TERT-BUTYL N-(3-THIENYL)CARBAMATE
- CAS No.
- 19228-91-2
- Chemical Name:
- TERT-BUTYL N-(3-THIENYL)CARBAMATE
- Synonyms
- N-Boc-3-aminothiophene;TERT-BUTYL 3-THIENYLCARBAMATE;tert-butyl thiophen-3-ylcarbaMate;N-Boc-3-aminothiophene 96%;N-Boc-3-aminothiophene;TERT-BUTYL N-(3-THIENYL)CARBAMATE;3-Aminothiophene, N-BOC protected;Tert-butyl N-thiophen-3-ylcarbamate;3-(tert-Butoxycarbonylamino)thiophene;1,1-Dimethylethyl N-3-thienylcarbamate
- CBNumber:
- CB3760022
- Molecular Formula:
- C9H13NO2S
- Molecular Weight:
- 199.27
- MDL Number:
- MFCD01928808
- MOL File:
- 19228-91-2.mol
- MSDS File:
- SDS
| Melting point | 138 °C |
|---|---|
| Boiling point | 238.1±13.0 °C(Predicted) |
| Density | 1.186±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 13.70±0.70(Predicted) |
| form | wooly crystalline needles |
| color | Off white to faint lemon |
| InChI | 1S/C9H13NO2S/c1-9(2,3)12-8(11)10-7-4-5-13-6-7/h4-6H,1-3H3,(H,10,11) |
| InChIKey | PRWYQCYSADTIBZ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)Nc1ccsc1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
TERT-BUTYL N-(3-THIENYL)CARBAMATE price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 758302 | N-Boc-3-aminothiophene 96% | 19228-91-2 | 1g | $422 | 2026-04-30 | Buy |
| Biosynth | UAA22891 | N-Boc-3-aminothiophene | 19228-91-2 | 0.25g | $250 | 2026-06-05 | Buy |
| Biosynth | UAA22891 | N-Boc-3-aminothiophene | 19228-91-2 | 2.5g | $855.5 | 2026-06-05 | Buy |
| Activate Scientific | AS49330 | tert-Butyl thiophen-3-ylcarbamate 97% | 19228-91-2 | 1g | $20 | 2026-06-04 | Buy |
| Activate Scientific | AS49330 | tert-Butyl thiophen-3-ylcarbamate 97% | 19228-91-2 | 5g | $62 | 2026-06-04 | Buy |
TERT-BUTYL N-(3-THIENYL)CARBAMATE Chemical Properties,Uses,Production
Synthesis
88-13-1
75-65-0
19228-91-2
Preparative Example U-1: Synthesis of tert-butyl N-(3-thienyl)carbamate. 3-Thiophenecarboxylic acid (2.50 g, 19.5 mmol), diphenylphosphoryl azide (4.62 mL, 21.5 mmol), and triethylamine (3.26 mL, 23.4 mmol) were dissolved in tert-butanol (50 mL). The reaction mixture was stirred under reflux conditions for 3.5 hours. Upon completion of the reaction, the reaction solution was cooled to 0 °C and the reaction was quenched by the addition of water. The reaction mixture was subsequently extracted with ethyl acetate and the organic layers were combined and washed with saturated brine. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=10:1) to afford tert-butyl N-(3-thienyl)carbamate (3.33 g, 16.7 mmol, 86% yield) as a white solid.1H-NMR (DMSO-d6) δ (ppm): 1.46 (9H, s), 6.97 (1H, d, J=5.2 Hz ), 7.16 (1H, s), 7.38 (1H, m), 9.61 (1H, s).
References
[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 66
[2] Patent: EP1669348, 2006, A1. Location in patent: Page/Page column 74
[3] Journal of Materials Chemistry C, 2017, vol. 5, # 10, p. 2509 - 2512
[4] Patent: US2006/154875, 2006, A1. Location in patent: Page/Page column 7; 11; 12
[5] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 21, p. 5567 - 5571
TERT-BUTYL N-(3-THIENYL)CARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Synthfine Chemical Co.,Ltd | 15921303235 | sales@synthfine.com | China | 999 | 58 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1576 | 58 | |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4991 | 50 |
View Lastest Price from TERT-BUTYL N-(3-THIENYL)CARBAMATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | tert-Butyl 3-thienylcarbamate
19228-91-2
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2020-01-13 | :TERT-BUTYL N-(3-THIENYL)CARBAMATE
19228-91-2
|
$1.00 | 1KG | 98%-99.9% | 100kg | Career Henan Chemical Co |
-
- tert-Butyl 3-thienylcarbamate
19228-91-2
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- :TERT-BUTYL N-(3-THIENYL)CARBAMATE
19228-91-2
- $1.00
- 98%-99.9%
- Career Henan Chemical Co
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