ChemicalBook >> CAS DataBase List >>Bis(cyclohexanone)oxaldihydrazone
Bis(cyclohexanone)oxaldihydrazone
- CAS No.
- 370-81-0
- Chemical Name:
- Bis(cyclohexanone)oxaldihydrazone
- Synonyms
- CUPRIZONE;CUPRIZON;Cuprizane;CUPRIZON 1;CUPRIZON I;CUPRIZONE I;CUPFERAZONE;Cuprizonl,98%;oxaldihydrazone;Oxalic acid bis
- CBNumber:
- CB3334186
- Molecular Formula:
- C14H22N4O2
- Molecular Weight:
- 278.35
- MDL Number:
- MFCD00001659
- MOL File:
- 370-81-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-20 23:19:27
| Melting point | 210-214 °C(lit.) |
|---|---|
| Boiling point | 421.17°C (rough estimate) |
| Density | 1.0823 (rough estimate) |
| bulk density | 150kg/m3 |
| refractive index | 1.6200 (estimate) |
| storage temp. | 2-8°C |
| solubility | acetic acid: 50mg/mL, colorless to very faintly brown |
| form | Powder |
| pka | 10.78±0.20(Predicted) |
| color | White |
| Water Solubility | Soluble in alcohol. Insoluble in water. |
| BRN | 2388004 |
| InChI | 1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20) |
| InChIKey | DSRJIHMZAQEUJV-UHFFFAOYSA-N |
| SMILES | O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2 |
| CAS DataBase Reference | 370-81-0(CAS DataBase Reference) |
| FDA UNII | 5N16U7E0AO |
| EPA Substance Registry System | Ethanedioic acid, bis(cyclohexylidenehydrazide) (370-81-0) |
| UNSPSC Code | 41116105 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 21/22 | |||||||||
| Safety Statements | 24/25-2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | RO2520000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29280090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Bis(cyclohexanone)oxaldihydrazone price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 14690 | Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 370-81-0 | 25g | $95.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 14690 | Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 370-81-0 | 100g | $278 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1.01841 | Oxalic acid bis (cyclohexylidene hydrazide) GR for analysis (reagent for copper) | 370-81-0 | 25g | $194 | 2022-05-15 | Buy |
| TCI Chemical | B0476 | Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | 370-81-0 | 1g | $53 | 2026-04-30 | Buy |
| TCI Chemical | B0476 | Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | 370-81-0 | 25g | $192 | 2026-04-30 | Buy |
Bis(cyclohexanone)oxaldihydrazone Chemical Properties, Uses, Production
Chemical Properties
white powder
Uses
Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.
Definition
ChEBI: Cuprizon is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Biological Activity
Bis(cyclohexanone)oxaldihydrazone (Cuprizone) is a copper chelator. It results in oligodendroglial cell death, thereby leading to demyelination, astrogliosis and microglia activation. Cuprizone is widely used to study mitochondrial dysfunction-associated primary demyelination and remyelination in the corpus callosum.
Safety Profile
Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also OXALATES.
Bis(cyclohexanone)oxaldihydrazone Preparation Products And Raw materials
Bis(cyclohexanone)oxaldihydrazone Suppliers
Global Suppliers ( 273)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from Bis(cyclohexanone)oxaldihydrazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-07 | Bis(cyclohexanone)oxaldihydrazone
370-81-0
|
1kg | 99%min | 20tons | HANGZHOU HAILAN CHEMICAL CO.,LTD. | ||
 |
2026-07-20 | Cuprizone
370-81-0
|
$35.00 | 99.94% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-03-06 | Bis(cyclohexanone)oxaldihydrazone
370-81-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Bis(cyclohexanone)oxaldihydrazone
370-81-0
- $0.00
- 99%min
- HANGZHOU HAILAN CHEMICAL CO.,LTD.
-
- Cuprizone
370-81-0
- $35.00
- 99.94%
- TargetMol Chemicals Inc.
-
- Bis(cyclohexanone)oxaldihydrazone
370-81-0
- $1.00
- 99%
- Career Henan Chemical Co
370-81-0 (Bis(cyclohexanone)oxaldihydrazone) Related Search:
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CUPRIZON
CUPRIZONE
370-81-0
C14H22N4O2
