Mal-PEG4-Glu(OH)-NH-m-PEG24
- CAS No.
- 2204309-09-9
- Chemical Name:
- Mal-PEG4-Glu(OH)-NH-m-PEG24
- Synonyms
- Mal-PEG4-Glu(OH)-NH-m-PEG24;MAL-dPEG??-Glu(OH)-NH-m-dPEG???;9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78-Tetracosaoxa-6-azanonaheptacontanoic acid, 4-[[19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1,17-dioxo-4,7,10,13-tetraoxa-16-azanonadec-1-yl]amino]-5-oxo-, (4S)-
- CBNumber:
- CB33162986
- Molecular Formula:
- C72H134N4O35
- Molecular Weight:
- 1615.84
- MDL Number:
- MFCD31657173
- MOL File:
- 2204309-09-9.mol
Mal-PEG4-Glu(OH)-NH-m-PEG24 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | bp-22753 | Mal-PEG4-Glu(OH)-NH-m-PEG24 90% | 2204309-09-9 | 50MG | $590 | 2026-05-24 | Buy |
| BroadPharm | bp-22753 | Mal-PEG4-Glu(OH)-NH-m-PEG24 90% | 2204309-09-9 | 100MG | $790 | 2026-05-24 | Buy |
| BroadPharm | bp-22753 | Mal-PEG4-Glu(OH)-NH-m-PEG24 90% | 2204309-09-9 | 250MG | $1200 | 2026-05-24 | Buy |
| dPEG | 11580 | MAL-dPEG®₄-Glu(OH)-NH-m-dPEG®₂₄ | 2204309-09-9 | 250mg | $875 | 2021-12-16 | Buy |
Mal-PEG4-Glu(OH)-NH-m-PEG24 Chemical Properties, Uses, Production
Uses
Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Mal-PEG4-Glu(OH)-NH-m-PEG24 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mal-PEG4-Glu(OH)-NH-m-PEG24 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6347 | 58 | |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80514535 19917294565 | et@chemextension.com | China | 5061 | 58 |
| Lianhe Aigen Pharmatech Co.,Ltd. | 18918657159 | sales-Aigen@lianhetech.com | China | 2998 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 38923 | 58 |
| Shandong Dayou Pharmaceutical Research and Development Co., Ltd. | hanfangpharma@126.com 15165037910 | hanfangpharma@126.com | China | 25800 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42052 | 58 |
