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4-Hydroxy-6-aminopyrimidine

4-Hydroxy-6-aminopyrimidine structure

CAS No.: 1193-22-2

Chemical Name:: 4-Hydroxy-6-aminopyrimidine

Synonyms: 6-AMINOPYRIMIDIN-4-OL;6-AMINOPYRIMIDIN-4(3H)-ONE;4-AMINO-6-HYDROXYPYRIMIDINE;NSC 19868;4-AMino-6-pyriMidinol;6-Amino-4-pyrimidinol;6-Amino-3H-pyrimidin-4-one;6-amino-1H-pyrimidin-4-one;6-Amino-4(1H)-pyrimidinone;6-Amino-4(3H)-pyrimidinone

CBNumber:: CB4135450

Molecular Formula:: C4H5N3O

Molecular Weight:: 111.1

MDL Number:: MFCD00051502

MOL File:: 1193-22-2.mol

Last updated:2025-07-24 18:13:41

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4-Hydroxy-6-aminopyrimidine Properties

Melting point	262-264°C
Boiling point	227.5±43.0 °C(Predicted)
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO
form	Solid
pka	10.04±0.40(Predicted)
color	White
BRN	112429
InChI	InChI=1S/C4H5N3O/c5-3-1-4(8)7-2-6-3/h1-2H,(H3,5,6,7,8)
InChIKey	HFMLLTVIMFEQRE-UHFFFAOYSA-N
SMILES	C1=NC(N)=CC(=O)N1
CAS DataBase Reference	1193-22-2(CAS DataBase Reference)
UNSPSC Code	12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

36/37/38-41

Safety Statements

26-36-39

HazardClass

IRRITANT

HS Code

2933599590

NFPA 704

	1
2		0

4-Hydroxy-6-aminopyrimidine price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	A2439	4-Amino-6-hydroxypyrimidine >98.0%(T)	1193-22-2	1g	$32	2025-07-31	Buy
TCI Chemical	A2439	4-Amino-6-hydroxypyrimidine >98.0%(T)	1193-22-2	5g	$137	2025-07-31	Buy
TRC	A611665	4-Amino-6-hydroxypyrimidine	1193-22-2	100mg	$55	2021-12-16	Buy
TRC	A629075	6-Aminopyrimidin-4-ol	1193-22-2	5g	$1100	2021-12-16	Buy
Usbiological	A1380-24	6-Aminopyrimidin-4-ol	1193-22-2	500mg	$425	2021-12-16	Buy

Product number	Packaging	Price	Buy
A2439	1g	$32	Buy
A2439	5g	$137	Buy
A611665	100mg	$55	Buy
A629075	5g	$1100	Buy
A1380-24	500mg	$425	Buy

4-Hydroxy-6-aminopyrimidine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Synthesis

1004-40-6

1193-22-2

Step 2: 2-mercapto-4-amino-6-hydroxypyridine (mass ratio 1:15) was added to 25% ammonia, followed by the addition of activated nickel and titanium dioxide, wherein the molar ratio of 2-mercapto-4-amino-6-hydroxypyridine, activated nickel and titanium dioxide was 1:4:1.5. The mixture was heated to 90°C and the reaction was carried out at reflux for 5 hours. Upon completion of the reaction, the activated nickel and titanium dioxide were removed by thermal filtration. The filtrate was cooled to room temperature and the solid product was precipitated. The solid was washed with 30 mL of water and dried at 40 °C to afford 4-amino-6-hydroxypyrimidine in 98.4% yield.

References

[1] Patent: CN105218554, 2016, A. Location in patent: Paragraph 0023
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 9, p. 1918 - 1929
[3] Patent: EP1406911, 2016, B1. Location in patent: Paragraph 00382; 00383

4-Hydroxy-6-aminopyrimidine Preparation Products And Raw materials

Raw materials

Ethanol 4,6-Dichloropyrimidine RANEY NICKEL Ethyl acetate Hydrochloric acid

HYDRAZINE Diisopropyl ether Ammonia 6-Aminothiouracil TITANIUM DIOXIDE

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Preparation Products

4-Hydroxy-6-aminopyrimidine Suppliers

Global( 196)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1202	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei Jusheng Technology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Unipharm pharmaceutical industry Co., Ltd	58

