ChemicalBook >> CAS DataBase List >>Compound 23

Compound 23

Compound 23 structure

CAS No.: 1062169-46-3

Chemical Name:: Compound 23

Synonyms: WYE-23;Compound 23;mTOR Inhibitor, WYE-23;methyl 4-(6-(4-[(cyclopropylcarbamoyl)amino]phenyl)-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate;4-[6-[4-[[(cyclopropylamino)carbonyl]amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylicacid,methylester;1-Piperidinecarboxylic acid, 4-[6-[4-[[(cyclopropylamino)carbonyl]amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-, methyl ester

CBNumber:: CB34666368

Molecular Formula:: C26H32N8O4

Molecular Weight:: 520.58

MDL Number:

MOL File:: 1062169-46-3.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:07

Request For Quotation

Compound 23 Properties

Density	1.52±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	White powder solid.
pka	13.53±0.20(Predicted)

Compound 23 price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21199	WYE-23 ≥98%	1062169-46-3	500μg	$49	2026-04-30	Buy
Cayman Chemical	21199	WYE-23 ≥98%	1062169-46-3	1mg	$93	2026-04-30	Buy
Cayman Chemical	21199	WYE-23 ≥98%	1062169-46-3	5mg	$376	2026-04-30	Buy
Cayman Chemical	21199	WYE-23 ≥98%	1062169-46-3	10mg	$655	2026-04-30	Buy
Biosynth	BC178927	Compound 23	1062169-46-3	1mg	$317.63	2026-06-04	Buy

Product number	Packaging	Price	Buy
21199	500μg	$49	Buy
21199	1mg	$93	Buy
21199	5mg	$376	Buy
21199	10mg	$655	Buy
BC178927	1mg	$317.63	Buy

Compound 23 Chemical Properties, Uses, Production

Uses

mTOR inhibitor WYE-23 is a mTOR inhibitor, and IC50 is 0.45 nM. It is selective to PI3Kα and IC50 is 661 nM. mTOR inhibitor WYE-23 has antitumor activity[1][2].

References

[1] Nikola P. Pavletich et al. mTOR CRYSTALS AND MODULATORS. WO2014176281A1.2014-10-30.
[2] Zask A, et al. ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines. J Med Chem. 2009 Aug 27;52(16):5013-6. DOI:10.1021/jm900851f

Compound 23 Preparation Products And Raw materials

Raw materials

Preparation Products

Compound 23 Suppliers

Global Suppliers ( 16)

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774 400-920-5774	sales@glpbio.cn	China	6705	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
BOC Sciences	65
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
TargetMol Chemicals Inc.	58

1062169-46-3 (Compound 23) Related Search:

N-[4-[5-(1,3-Benzodioxol-5-yl)-3-methoxy-1H-1,2,4-triazol-1-yl]phenyl]-2-(phenylthio)acetamide NSC 23766 tetrahydrochloride C2 ceramide PD 173074 NSC697923

MIF Antagonist, ISO-1 GSK-3β Inhibitor XVIII Pictilisib JNJ-10198409 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

Motesanib Chk2 Inhibitor Trolox MMP-9 INHIBITOR I ERK Inhibitor

Compound 28 Glycogen Phosphorylase Inhibitor 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

1of4

Compound 23 mTOR Inhibitor, WYE-23 methyl 4-(6-(4-[(cyclopropylcarbamoyl)amino]phenyl)-4-morpholin-4-yl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate WYE-23 1-Piperidinecarboxylic acid, 4-[6-[4-[[(cyclopropylamino)carbonyl]amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-, methyl ester 4-[6-[4-[[(cyclopropylamino)carbonyl]amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylicacid,methylester 1062169-46-3 C26H32N8O4