1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
- CAS No.
- 33301-41-6
- Chemical Name:
- 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
- Synonyms
- 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE;1-Diphenylmethyl-3-azetidinyl Methanethiosulfonate;BUTTPARK 37\04-14;1-(Diphenylmethyl)-3-(mesyloxy)azetidine;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE;1-Benzhydryl-3-azetidinyl methanesulfonate;1-Benzhydryl-3-methanesulphonyloxyazetidine;1-BENZHYDRYL-3-METHANESULFONYLOXY AZETIDINE;1-BENZHYDRYL-3-METHANESULFONATOAZETIDINE 98%;1-Benzhydryl-3-azetidinylMethanesulfonate>
- CBNumber:
- CB3111828
- Molecular Formula:
- C17H19NO3S
- Molecular Weight:
- 317.4
- MDL Number:
- MFCD00159216
- MOL File:
- 33301-41-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(DIPHENYLMETHYL)-3-AZETIDINYL METHANESULFONATE AldrichCPR | S906700 | 1 unit | $32.7 |
| 1-(DIPHENYLMETHYL)-3-AZETIDINYL METHANESULFONATE Aldrich | S906700 | 50mg | $29.8 |
| 1-Benzhydryl-3-azetidinyl Methanesulfonate >95.0%(HPLC)(T) | D4131 | 1g | $205 |
| 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE 97% | 52659 | 1G | $10 |
| 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE 97% | 52659 | 5G | $25 |
| More product size | |||
| Melting point | 111-112°C |
|---|---|
| Boiling point | 459.9±34.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Dichloromethane, Ether, Ethyl Acetate, Methanol |
| form | Solid |
| pka | 5.67±0.10(Predicted) |
| color | White |
| InChI | InChI=1S/C17H19NO3S/c1-22(19,20)21-16-12-18(13-16)17(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3 |
| InChIKey | MSVZMUILYMLJCF-UHFFFAOYSA-N |
| SMILES | N1(C(C2=CC=CC=C2)C2=CC=CC=C2)CC(OS(C)(=O)=O)C1 |
| CAS DataBase Reference | 33301-41-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Safety Statements | 24/25 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S906700 | 1-(DIPHENYLMETHYL)-3-AZETIDINYL METHANESULFONATE AldrichCPR | 33301-41-6 | 1 unit | $32.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | S906700 | 1-(DIPHENYLMETHYL)-3-AZETIDINYL METHANESULFONATE Aldrich | 33301-41-6 | 50mg | $29.8 | 2024-03-01 | Buy |
| TCI Chemical | D4131 | 1-Benzhydryl-3-azetidinyl Methanesulfonate >95.0%(HPLC)(T) | 33301-41-6 | 1g | $205 | 2023-06-20 | Buy |
| AstaTech | 52659 | 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE 97% | 33301-41-6 | 1G | $10 | 2026-04-30 | Buy |
| AstaTech | 52659 | 1-BENZHYDRYLAZETIDIN-3-YL METHANESULFONATE 97% | 33301-41-6 | 5G | $25 | 2026-04-30 | Buy |
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
A proline analog and proline formation inhibitor
Synthesis
Preparation procedure of 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate: To a reaction flask was charged 632 g (2.64 mol) of 1-benzhydrylazetidin- 3-ol, acetonitrile (1.9 L), and triethylamine (601 g, 1.5 equiv). The mixture was cooled in an ice-acetone bath (-5 °C). Methanesulfonyl chloride (436 g, 1.20 equiv) was added via a drop funnel while keeping the reaction temperature at less than5 °C. HPLC showed reaction completion after 15 min. Water (6.3 L) was added, and the reaction mixture was stirred for 2 h at room temperature and filtered. The filter cake was rinsed with water (2 x 1 L), pulled dry under vacuum, and directly subjected to the amination reaction in the next step. Yield 100%.
References
[1] Patent: US2005/54697, 2005, A1. Location in patent: Page/Page column 78
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 4, p. 1084 - 1088
[3] Patent: WO2011/61214, 2011, A1. Location in patent: Page/Page column 85-86
[4] Patent: US2014/288045, 2014, A1. Location in patent: Paragraph 0605
[5] Patent: WO2016/44772, 2016, A1. Location in patent: Paragraph 319
1-(Diphenylmethyl)-3-azetidinyl methanesulfonate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2163 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9036 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9857 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9322 | 58 |
View Lastest Price from 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-26 | 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
|
$1.50-31.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-04-04 | 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2021-07-13 | 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
- $1.50-31.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1-(Diphenylmethyl)-3-azetidinyl methanesulfonate
33301-41-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
