ChemicalBook >> CAS DataBase List >>3,5-Dichloro-4-formyl pyridine

3,5-Dichloro-4-formyl pyridine

CAS No.
136590-83-5
Chemical Name:
3,5-Dichloro-4-formyl pyridine
Synonyms
3,5-DICHLOROISONICOTINALDEHYDE;3,5-dichloropyridine-4-carbaldehyde;3,5-DICHLORO-4-PYRIDINECARBOXALDEHYDE;TIMTEC-BB SBB003785;3,5-Dichloro-4-formyl pyridine;,5-Dichloropyridine-4-carboxaldehyde;3,5-Dichloropyridine-4-carboxaldehyde;3,5-DICHLOROPYRIDINE-4-CARBOXYALDEHYDE;4-PYRIDINECARBOXALDEHYDE, 3,5-DICHLORO-;3,5-Dichloro-4-pyridinecarboxaldehyde 97%
CBNumber:
CB3725131
Molecular Formula:
C6H3Cl2NO
Molecular Weight:
176
MDL Number:
MFCD04039921
MOL File:
136590-83-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:52:10

3,5-Dichloro-4-formyl pyridine Properties

Melting point 75-79 °C (lit.)
Boiling point 242.4±35.0 °C(Predicted)
Density 1.488±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka -0.42±0.10(Predicted)
color White to Brown
InChI 1S/C6H3Cl2NO/c7-5-1-9-2-6(8)4(5)3-10/h1-3H
InChIKey RBFNWOINNIOZKR-UHFFFAOYSA-N
SMILES [H]C(=O)c1c(Cl)cncc1Cl
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933399990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

3,5-Dichloro-4-formyl pyridine price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 572470 3,5-Dichloro-4-pyridinecarboxaldehyde 97% 136590-83-5 5g $236 2026-04-30 Buy
TCI Chemical D5790 3,5-Dichloro-4-pyridinecarboxaldehyde 136590-83-5 1G $18 2026-04-30 Buy
TCI Chemical D5790 3,5-Dichloro-4-pyridinecarboxaldehyde 136590-83-5 5G $53 2026-04-30 Buy
Biosynth FD147096 3,5-Dichloro-4-pyridinecarboxaldehyde 136590-83-5 5g $900 2026-06-04 Buy
Biosynth FD147096 3,5-Dichloro-4-pyridinecarboxaldehyde 136590-83-5 50g $900 2026-06-04 Buy
Product number Packaging Price Buy
572470 5g $236 Buy
D5790 1G $18 Buy
D5790 5G $53 Buy
FD147096 5g $900 Buy
FD147096 50g $900 Buy

3,5-Dichloro-4-formyl pyridine Chemical Properties,Uses,Production

Uses

3,5-Dichloroisonicotinaldehyde is an aldehyde compound that can be synthesized with heteroarylsulfonamides to form heteroarylsulfonylcarboxamides[1].

Synthesis

3,5-Dichloropyridine

2457-47-8

3,5-DICHLORO-4-FORMYL PYRIDINE

136590-83-5

Diisopropylamine (33.6 mL, 0.24 mol) was dissolved in tetrahydrofuran (400 mL) under argon protection and cooled to -65 °C. The solution of 1.6 M n-butyllithium in hexane (156 mL) was added slowly. A hexane solution (156 mL) of 1.6 M n-butyllithium was slowly added. after 20 min, a solution of 3,5-dichloropyridine (29.6 g, 0.20 mol) in tetrahydrofuran (150 mL) was added dropwise, and stirring was continued for 30 min. Subsequently, a tetrahydrofuran (50 mL) solution of dimethylformamide (23.2 mL, 0.30 mol) was added, kept at a constant temperature and stirred for 1 hour. The reaction mixture was poured into 5% aqueous ammonium chloride solution (1,000 mL) and extracted with ethyl acetate. The organic layer was washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford 3,5-dichloropyridine-4-carbaldehyde (27.2 g, 77% yield).1H-NMR (CDCl3) δ: 8.63 (2H, s), 10.44 (1H, s).

References

[1] Patent: US5935977, 1999, A
[2] Patent: EP1270577, 2003, A1

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View Lastest Price from 3,5-Dichloro-4-formyl pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-DICHLORO-4-FORMYL PYRIDINE pictures 2026-08-20 3,5-DICHLORO-4-FORMYL PYRIDINE
136590-83-5
$1.10 1g 99.00% 100 Tons min Dideu Industries Group Limited
3,5-DICHLORO-4-FORMYL PYRIDINE pictures 2026-08-13 3,5-DICHLORO-4-FORMYL PYRIDINE
136590-83-5
1G 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
3,5-DICHLORO-4-FORMYL PYRIDINE pictures 2025-04-04 3,5-DICHLORO-4-FORMYL PYRIDINE
136590-83-5
1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
3,5-Dichloropyridine-4-carboxaldehyde, 3,5-Dichloro-4-formylpyridine 3,5-Dichloro-4-pyridinecarboxaldehyde 97% TIMTEC-BB SBB003785 3,5-DICHLORO-4-PYRIDINECARBOXALDEHYDE 3,5-DICHLOROPYRIDINE-4-CARBOXYALDEHYDE 3,5-Dichloropyridine-4-carboxaldehyde 4-PYRIDINECARBOXALDEHYDE, 3,5-DICHLORO- ,5-Dichloropyridine-4-carboxaldehyde 4-PYRIDINECARBOXALDEHYDE, 3,5-DICHLORO- (9CI) 3,5-dichloropyridine-4-carbaldehyde 3,5-DICHLORO-4-FORMYL PYRIDINE ISO 9001:2015 REACH 3,5-DICHLOROISONICOTINALDEHYDE 3,5-Dichloro-4-formyl pyridine 136590-83-5 Halogenated Heterocycles Heterocyclic Building Blocks Pyridines Building Blocks Aldehydes Building Blocks C1 to C6 C6Heterocyclic Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Pyridines pharmacetical Pyridine Aldehyde Organohalides C5 to C6 C6 to C7 Carbonyl Compounds Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Organic Building Blocks