View Lastest Price from 4-Hydroxy-6-aminopyrimidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-12-10	4-Hydroxy-6-aminopyrimidine 1193-22-2	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2019-07-14	4-Hydroxy-6-aminopyrimidine 1193-22-2	US $1.00 / KG	1KG	90%-99.9%	500kg	Career Henan Chemical Co
2019-07-10	4-Hydroxy-6-aminopyrimidine 1193-22-2	US $1.00 / KG	1KG	90%-99.9%	500kg	Career Henan Chemical Co

4-Hydroxy-6-aminopyrimidine
1193-22-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Hydroxy-6-aminopyrimidine
1193-22-2
US $1.00 / KG
90%-99.9%
Career Henan Chemical Co

4-Hydroxy-6-aminopyrimidine
1193-22-2
US $1.00 / KG
90%-99.9%
Career Henan Chemical Co

4-Hydroxy-6-aminopyrimidine Spectrum

4-Hydroxy-6-aminopyrimidine(1193-22-2)MS 4-Hydroxy-6-aminopyrimidine(1193-22-2)¹HNMR 4-Hydroxy-6-aminopyrimidine(1193-22-2)¹HNMR 4-Hydroxy-6-aminopyrimidine(1193-22-2)IR1 4-Hydroxy-6-aminopyrimidine(1193-22-2)IR2

1193-22-2(4-Hydroxy-6-aminopyrimidine)Related Search:

2,4-Diamino-6-hydroxypyrimidine ,98% 2-Cyanoamino-4,6-dihydroxypyrimidine 6-Aminothiouracil 2,5-Diamino-4,6-dihydroxy-pyrimidine 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE

4,6-Dihydroxy-2-methylpyrimidine 2-Amino-4,6-dimethoxypyrimidine 4,5-DIAMINO-6-HYDROXYPYRIMIDINE SULFATE 2,4,5-Triamino-6-chloropyrimidine hydrochloride 2-Amino-4,6-dihydroxypyrimidine

2-AMINO-4,6-DIHYDROXY-5-NITROPYRIMIDINE 5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE ETRIMFOS 4-Hydroxy-6-aminopyrimidine 4,6-DIHYDROXY-5-NITROPYRIMIDINE

5-Bromo-4,6-dihydroxypyrimidine 2,5-Diamino-4,6-dihydropyrimidine hemisulfate salt 2-Methylthio-4,6-pyrimidinedione

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4(3H)-Pyrimidinone, 6-amino- 4-AMINO-6-HYDROXYPYRIMIDINE 6-AMINOPYRIMIDIN-4(3H)-ONE 6-AMINOPYRIMIDIN-4-OL 6-amino-1H-pyrimidin-4-one 4(1H)-Pyrimidinone, 6-amino- (8CI,9CI) 6-Amino-3H-pyrimidin-4-one 4(1H)-Pyrimidinone, 6-amino- 6-AMINO-4-HYDROXYPYRIMIDINE 6-amino-4(1H)-Pyrimidinone (8CI,9CI) 4-Hydroxy-6-aminopyrimidine 4-Amino-6(1H)-oxopyrimidine 6-Amino-3,4-dihydropyrimidine-4-one 6-Amino-4(1H)-pyrimidinone 6-Amino-4(3H)-pyrimidinone 6-Aminopyrimidine-4(3H)-one 4-AMino-6-pyriMidinol NSC 19868 6-AMino-4-pyriMidinol 4-AMino-6-hydroxypyriMidine 6-azanyl-1H-pyrimidin-4-one 6-Amino-4-pyrimidinol 6-Amino-4(1H)-pyrimidinone 4-Amino-6-hydroxypyrimidine > 6-Amino-4-pyrimidinol 4-Hydroxy-6-aminopyrimidine ISO 9001：2015 REACH 1193-22-2 Bases & Related Reagents Heterocycles Nucleotides Heterocycle-Pyrimidine series Pyridines, Pyrimidines, Purines and Pteredines PYRIMIDINE Fluorobenzene Heterocyclic Compounds Nucleotides and Nucleosides Pyrimidines