ChemicalBook >> CAS DataBase List >>(S)-1-Cbz-3-pyrrolidinol 95
(S)-1-Cbz-3-pyrrolidinol 95
- CAS No.
- 100858-32-0
- Chemical Name:
- (S)-1-Cbz-3-pyrrolidinol 95
- Synonyms
- Benzyl (S)-3-hydroxypyrrolidine-1-carboxylate;CAS:100858-32-0;(S)-1-Cbz-3-pyrrolodonol95;(S)-N-Cbz-3-hydroxypyrroline;(S)-(+)-1-Cbz-3-pyrrolidinol;(S)-1-Cbz-3-pyrrolidinol 95;N-Cbz-3(S)-hydroxypyrrolidine;S-1-N-CBZ-3- hydroxy-pyrroline;(S)-1-Cbz-3-hydroxypyrrolidine;(S)-N-CBZ-3-HYDROXYPYRROLIDINE
- CBNumber:
- CB3505445
- Molecular Formula:
- C12H15NO3
- Molecular Weight:
- 221.25
- MDL Number:
- MFCD07784363
- MOL File:
- 100858-32-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:52:06
| Melting point | 71-77 °C |
|---|---|
| Boiling point | 370.7±42.0 °C(Predicted) |
| Density | 1.263±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | 14.72±0.20(Predicted) |
| Appearance | White to off-white Solid |
| optical activity | [α]20/D +21°, c = 1 in chloroform |
| InChI | InChI=1S/C12H15NO3/c14-11-6-7-13(8-11)12(15)16-9-10-4-2-1-3-5-10/h1-5,11,14H,6-9H2/t11-/m0/s1 |
| InChIKey | MBLJFGOKYTZKMH-NSHDSACASA-N |
| SMILES | N1(C(OCC2=CC=CC=C2)=O)CC[C@H](O)C1 |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-36/37/38 | |||||||||
| Safety Statements | 26-36-45-25 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
(S)-1-Cbz-3-pyrrolidinol 95 price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 654663 | (S)-(+)-1-Cbz-3-pyrrolidinol 95% | 100858-32-0 | 1g | $69.2 | 2023-01-07 | Buy |
| Sigma-Aldrich | 654663 | (S)-(+)-1-Cbz-3-pyrrolidinol 95% | 100858-32-0 | 5g | $259 | 2023-01-07 | Buy |
| TCI Chemical | C2453 | (S)-1-Carbobenzoxy-3-pyrrolidinol >97.0%(GC) | 100858-32-0 | 1g | $16 | 2021-12-16 | Buy |
| TCI Chemical | C2453 | (S)-1-Carbobenzoxy-3-pyrrolidinol >97.0%(GC) | 100858-32-0 | 5g | $48 | 2021-12-16 | Buy |
| Usbiological | 270523 | S-1-Carbobenzoxy-3-pyrrolidinol Asreported | 100858-32-0 | 500mg | $306 | 2026-06-03 | Buy |
(S)-1-Cbz-3-pyrrolidinol 95 Chemical Properties, Uses, Production
Chemical Properties
White to off-white crystal powder or solid
Synthesis
130312-02-6
100858-32-0
General procedure for the synthesis of benzyl (S)-3-hydroxypyrrolidine-1-carboxylate using N-Cbz-3-pyrrolidone as starting material: a reaction mixture containing 200 mM substrate, 1 mM NAD+, 5% (v/v) 2-propanol, and 10 mg of the crude enzyme READH was prepared in 1 mL of potassium phosphate buffer (100 mM, pH 7.0) and warmed at 50 °C. For ChKRED20, 40% (v/v) 2-propanol was used and the reaction was carried out at 40°C. The reaction progress was monitored by TLC and the reaction was terminated by extraction with methyl tert-butyl ether (1 mL). The organic phase was dried over anhydrous sodium sulfate and concentrated. Samples were analyzed by chiral HPLC to determine conversion and enantiomeric excess. The final product was purified by silica gel column chromatography and the structure was confirmed by NMR, spin determination and mass spectrometry.
References
[1] Process Biochemistry, 2017, vol. 56, p. 90 - 97
(S)-1-Cbz-3-pyrrolidinol 95 Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global Suppliers ( 180)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hobor Chemical Co., Ltd | 13918007836 | sales@hoborchem.com | China | 423 | 60 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Sichuan Guanghan Bio-Tech Co., Ltd | +86-28-86127071 | info@sino-produce.com | China | 400 | 66 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from (S)-1-Cbz-3-pyrrolidinol 95 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
|
$9.00 | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-04-04 | (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
- $9.00
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
-
- (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- (S)-1-CBZ-3-PYRROLIDINOL 95
100858-32-0
- $1.00
- 99%
- Career Henan Chemical Co
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N-Cbz-3(S)-hydroxypyrrolidine
(S)-1-Benzyloxycarbonyl-3-pyrrolidinol, (S)-1-Carbobenzoxy-3-pyrrolidinol, (S)-N-Z-3-Pyrrolidinol
(S)-1-Cbz-3-hydroxypyrrolidine
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(S)-3-Hydroxy-pyrrolidine-1-carboxylic acid benzyl ester
(S)-(+)-1-Cbz-3-pyrrolidinol
(S)-1-Carbobenzoxy-3-pyrrolidinol >
(S)-1-Carbobenzoxy-3-hydroxypyrrolidine
(S)-(3-hydroxypyrrolidin-1-yl)(phenyl)methanone
Phenylmethyl (3S)-3-hydroxy-1-pyrrolidinecarboxylate
(S)-1-Cbz-3-pyrrolodonol95
CAS:100858-32-0
(S)-(+)-1-Cbz-3-pyrrolidinol
(S)-1-Cbz-3-hydroxypyrrolidine - [H12296]
Benzyl (S)-3-hydroxypyrrolidine-1-carboxylate
(S)-1-Cbz-3-pyrrolidinol 95
100858-32-0
Pyrrole&Pyrrolidine&Pyrroline
