ChemicalBook >> CAS DataBase List >>Bis(cyclohexanone)oxaldihydrazone
Bis(cyclohexanone)oxaldihydrazone
- CAS No.
- 370-81-0
- Chemical Name:
- Bis(cyclohexanone)oxaldihydrazone
- Synonyms
- CUPRIZON;CUPRIZONE;Cuprizane;CUPRIZON 1;CUPRIZON I;CUPRIZONE I;CUPFERAZONE;Cuprizonl,98%;oxaldihydrazone;Oxalic acid bis
- CBNumber:
- CB3334186
- Molecular Formula:
- C14H22N4O2
- Molecular Weight:
- 278.35
- MDL Number:
- MFCD00001659
- MOL File:
- 370-81-0.mol
Last updated:2026-02-25 19:46:50
| Product description | Number | Pack Size | Price |
| Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 14690 | 25g | $90.9 |
| Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 14690 | 100g | $264 |
| Oxalic acid bis (cyclohexylidene hydrazide) GR for analysis (reagent for copper) | 1.01841 | 25g | $194 |
| Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | B0476 | 1g | $53 |
| Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | B0476 | 25g | $192 |
| Melting point | 210-214 °C(lit.) |
|---|---|
| Boiling point | 421.17°C (rough estimate) |
| bulk density | 150kg/m3 |
| Density | 1.0823 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | 2-8°C |
| solubility | acetic acid: 50mg/mL, colorless to very faintly brown |
| pka | 10.78±0.20(Predicted) |
| form | Powder |
| color | White |
| Water Solubility | Soluble in alcohol. Insoluble in water. |
| BRN | 2388004 |
| InChI | 1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20) |
| InChIKey | DSRJIHMZAQEUJV-UHFFFAOYSA-N |
| SMILES | O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2 |
| CAS DataBase Reference | 370-81-0(CAS DataBase Reference) |
| FDA UNII | 5N16U7E0AO |
| EPA Substance Registry System | Ethanedioic acid, bis(cyclohexylidenehydrazide) (370-81-0) |
| UNSPSC Code | 41116105 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 21/22 | |||||||||
| Safety Statements | 24/25-2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | RO2520000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29280090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Bis(cyclohexanone)oxaldihydrazone price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 14690 | Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 370-81-0 | 25g | $90.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | 14690 | Bis(cyclohexanone)oxaldihydrazone for spectrophotometric det. of Cu, ≥99.0% | 370-81-0 | 100g | $264 | 2025-07-31 | Buy |
| Sigma-Aldrich | 1.01841 | Oxalic acid bis (cyclohexylidene hydrazide) GR for analysis (reagent for copper) | 370-81-0 | 25g | $194 | 2022-05-15 | Buy |
| TCI Chemical | B0476 | Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | 370-81-0 | 1g | $53 | 2025-07-31 | Buy |
| TCI Chemical | B0476 | Bis(cyclohexanone) Oxalyldihydrazone >98.0%(T) | 370-81-0 | 25g | $192 | 2025-07-31 | Buy |
Bis(cyclohexanone)oxaldihydrazone Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.
Definition
ChEBI: Cuprizon is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Biological Activity
Bis(cyclohexanone)oxaldihydrazone (Cuprizone) is a copper chelator. It results in oligodendroglial cell death, thereby leading to demyelination, astrogliosis and microglia activation. Cuprizone is widely used to study mitochondrial dysfunction-associated primary demyelination and remyelination in the corpus callosum.
Safety Profile
Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also OXALATES.
Bis(cyclohexanone)oxaldihydrazone Preparation Products And Raw materials
Bis(cyclohexanone)oxaldihydrazone Suppliers
Global( 264)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 12272 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49964 | 58 |
View Lastest Price from Bis(cyclohexanone)oxaldihydrazone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-25 | Cuprizone
370-81-0
|
US $35.00 / g | ≥98% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-02-24 | Bis(cyclohexanone)oxaldihydrazone
370-81-0
|
US $0.00 / kg | 1kg | 99%min | 20tons | HANGZHOU HAILAN CHEMICAL CO.,LTD. | |
 |
2020-03-06 | Bis(cyclohexanone)oxaldihydrazone
370-81-0
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Cuprizone
370-81-0
- US $35.00 / g
- ≥98%
- TargetMol Chemicals Inc.
