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(S)-1-Boc-2-methylpyrrolidine

(S)-1-Boc-2-methylpyrrolidine Structure
(S)-1-Boc-2-methylpyrrolidine structure
CAS No.
137496-71-0
Chemical Name:
(S)-1-Boc-2-methylpyrrolidine
Synonyms
Zinc04203908;(S)-1-Boc-2-methylpyrrolidine;(S)-N-Boc-2-methylpyrrolidine;(S)-tert-Butyl 2-Methylpyrrolidine-1-carboxylate;Tert-butyl (2s)-2-methylpyrrolidine-1-carboxylate;1,1-Dimethylethyl (2S)-2-methyl-1-pyrrolidinecarboxylate;(S)-2-Methyl-pyrrolidine-1-carboxylic acid tert-butyl ester;(S)-tert-Butyl 2-methylpyrrolidine-1-carboxylateStructural picture;1-Pyrrolidinecarboxylic acid, 2-Methyl-, 1,1-diMethylethyl ester, (2S)-
CBNumber:
CB3702826
Molecular Formula:
C10H19NO2
Molecular Weight:
185.26
MDL Number:
MFCD06858469
MOL File:
137496-71-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:10
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(S)-1-Boc-2-methylpyrrolidine Properties

Boiling point 234.0±9.0 °C(Predicted)
Density 0.962 g/mL at 25 °C
refractive index n20/D 1.444
Flash point 82 °C
storage temp. 2-8°C
pka -1.21±0.40(Predicted)
Appearance Colorless to light yellow Liquid
optical activity Consistent with structure

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)Environment (GHS09)
GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H227-H301-H315-H318-H335-H410
Precautionary statements  P261-P273-P280-P301+P310-P305+P351+P338
Hazard Codes  T,N
Risk Statements  25-37/38-41-50
Safety Statements  26-39-45-61
RIDADR  UN 2810 6.1/PG 3
HazardClass  8, 6.1
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

(S)-1-Boc-2-methylpyrrolidine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 56268 (S)-1-BOC-2-METHYL-PYRROLIDINE 97% 137496-71-0 1G $184 2026-04-30 Buy
AstaTech 56268 (S)-1-BOC-2-METHYL-PYRROLIDINE 97% 137496-71-0 5G $553 2026-04-30 Buy
AstaTech 56268 (S)-1-BOC-2-METHYL-PYRROLIDINE 97% 137496-71-0 10G $829 2026-04-30 Buy
Chem-Impex 41565 (S)-N-Boc-2-methylpyrrolidine ≥95% 137496-71-0 5G $295.54 2026-05-19 Buy
Synthonix B53291 (S)-tert-Butyl 2-methylpyrrolidine-1-carboxylate 97% 137496-71-0 250mg $87 2026-05-06 Buy
Product number Packaging Price Buy
56268 1G $184 Buy
56268 5G $553 Buy
56268 10G $829 Buy
41565 5G $295.54 Buy
B53291 250mg $87 Buy

(S)-1-Boc-2-methylpyrrolidine Chemical Properties, Uses, Production

Synthesis

tert-butyl (2R)-2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylate

132482-10-1

(S)-1-BOC-2-METHYLPYRROLIDINE

137496-71-0

Tert-butyl 2R-methanesulfonyloxymethylpyrrolidine-1-carboxylate (1.6 g, 5.73 mmol) was used as a raw material, and lithium triethylborohydride (1 M solution in THF, 17 mL, 17 mmol) was slowly added to its solution in 10 mL of tetrahydrofuran at 0 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and water and washed sequentially with 0.1 N HCl and saturated saline. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated to give tert-butyl (S)-2-methylpyrrolidine-1-carboxylate as a colorless transparent oil (0.930 g, 88% yield). Its NMR hydrogen spectrum (400 MHz, CDCl3) data were as follows: δ 3.83 (m, 1H), 3.38 (m, 2H), 1.92 (m, 3H), 1.58 (m, 1H), 1.48 (s, 9H), 1.2 (d, J = 8 Hz, 3H).

References

[1] Patent: WO2006/19833, 2006, A1. Location in patent: Page/Page column 61
[2] Tetrahedron Letters, 1995, vol. 36, # 8, p. 1223 - 1226

(S)-1-Boc-2-methylpyrrolidine Preparation Products And Raw materials

Raw materials

(R)-tert-Butyl 2-(tosyloxymethyl)pyrrolidine-1-carboxylate tert-butyl (2R)-2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylate Ethyl acetate Tetrahydrofuran Water
Lithium Triethylborohydride

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Preparation Products

(S)-1-Boc-2-methylpyrrolidine Suppliers

Global Suppliers ( 63)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Sichuan Guanghan Bio-Tech Co., Ltd +86-28-86127071 info@sino-produce.com China 400 66
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4565 58
Chengdu Firster Pharmaceutical Co., Ltd. 028-87078428 028-87074958 chengzhenyong@cdfirster.com China 2580 60
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6959 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
Energy Chemical 61
Sichuan Guanghan Bio-Tech Co., Ltd 66
China DongFan Chemical Co.,LTD 66
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58
Chengdu Firster Pharmaceutical Co., Ltd. 60
Chengdu HuaXia Chemical Reagent Co. Ltd 58
Shanghai Balmxy Pharmaceutical Co., Ltd 55
Amadis Chemical Company Limited 58

View Latest Price from (S)-1-Boc-2-methylpyrrolidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-1-BOC-2-METHYLPYRROLIDINE pictures 2019-07-06 (S)-1-BOC-2-METHYLPYRROLIDINE
137496-71-0
 $2.00 1KG 99% Career Henan Chemical Co

(S)-1-Boc-2-methylpyrrolidine Spectrum

(S)-1-BOC-2-METHYLPYRROLIDINE(137496-71-0)1HNMR

137496-71-0 ((S)-1-Boc-2-methylpyrrolidine) Related Search:

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(S)-N-Boc-2-methylpyrrolidine (S)-2-Methyl-pyrrolidine-1-carboxylic acid tert-butyl ester Zinc04203908 (S)-tert-Butyl 2-Methylpyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylic acid, 2-Methyl-, 1,1-diMethylethyl ester, (2S)- Tert-butyl (2s)-2-methylpyrrolidine-1-carboxylate (S)-tert-Butyl 2-methylpyrrolidine-1-carboxylateStructural picture 1,1-Dimethylethyl (2S)-2-methyl-1-pyrrolidinecarboxylate (S)-1-Boc-2-methylpyrrolidine 137496-71-0 Heterocyclic Compounds