ChemicalBook >> CAS DataBase List >>3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]-

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]-

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- structure

CAS No.: 1807873-14-8

Chemical Name:: 3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]-

Synonyms: 3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]-

CBNumber:: CB414686357

Molecular Formula:: C23H26ClF3N2O2

Molecular Weight:: 454.91

MDL Number:

MOL File:: 1807873-14-8.mol

Last updated:2025-04-17 18:22:24

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3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- Properties

Boiling point	559.9±50.0 °C(predicted)
Density	1.311±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	2.70±0.20(predicted)

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Arctom	HY-158417	KSI-6666 96.15%	1807873-14-8	5mg	$347	2026-05-26	Buy
Arctom	HY-158417	KSI-6666 96.15%	1807873-14-8	10mM*1mLinDMSO(Solution)	$347	2026-05-26	Buy
Arctom	HY-158417	KSI-6666 96.15%	1807873-14-8	10mM*1mLinDMSO(Solid+Solvent)	$347	2026-05-26	Buy
Arctom	HY-158417	KSI-6666 96.15%	1807873-14-8	10mg	$559	2026-05-26	Buy
Arctom	HY-158417	KSI-6666 96.15%	1807873-14-8	25mg	$1051	2026-05-26	Buy

Product number	Packaging	Price	Buy
HY-158417	5mg	$347	Buy
HY-158417	10mM*1mLinDMSO(Solution)	$347	Buy
HY-158417	10mM*1mLinDMSO(Solid+Solvent)	$347	Buy
HY-158417	10mg	$559	Buy
HY-158417	25mg	$1051	Buy

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- Chemical Properties, Uses, Production

Uses

KSI-6666 is an orally active, competitive antagonist for sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 of 6.4 nM. KSI-6666 exhibits anti-inflammatory efficacy in autoimmune encephalomyelitis model and T cell transfer colitis model[1].

IC 50

S1PR1: 6.4 nM (IC₅₀)

References

[1] Maruyama Y, et al. Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist[J]. bioRxiv, 2023: 2023.05. 08.539826.

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29873	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

1807873-14-8 (3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]-) Related Search:

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3-Azetidinecarboxylic acid, 1-[[5-[1-[[4-chloro-3-(trifluoromethyl)phenyl]ethylamino]ethyl]-2-methylphenyl]methyl]- 1807873-14-8