-
- Bis(cyclohexanone)oxaldihydrazone
370-81-0
- US $0.00 / kg
- 99%min
- HANGZHOU HAILAN CHEMICAL CO.,LTD.
-
- Bis(cyclohexanone)oxaldihydrazone
370-81-0
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
370-81-0(Bis(cyclohexanone)oxaldihydrazone)Related Search:
DICYCLOHEXANONE OXALYLDIHYDRAZONE
CUPFERAZONE
CUPRIZON
CUPRIZON 1
CUPRIZONE
CUPRIZONE I
CUPRIZON I
BIS(CYCLOHEXANONE) OXALDIHYDRAZONE
BISCYCLOHEXANONE OXALYLDIHYDRAZONE
BIS(CYCLOHEXYLIDENE)OXALODIHYDRAZIDE
N,N-oxalylbis(cyclohexanone hydrazone)
oxalic bis(cyclohexylidenehydrazide)
Oxalic acid bis (cyclohexylidene hydrazide) GR for analysis (reagent for copper)
Chromium(III) Ionophore III
BIS-CYCLOHEXANONE OXALDIHYDRAZONECRYSTAL LINE
6-CHLORO-BENZOXAZOL-2(3H)-ONE, PESTANAL
BisCyclohexanoneOxalylDihydrazideGr
Bis(cyclohexanone)oxaldihydrazone=CuprizonI
Cuprizonl,98%
Dicyclohexanoneoxalydihydrazone
Cuprizon, Cuprizone, Oxalic acid bis(cyclohexylidenehydrazide)
N,N'-Bis(cyclohexylideneamino)oxamide
Cupferazone
Cuprizone
OXALIC ACID BIS (CYCLOHEXYLIDENE HYDRAZI
Cuprizane
Oxalic acid bis[N'-(cyclohexylidene) hydrazide]
Oxalic acid di(N'-cyclohexylidene hydrazide)
Oxalic acid bis(cyclohexylidenehydrazide),98%
oxaldihydrazone
Oxalybis(cyclohexylidene hydrazone) biscyclohexanone
Bis(cyclohexanone)ox
Oxalyl bis(cyclohexylidene hydrazone)
Oxalic acid bis
BIS-CYCLOHEXANONE OXALDIHYDRAZONE, 98%BIS-CYCLOHEXANONE OXALDIHYDRAZONE, 98%BIS-CYCLOHEXANONE OXALDIHYDRAZONE, 98%
Ethanedioic acid,1,2-bis(2-cyclohexylidenehydrazide)
Bis(cyclohexanone)oxalyldihydrazone, AR
biscyclohexanone
biscyclohexanoneoxadihydrazone
Dicyclohexanoneoxalyldihydrazo
dicyclohexanoneoxalyldihydrozone
ethanedioicacid,bis(cyclohexylidenehydrazide)
Oxalybis(cyclohexylidene hydrazone)
OXALIC ACID BIS(CYCLOHEXYLIDENEHYDRAZIDE)
TIMTEC-BB SBB008866
Bis(cyclohexanone)oxaldihydrazone, 98%, for spectrophotometric det. of Cu
Bicyclic cyclohexanone oxalyl dihydrazone
Bis(cyclohexanone)oxalyldihydrazone, 98.0%
N'1,N'2-dicyclohexylideneoxalohydrazide
Bis(cyclohexanone)oxaldihydrazone, for spectrophotoMetric det. of Cu
1,?2-?bis(2-?cyclohexylidenehydra?zide) Ethanedioic acid
Bis(cyclohexanone)oxaldihydrazone,AR
Bis(cyclohexanone) oxaldihydrazone, GR 99%
BIS CYCLOHEXANONE OXALYL DIHYDRAZIDE AR
N'1, N'2-Oxalazide (cyclohexylhydrazine)
Dicyclohexanone oxadiazole
Bis-Cyclohexanone Oxalyl Dihydrazide 99% AR
370-81-0
C14H22N4O2
