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GSK2190915 (sodiuM salt)

GSK2190915 (sodiuM salt) Structure
GSK2190915 (sodiuM salt) structure
CAS No.
1196070-26-4
Chemical Name:
GSK2190915 (sodiuM salt)
Synonyms
GSK-2190915A;AM-803 sodium);Fiboflapon sodium;GSK2190915 Sodium;GSK2190915 (sodiuM salt);GSK2190915 sodium (GSK-2190915A;FIBOFLAPON SODIUM;FIBOFLAPON SODIUM
CBNumber:
CB32735523
Molecular Formula:
C38H44N3NaO4S
Molecular Weight:
661.84
MDL Number:
MOL File:
1196070-26-4.mol
Last updated:2025-04-18 09:52:05
Product description Number Pack Size Price
Fiboflaponsodium 99.08% CS-3605 5mg $151
sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate B4905 5mg $189
Fiboflaponsodium 99.08% CS-3605 10mg $252
sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate B4905 10mg $315
sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate B4905 2mg $126
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GSK2190915 (sodiuM salt) Properties

form Powder
color White to off-white
FDA UNII 75YS00XOG3

SAFETY

Risk and Safety Statements

Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

GSK2190915 (sodiuM salt) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-3605 Fiboflaponsodium 99.08% 1196070-26-4 5mg $151 2021-12-16 Buy
ApexBio Technology B4905 sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate 1196070-26-4 5mg $189 2021-12-16 Buy
ChemScene CS-3605 Fiboflaponsodium 99.08% 1196070-26-4 10mg $252 2021-12-16 Buy
ApexBio Technology B4905 sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate 1196070-26-4 10mg $315 2021-12-16 Buy
ApexBio Technology B4905 sodium 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate 1196070-26-4 2mg $126 2021-12-16 Buy
Product number Packaging Price Buy
CS-3605 5mg $151 Buy
B4905 5mg $189 Buy
CS-3605 10mg $252 Buy
B4905 10mg $315 Buy
B4905 2mg $126 Buy

GSK2190915 (sodiuM salt) Chemical Properties,Uses,Production

Uses

Fiboflapon sodium (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood[1].

IC 50

LTB4: 76 nM (IC50)

References

[1] Stock NS, et al. 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor. J Med Chem. 2011 Dec 8;54(23):8013-29. DOI:10.1021/jm2008369
[2] Lorrain DS, et al. Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. Eur J Pharmacol. 2010 Aug 25;640(1-3):211-8. DOI:10.1016/j.ejphar.2010.05.003

GSK2190915 (sodiuM salt) synthesis

59016-93-2
1196070-26-4
Synthesis of GSK2190915 (sodiuM salt) from 4-(Hydroxymethyl)phenylboronic acid

GSK2190915 (sodiuM salt) Preparation Products And Raw materials

Raw materials

ethyl 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoate 5-[4-(Chloromethyl)phenyl]-2-ethoxypyridine 4-(Hydroxymethyl)phenylboronic acid 1300640-22-5 1300640-23-6
1300640-24-7 5-Bromo-2-ethoxypyridine

1of2

Preparation Products

GSK2190915 (sodiuM salt) Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39032 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7552 61
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2384 58
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3866 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Haoyuan Chemexpress Co., Ltd. 61
LETOPHARM LIMITED 58
BOC Sciences 65
Guangzhou QiYun Biotechnology Co., Ltd. 58
ShangHai Biochempartner Co.,Ltd 62

View Lastest Price from GSK2190915 (sodiuM salt) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fiboflapon sodium pictures 2024-10-24 Fiboflapon sodium
1196070-26-4
 US $89.00-825.00 / mg 10g TargetMol Chemicals Inc.
GSK2190915 (sodiuM salt) GSK2190915 Sodium GSK-2190915A AM-803 sodium) Fiboflapon sodium GSK2190915 sodium (GSK-2190915A FIBOFLAPON SODIUM;FIBOFLAPON SODIUM 1196070-26-4 C38H42N3NaO4S