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Trityl olmesartan

Trityl olmesartan structure

CAS No.: 144690-92-6

Chemical Name:: Trityl olmesartan

Synonyms: TRITYL OLMESARTAN MEDOXOMIL;Atila;Folusen;OMSTint-G;Trityl olmesartan;OlMesartan trityl;Trithyl Olmesartan;Olmesartan Impurity D;Olmesartan medoxomil D;Olmesartan Medoxomil-4

CBNumber:: CB8511430

Molecular Formula:: C48H44N6O6

Molecular Weight:: 800.9

MDL Number:: MFCD09954745

MOL File:: 144690-92-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:46:47

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Trityl olmesartan Properties

Melting point	104-106°C
Boiling point	960.0±75.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMF: 1 mg/ml,DMSO: 1 mg/ml
pka	13.21±0.29(Predicted)
form	A solid
Appearance	White to off-white Solid
InChIKey	IJOPLMOXIPGJIJ-UHFFFAOYSA-N
SMILES	C1(CCC)N(CC2=CC=C(C3=CC=CC=C3C3N(C(C4=CC=CC=C4)(C4=CC=CC=C4)C4=CC=CC=C4)N=NN=3)C=C2)C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(O)(C)C)N=1
CAS DataBase Reference	144690-92-6(CAS DataBase Reference)
FDA UNII	8591TIT360

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H315-H319-H228
Precautionary statements	P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
REACH Registrations	Active

Trityl olmesartan price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	34854	Tritylolmesartan Medoxomil ≥98%	144690-92-6	5g	$36	2026-04-30	Buy
Cayman Chemical	34854	Tritylolmesartan Medoxomil ≥98%	144690-92-6	10g	$61	2026-04-30	Buy
Cayman Chemical	34854	Tritylolmesartan Medoxomil ≥98%	144690-92-6	25g	$120	2026-04-30	Buy
Cayman Chemical	34854	Tritylolmesartan Medoxomil ≥98%	144690-92-6	100g	$219	2026-04-30	Buy
Usbiological	292217	4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazo-5-carboxylate (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl	144690-92-6	5mg	$327	2026-06-03	Buy

Product number	Packaging	Price	Buy
34854	5g	$36	Buy
34854	10g	$61	Buy
34854	25g	$120	Buy
34854	100g	$219	Buy
292217	5mg	$327	Buy

Trityl olmesartan Chemical Properties, Uses, Production

Chemical Properties

Off-White to White Powder

Uses

Olmesartan medoxomil analog as angiotensin II antagonist.

Uses

Olmesartan medoxomil intermediate.

Uses

N-1 Trityl Olmesartan Medoxomil (Olmesartan EP Impurity D) is an olmesartan medoxomil intermediate.

Synthesis

This describes steps for preparing a trityl-protected intermediate in olmesartan medoxomil synthesis:
1. An imidazole ester derivative is alkylated with a trityl-protected biphenyltetrazole bromide in acetone with KCO/phase-transfer catalyst. Work-up gives an intermediate.
2. This intermediate is further alkylated with a side-chain bromide in the presence of acetone/KCO/KI. Treatment with toluene/methanol precipitates trityl olmesartan ester.

Trityl olmesartan synthesis

Synthesis of Trityl olmesartan from 1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester and 4-Cloromethyl-5-methyl-1,3-dioxol-2-one

Trityl olmesartan Preparation Products And Raw materials

Raw materials

1-benzyl-5-phenyltetrazole 1114761-92-0 Trityl olMesartan acid 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-4-carboxylate

Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 4-Bromomethyl-5-methyl-1,3-dioxol-2-one 1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester 4-Cloromethyl-5-methyl-1,3-dioxol-2-one

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Preparation Products

Triphenylmethanol

Trityl olmesartan Suppliers

Global Suppliers ( 292)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
XiaoGan ShenYuan ChemPharm co,ltd	15527621225; 15527621225	1791901229@qq.com	China	6741	52
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.	0523-82837785 13914525028	info@jszchg.com	China	244	60
Wuhan Fortuna Chemical Co., Ltd	027-59207852 13308628970	buy@fortunachem.com	China	2689	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4773	55
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7993	58
Valiant Co., Ltd.	0535-6101880	liutao@valiant-cn.com	China	279	60
Hubei XinyuanShun Chemical Co., Ltd.	13971561712, 13995564702, 027-50664929	hbeixys2001@163.com	China	3110	55

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Adamas Reagent, Ltd.	59
Chemsky（shanghai）International Co.,Ltd.	50
XiaoGan ShenYuan ChemPharm co,ltd	52
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.	60
Wuhan Fortuna Chemical Co., Ltd	58
Guangzhou Isun Pharmaceutical Co., Ltd	55
TargetMol Chemicals Inc.	58
Valiant Co., Ltd.	60
Hubei XinyuanShun Chemical Co., Ltd.	55

