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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole structure

CAS No.: 124750-53-4

Chemical Name:: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

Synonyms: TTMB;5-(4;ENTERPRISESTANDARD;Losartan Impurity 9;Olmesartan TTMB impurity;5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methyl-2-biphenylyl)-1-trityl-1H-tetrazole;Olmesartan Medoxomil Impurity 24（Losartan Impurity 9）;N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE

CBNumber:: CB3438158

Molecular Formula:: C33H26N4

Molecular Weight:: 478.59

MDL Number:: MFCD00665220

MOL File:: 124750-53-4.mol

MSDS File:: SDS

Last updated:2026-05-28 06:31:54

Product description	Number	Pack Size	Price
5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole	093682	250.00mg	$341
5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole	093682	1.00g	$756
5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	CD12169364	1g	$248
5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	CD12169364	5g	$743
5-(4'-methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	CM132151	1g	$234
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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Properties

Melting point	166-169 °C(Solv: ethyl acetate (141-78-6); dichloromethane (75-09-2))
Boiling point	681.6±65.0 °C(Predicted)
Density	1.13±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly)
form	Solid
pka	0.30±0.10(Predicted)
color	Off-White
InChI	InChI=1S/C33H26N4/c1-25-21-23-26(24-22-25)30-19-11-12-20-31(30)32-34-35-36-37(32)33(27-13-5-2-6-14-27,28-15-7-3-8-16-28)29-17-9-4-10-18-29/h2-24H,1H3
InChIKey	ZSBYTGRKIKIRRJ-UHFFFAOYSA-N
SMILES	N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(C)C=C2)=NN=N1
CAS DataBase Reference	124750-53-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Danger
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	093682	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole	124750-53-4	250.00mg	$341	2026-05-18	Buy
Matrix Scientific	093682	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole	124750-53-4	1.00g	$756	2026-05-18	Buy
Crysdot	CD12169364	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	124750-53-4	1g	$248	2026-05-27	Buy
Crysdot	CD12169364	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	124750-53-4	5g	$743	2026-05-27	Buy
Chemenu	CM132151	5-(4'-methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 97%	124750-53-4	1g	$234	2026-05-26	Buy

Product number	Packaging	Price	Buy
093682	250.00mg	$341	Buy
093682	1.00g	$756	Buy
CD12169364	1g	$248	Buy
CD12169364	5g	$743	Buy
CM132151	1g	$234	Buy

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Chemical Properties,Uses,Production

Chemical Properties

Off-white Solid

Uses

An intermediate in the preparation of labelled Candesartan.

Uses

5-(4''-Methyl-[1,1''-biphenyl]-2-yl)-1-trityl-1H-tetrazole is a reactant in the synthesis of anti-microbial agents.

Synthesis

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is prepared by the reaction of trityl chloride and 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl. The specific synthesis steps are as follows:
Dissolve compound 2 (200 g) with stirring at 40°C 700mL of acetone, Aqueous sodium hydroxide solution (40.67 g sodium hydroxide dissolved in 160 mL water) is added, Continue stirring for 1h, A solution of triphenylchloromethane in acetone (270.8 g of triphenylmethyl chloride dissolved in 800 mL of acetone) was initially added dropwise. The solid was added dropwise and gradually evolved into a white turbid liquid. The reaction was monitored by TLC until it was completely filtered off and washed with water to give a solid as intermediate 3. The solid was blow dried at 50°C to give white intermediate 3 (385 g), yield: 95.2%, HPLC: 99.44%.
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole synthesis

References

[1] Patent: WO2013/78237, 2013, A1. Location in patent: Page/Page column 111; 112
[2] Patent: CN107935957, 2018, A. Location in patent: Paragraph 0020; 0040-0042
[3] Synthetic Communications, 2008, vol. 38, # 20, p. 3577 - 3581
[4] Journal of Chemical Sciences, 2011, vol. 123, # 4, p. 393 - 401
[5] Archiv der Pharmazie, 2016, vol. 349, # 12, p. 934 - 943

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Preparation Products And Raw materials

Raw materials

Triphenylmethyl Chloride 5-[2-(4'-METHYLBIPHENYL)]TETRAZOLE Acetone Water Sodium hydroxide

Preparation Products

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Suppliers

Global( 186)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3004	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32997	60
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6339	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5898	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Zhengzhou Alfa Chemical Co.,Ltd	+86-18530059196	sale04@alfachem.cn	China	9636	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23504	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Xiamen AmoyChem Co., Ltd	58
Shandong chuangyingchemical Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58
ANHUI WITOP BIOTECH CO., LTD	58

View Lastest Price from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-12	Olmesartan Medoxomil Impurity 19 124750-53-4	10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2025-04-04	5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2020-05-10	5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4	1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd

Olmesartan Medoxomil Impurity 19
124750-53-4
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
98%
Henan Aochuang Chemical Co.,Ltd.

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
99.0%
Shaanxi Dideu Medichem Co. Ltd

124750-53-4(5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole)Related Search:

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 5-[4'-METHYL (1,1'-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE 5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole N-(Triphenylmethyl)-5-(4'-Methylbiphenyl-2-Yl-)Tetrazole (Ttmb) Olmesartan TTMB impurity 1-[2-(diphenylmethyl)phenyl]-5-[2-(4-methylphenyl)phenyl]tetrazole Losartan Impurity 9 n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE 5-(4'-Methyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 5-[4''-METHYL (1,1''-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE 98.5+% N-TriphenylMethyl-5-[4'-Methylbiphenyl-2-yl]tetrazole-d4 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole ENTERPRISESTANDARD 5-(5-Methyl-2-phenylphenyl)-1-(triphenylMethyl)-1H-1,2,3,4-tetrazole Losartan IMpurity (5-(4'-Methylbiphenyl-2-yl)-1-Trityl-1H-Tetrazole) TTMB Olmesartan Medoxomil impurity 8/Olmesartan TTMB Impurity/5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 1H-Tetrazole, 5-(4'-methyl[1,1'-biphenyl]-2-yl)-1-(triphenylmethyl)- Losartan Impurity （5-?(4’-?Methyl-?[1,?1’-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole） 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole USP/EP/BP 5-?(4'-?Methyl-?[1,?1'-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole DISCONTINUED. Please see T889170 Olmesartan Medoxomil Impurity 24（Losartan Impurity 9） 5-(4'-Methyl[1,1'-biphenyl]-2-yl)-1-(triphenylmethyl)-1H-tetrazole 5-(4 5-(4'-Methyl-2-biphenylyl)-1-trityl-1H-tetrazole N-(Triphenylmethyl)-5-(4'-Methylbiphenyl-2-yl) Tetrazole 5-(4'-METHYL-[1,1'-BIPHENYL]-2-YL)-1-TRITYL-1H- TETRAZOLE / PENULTIMATE IMPURITY 5-(4'-Methyl-biphenyl-2-yl)-1-(triphenylmethyl)-1H-tetrazole 124750-53-4 C33H22D4N4 C34H29N4 C33H26N4 Biphenyl & Diphenyl ether API intermediates Hypertension