2-Bromo-5-fluorobenzonitrile
- CAS No.
- 57381-39-2
- Chemical Name:
- 2-Bromo-5-fluorobenzonitrile
- Synonyms
- Bromofluorobenzonitrile2;Bromo-5-fluorobenzonitrile;2-BROMO-5-FLUOROBENZONITRILE;2-Bromo-5-fluorobenzonitrile99%;Benzonitrile, 2-bromo-5-fluoro-;2-Bromo-5-fluorobenzonitrile >2-Bromo-5-fluorobenzonitrile 99%;2-Bromo-5-fluorobenzonitrile, 98+%;2 - broMine - 5 - fluorine benzene nitriles
- CBNumber:
- CB3296947
- Molecular Formula:
- C7H3BrFN
- Molecular Weight:
- 200.01
- MDL Number:
- MFCD00142875
- MOL File:
- 57381-39-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Bromo-5-fluorobenzonitrile 95% | 532754 | 25g | $261 |
| 2-Bromo-5-fluorobenzonitrile >97.0%(GC) | B3010 | 5g | $66 |
| 2-Bromo-5-fluorobenzonitrile >97.0%(GC) | B3010 | 25g | $187 |
| 2-Bromo-5-fluorobenzonitrile, min. 99% min.99% | 09-0040 | 25g | $120 |
| 2-Bromo-5-fluorobenzonitrile, min. 99% min.99% | 09-0040 | 100g | $360 |
| More product size | |||
| Melting point | 92-95 °C(lit.) |
|---|---|
| Boiling point | 251.2±25.0 °C(Predicted) |
| Density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in methanol. |
| form | powder to crystal |
| color | White to Yellow to Orange |
| BRN | 8678330 |
| InChI | InChI=1S/C7H3BrFN/c8-7-2-1-6(9)3-5(7)4-10/h1-3H |
| InChIKey | MDHNVHCZDCSTMS-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC(F)=CC=C1Br |
| CAS DataBase Reference | 57381-39-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,T,Xi | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
|||||||||
| NFPA 704 |
|
2-Bromo-5-fluorobenzonitrile price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 532754 | 2-Bromo-5-fluorobenzonitrile 95% | 57381-39-2 | 25g | $261 | 2023-01-07 | Buy |
| TCI Chemical | B3010 | 2-Bromo-5-fluorobenzonitrile >97.0%(GC) | 57381-39-2 | 5g | $66 | 2026-04-30 | Buy |
| TCI Chemical | B3010 | 2-Bromo-5-fluorobenzonitrile >97.0%(GC) | 57381-39-2 | 25g | $187 | 2026-04-30 | Buy |
| Strem Chemicals | 09-0040 | 2-Bromo-5-fluorobenzonitrile, min. 99% min.99% | 57381-39-2 | 25g | $120 | 2026-04-30 | Buy |
| Strem Chemicals | 09-0040 | 2-Bromo-5-fluorobenzonitrile, min. 99% min.99% | 57381-39-2 | 100g | $360 | 2026-04-30 | Buy |
2-Bromo-5-fluorobenzonitrile Chemical Properties,Uses,Production
Chemical Properties
Colorless solid
Uses
2-Bromo-5-fluorobenzonitrile is used in the synthesis of pyrimidine functional compounds acting as GABAAα2/α3 binding site agonists used in the treatment of anxiety disorders.
Uses
2-Bromo-5-fluorobenzonitrile may be used in the preparation of 5-chloro-4,2-difluorobiphenyl-2-carbonitrile.
General Description
2-Bromo-5-fluorobenzonitrile can be prepared from 3-fluorobenzonitrile vial bromination using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH).. It undergoes palladium-catalyzed Suzuki coupling with boronic acid derivative to form corresponding biaryl.
2-Bromo-5-fluorobenzonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 2-Bromo-5-fluorobenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-03-20 | 2-Bromo-5-fluorobenzonitrile
57381-39-2
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
![]() |
2020-01-09 | 2-Bromo-5-fluorobenzonitrile
57381-39-2
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-

- 2-Bromo-5-fluorobenzonitrile
57381-39-2
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Bromo-5-fluorobenzonitrile
57381-39-2
- $9.80
- ≥99%
- Career Henan Chemical Co