View Latest Price from Trityl olmesartan manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	Trityl olmesartan 144690-92-6		1KG	98%min	1000kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-08-20	Trityl olmesartan 144690-92-6	$1.10	1g	99.0% Min	100 Tons	Dideu Industries Group Limited
2026-06-30	Trityl olmesartan 144690-92-6		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

Trityl olmesartan
144690-92-6
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Trityl olmesartan
144690-92-6
$1.10
99.0% Min
Dideu Industries Group Limited

Trityl olmesartan
144690-92-6
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

Trityl olmesartan Spectrum

Trityl olmesartan(144690-92-6)¹HNMR

144690-92-6 (Trityl olmesartan) Related Search:

Triphenylphosphine Triphenylbismuth OlMesartan interMediate iMpurity II 3,6-Dihydro-6,6-diMethyl-2-propyl-3-[[2'-[2-(triphenylMethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-4H-furo[3,4-d]iMidazol-4-one Olmesartan medoxomil impurity I

diethyl 2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-dicarboxylate OlMesartan MedoxoMil iMpurity V N-Trityl Olmesartan Ethyl Ester Trityl olMesartan MedoxoMil iMpurity III Olmesartan

Trityl olmesartan 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate 4-Hydroxymethyl-1,3-dioxolan-2-one n-Butyl OlMesartan MedoxoMil

5-(Hydroxymethyl)-1H-imidazole-4-carboxylic acid methyl ester N-Trityl olmesartan-d6 ethyl ester 4-Isopropyl-2-methylimidazole

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Trityl olmesartan 5-Methoxy – 2-oxo-1,3-dioxol - 4 - yl ) methyl - 4 - (1-hydroxy -1 - methylethyl -2 propyl-1- (2 –(2-triphenylmethyl ) -2H – tetrazole -5 – yl ) biphenyl -4-yl ) methyl ) -1H-imidazole – 5 – carboxylate TRIPHENYL METHYL OLMESARTAN OMSTint-G Olmesartan USP Impurity D 3-((3'-carbamoyl-[1,1'-biphenyl]-3-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylic acid Olmesartan Medoxomil impurity 13/ N1-Trityl Olmesartan Medoxomil/(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(prop-1-en-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate Olmesartan Medoxomil-4 Olmesartan medoxomil D Olmesartan1 Impurity 31 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1h-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester TRITYL OLMESARTAN MEDOXOMIL (99.5%) 1H-Imidazole-5-carboxylic acid,4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester Tritylolmesartan(ForOlmesartan) N-Triphenyl Methyl Omesartan InterMediate of OlMesartan MedoxoMil OlMesartan EP IMp D (Trityl OlMesartanMedoxoMil) OlMesartan MedoxoMil N1-Trityl IMpurity N1-Trityl OlMesartan MedoxoMil (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate Trityl olmesartan medoxomil, >=98% 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester OlMesartan trityl Olmesartan MedoxomiI Impurity D (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate TRITYL OLMESARTAN MEDOXOMIL CAS 144690-92-6 Trityl olmesartan ISO 9001：2015 REACH Azilsartan medoxomil impurity238 Olmesartan Medoxomil Impurity16 5-Methoxy-2-oxo-1,3-dioxol-4-yl)methyl-4-(1-hydroxy-1-methylethyl) TIANFU-CHEM - Trityl olmesartan Atila Folusen Olmesartan Impurity D (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidarde-5-carboxylate Olmesartan ester impurity D (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate Trithyl Olmesartan N1-Trityl Olmesartan Medoxomil 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2’-[1- (triphenylmethyl)-1H-tetrazol-5-yl][1,1’-biphenyl]-4-yl]methyl]- 1H-Imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4- yl)Methyl Ester (5-methyl-2-oxo-1,3-dioxolen-4-yl) methyl-4-1 (1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-trityltetrazol-5-yl)phenyl] phenyl} methylimidazole-5-carboxylate (5-methyl-2-oxo-1,3-dioxol-4-yl) 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1′-biphenyl]-4-yl]methyl]- 1H-Imidazole-5-carboxylic acid (Trityl Olmesartan) Tritylolmesartan medoxomil (OR) (5-methyl-2-oxo-1,3-dioxol-4- yl)methyl 5-(2-hydroxypropan-2-yl)- 2-propyl-3-[[4-[2-(1-trityltetrazol-5- yl)phenyl]phenyl]methyl]imidazole-4- carboxylate Trityl olmesartan medoxomil (Olmesartan Medoxomi Impurity) (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate Triphenylolmesartanester(OM2) Trityl Olmesartan Medoxomil (Intermediate of Olmesartan medoxomil) TRITYL OLMESARTAN MEDOXOMIL 144690-92-6 C48H44N6O6 INTERMEDIATESOF (intermediate of olmesartan) Bases & Related Reagents Drug Analogues Heterocycles Intermediates & Fine Chemicals Nucleotides Pharmaceuticals LFQ