1,5-a]azepin-3-amine hydrobromide | 127786-29-2 | 50mg | $250 | 2026-06-04 | Buy |
| Biosynth | CFA78629 | 9,13b-Dihydro-1H-dibenzo[C,F]imidazo[1,5-a]azepin-3-amine hydrobromide | 127786-29-2 | 250mg | $360 | 2026-06-04 | Buy |
| Biosynth | CFA78629 | 9,13b-Dihydro-1H-dibenzo[C,F]imidazo[1,5-a]azepin-3-amine hydrobromide | 127786-29-2 | 500mg | $580 | 2026-06-04 | Buy |
| Biosynth | CFA78629 | 9,13b-Dihydro-1H-dibenzo[C,F]imidazo[1,5-a]azepin-3-amine hydrobromide | 127786-29-2 | 1000mg | $940 | 2026-06-04 | Buy |
Epinastine hydrobromide Chemical Properties, Uses, Production
Application
Clinical studies have shown that, at the same dosage, epinastine hydrochloride is significantly more effective than other second-generation histamine H1 receptor antagonists such as terfenadine, astamiva, and ketotifen, and also has a lower incidence of central sedation and cardiotoxicity. Therefore, the market demand for epinastine hydrochloride is substantial, making its synthesis necessary. Literature searches reveal that publicly available patents and literature use 6-aminomethyl-6,11-dihydro-5H-dibenzo[b,e]azapyridine (Ⅳ) as a key intermediate in epinastine synthesis, which is cyclized with cyanogen bromide to yield epinastine. Epinastine hydrobromide is also a synthetic intermediate for epinastine.
Epinastine hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 55)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Xiao Bei Medical Technology Co., LTD | +86-571-8526 3177 13962438025 | beixi.dong@heryipharma.com | China | 196 | 58 |
| Nanjing Hequan New Materials Technology Co., Ltd. | 18355039361 | 18355039361@163.com | China | 30 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451683 15021268886 | sales@arborchemical.com | China | 765 | 55 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10244 | 55 |
| Shanghai QianJin Chemical Technology Co., Ltd | 021-20900665 17321230821 | 2986274987@qq.com | China | 754 | 55 |
| Nanjing Duolong Bio-tech Co.,Ltd. | 18905173768 | 52513593@qq.com | China | 2337 | 50 |
| Watson Biotechnology Co.,Ltd | 027-59207879 1972026995 18140587686 | sales@3600chem.com | China | 4180 | 55 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4511 | 58 | |
| Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. | 027-51831887 15337167856 | hubeixinyuanshun@163.com | China | 10272 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29090 | 58 |
View Latest Price from Epinastine hydrobromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | Epinastine hydrobromide
127786-29-2
|
$2.00 | 1KG | 98% | 100g , 1kg, 5kg , 50kg | Career Henan Chemical Co |
-
- Epinastine hydrobromide
127786-29-2
- $2.00
- 98%
- Career Henan Chemical Co
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1of4
Epinastine-13C-d3 HBr
(+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide
EPINASTIN HBR
Epinastine HBr
9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrobromide
epinastine hydrobromide
Epinastin hydrobromide
6-Aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine (E)-2-butenedioate Epinastine hydrobromide
9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine monohydrobromide
127786-29-2
C16H15N3HBr
