LY 163443
- CAS No.
- 97581-70-9
- Chemical Name:
- LY 163443
- Synonyms
- LY 163443;2'-Hydroxy-3'-propyl-4'-[4-[(1H-tetrazol-5-yl)methyl]phenoxymethyl]acetophenone;1-[2-Hydroxy-3-propyl-4-[[4-[(1H-tetrazol-5-yl)methyl]phenoxy]methyl]phenyl]ethanone
- CBNumber:
- CB41313549
- Molecular Formula:
- C20H22N4O3
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 97581-70-9.mol
- MSDS File:
- SDS
| FDA UNII | 2KF2DCU28W |
|---|
LY 163443 Chemical Properties, Uses, Production
Uses
LY 163443 is a selective antagonist of leukotrienes D4 (LTD4) and E4 (LTE4). LY 163443 can antagonize LTD4-induced contractions of guinea pig ileum, trachea, and lung parenchyma. LY 163443 also inhibits tracheal contractions to LTE4[1][2].
References
[1] Fleisch JH, et, al. Evaluation of LY163443, 1-[2-hydroxy-3-propyl-4-([4- (1H-tetrazol-5-ylmethyl)phenoxy]methyl) phenyl]ethanone, as a pharmacologic antagonist of leukotrienes D4 and E4. Naunyn Schmiedebergs Arch Pharmacol. 1986 May;333(1):70-7. DOI:10.1007/BF00569663
[2] Bitterman H, et, al. Use of a novel peptide leukotriene receptor antagonist, Ly-163443, in splanchnic artery occlusion shock. Prostaglandins Leukot Essent Fatty Acids. 1988 May;32(2):63-70. DOI:10.1016/0952-3278(88)90097-x
LY 163443 Preparation Products And Raw materials
Raw materials
Preparation Products
LY 163443 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
