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H-PRO-HYP-OH

H-PRO-HYP-OH structure

CAS No.: 18684-24-7

Chemical Name:: H-PRO-HYP-OH

Synonyms: Prolylhydroxyproline;Dipeptide-6;Pro-Hyp;P-(Hyp);Hyp-Gly;H-PRO-HYP-OH;PRO-HYDROXY-PRO;L-PRO-HYPRO-PRO;Pro-Hyp zwitterion;Pro-Hyp-OH≥ 99% (TLC)

CBNumber:: CB3207664

Molecular Formula:: C10H16N2O4

Molecular Weight:: 228.24

MDL Number:: MFCD00037349

MOL File:: 18684-24-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:17

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H-PRO-HYP-OH Properties

Boiling point	513.5±50.0 °C(Predicted)
Density	1.417±0.06 g/cm3(Predicted)
storage temp.	-15°C
solubility	Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	2.98±0.40(Predicted)
color	White to Off-White
Stability	Hygroscopic
Cosmetics Ingredients Functions	SKIN CONDITIONING - MISCELLANEOUS SKIN CONDITIONING

H-PRO-HYP-OH price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	287856	Pro-Hyp-OH Asreported	18684-24-7	25mg	$382	2026-06-03	Buy
Usbiological	287856	Pro-Hyp-OH Asreported	18684-24-7	50mg	$582	2026-06-03	Buy
Usbiological	287856	Pro-Hyp-OH Asreported	18684-24-7	100mg	$818	2026-06-03	Buy
Usbiological	241365	Pro-Hyp-OH 99+% (TLC) ≥99%(TLC)		100mg	$319	2026-06-03	Buy
Biosynth	FP49344	Pro-Hyp-OH	18684-24-7	0.05g	$199.54	2026-06-04	Buy

Product number	Packaging	Price	Buy
287856	25mg	$382	Buy
287856	50mg	$582	Buy
287856	100mg	$818	Buy
241365	100mg	$319	Buy
FP49344	0.05g	$199.54	Buy

H-PRO-HYP-OH Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging[1].

Definition

ChEBI: Pro-Hyp is a dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation. It has a role as a diagnostic agent, a human metabolite and a biomarker. It is functionally related to a L-proline and a trans-4-hydroxy-L-proline. It is a tautomer of a Pro-Hyp zwitterion.

References

[1] Tedesco L, et al. A designer mixture of six amino acids promotes the extracellular matrix gene expression in cultured human fibroblasts. Biosci Biotechnol Biochem. 2022 Aug 24;86(9):1255-1261. DOI:10.1093/bbb/zbac101

H-PRO-HYP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

H-PRO-HYP-OH Suppliers

Global( 114)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60
Syntechem Co.,Ltd		info@syntechem.com	China	12973	57
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	1010	55
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29985	65
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Balmxy Pharmaceutical Co., Ltd	021-24206007 13764915196	sales@balmxy.com	China	6959	55
NINGBO INNO PHARMCHEM CO.,LTD.	86-574-27787657	info@dearchem.com	China	4607	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60
Syntechem Co.,Ltd	57
Cellmano Biotech Limited	55
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
Bide Pharmatech Ltd.	60
Shanghai Balmxy Pharmaceutical Co., Ltd	55
NINGBO INNO PHARMCHEM CO.,LTD.	58

View Lastest Price from H-PRO-HYP-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-10	Dipeptide-6 18684-24-7	$100.00	1PC	99%	1000kg	Huaian Banting Trading Co., Ltd.
2024-10-18	Dipeptide-6 18684-24-7	$30.00	1Box	99.99%	10000000000	zhuzhou dingcheng meihei comestic co.,ltd
2024-06-04	H-PRO-HYP-OH 18684-24-7	$20.00	1box	99%	100000box	Shanghai Getian Industrial Co., LTD

Dipeptide-6
18684-24-7
$100.00
99%
Huaian Banting Trading Co., Ltd.

Dipeptide-6
18684-24-7
$30.00
99.99%
zhuzhou dingcheng meihei comestic co.,ltd

H-PRO-HYP-OH
18684-24-7
$20.00
99%
Shanghai Getian Industrial Co., LTD

H-PRO-HYP-OH Spectrum

H-PRO-HYP-OH(18684-24-7)¹HNMR H-PRO-HYP-OH(18684-24-7)¹³CNMR

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(S)-(+)-1-Methyl-3-pyrrolidinol (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine H-PRO-GLY-OH AKOS BB-9805 1-propionylpyrrolidine-2-carboxylic acid

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1of4

PRO-HYDROXY-PRO H-PRO-HYP-OH L-PRO-HYPRO-PRO (2S,4R)-4-hydroxy-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid (2S,4R)-4-hydroxy-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid L-Prolyl-L-hydroxyproline Pro-Hyp-OH≥ 99% (TLC) Pro-Hyp zwitterion 4-Hydroxy-1-L-prolyl-L-proline 4-hydroxy-1-[oxo(2-pyrrolidinyl)methyl]-2-pyrrolidinecarboxylic acid L-Proline, L-prolyl-4-hydroxy-, (4R)- H-PRO-HYP-OH USP/EP/BP (2S,4R)-1-(L-prolyl)-4-hydroxypyrrolidine-2-carboxylic acid P-(Hyp) Hyp-Gly H-Pro-Hyp-OH（TFA Salt） L-Prolyl-[(4R)-4-hydroxy-L-proline Dipeptide-6、Prolyl-hydroxyproline (2S,4R)-1-(L-prolyl)-4-hydroxypyrrolidine-2-carboxylic acid - [P89155] Dipeptide-6 Prolylhydroxyproline Pro-Hyp 18684-24-7 188684-24-7 C10H16N2O4