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1-(4-Methoxy-1-naphthyl)ethanone

CAS No.
24764-66-7
Chemical Name:
1-(4-Methoxy-1-naphthyl)ethanone
Synonyms
1-Acetyl-4-methoxynaphthalene;1-(4-METHOXY-1-PHTHYL)ETHANONE;1-(4-Methoxy-1-naphthyl)ethanone;4-Methoxy-1-Naphthyl Ethyl Ketone;1-(4-methoxynaphthalen-1-yl)ethanone;1-(4-Methoxy-1-naphthalenyl)-ethanone;Ethanone, 1-(4-methoxy-1-naphthalenyl)-
CBNumber:
CB41490152
Molecular Formula:
C13H12O2
Molecular Weight:
200.23
MDL Number:
MFCD00156696
MOL File:
24764-66-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:22

1-(4-Methoxy-1-naphthyl)ethanone Properties

storage temp. Sealed in dry,Room Temperature
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1-(4-Methoxy-1-naphthyl)ethanone price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS93009 1-Acetyl-4-methoxynaphthalene 97% 24764-66-7 5g $21 2026-06-04 Buy
Activate Scientific AS93009 1-Acetyl-4-methoxynaphthalene 97% 24764-66-7 25g $37 2026-06-04 Buy
Activate Scientific AS93009 1-Acetyl-4-methoxynaphthalene 97% 24764-66-7 100g $112 2026-06-04 Buy
Matrix Scientific 157090 1-(4-Methoxy-1-naphthyl)ethanone 24764-66-7 1.00g $200 2026-05-18 Buy
Matrix Scientific 157090 1-(4-Methoxy-1-naphthyl)ethanone 24764-66-7 5.00g $700 2026-05-18 Buy
Product number Packaging Price Buy
AS93009 5g $21 Buy
AS93009 25g $37 Buy
AS93009 100g $112 Buy
157090 1.00g $200 Buy
157090 5.00g $700 Buy

1-(4-Methoxy-1-naphthyl)ethanone Chemical Properties,Uses,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 540, 1971 DOI: 10.1021/jo00803a011
Tetrahedron Letters, 31, p. 3933, 1990 DOI: 10.1016/S0040-4039(00)97510-5

Synthesis

Acetyl chloride

75-36-5

1-Methoxynaphthalene

2216-69-5

1-(4-METHOXY-1-NAPHTHYL)ETHANONE

24764-66-7

Aluminum trichloride (800 mg, 6 mmol) in anhydrous dichloromethane (12 mL) was cooled to 0 °C under nitrogen protection and acetyl chloride (236 mg, 3 mmol) was slowly added. The reaction mixture was stirred at room temperature for 10 min before 1-methoxynaphthalene (474 mg, 3 mmol) was added and stirring was continued at room temperature overnight. After completion of the reaction, the reaction was quenched with water, the organic phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether=1:15, v/v) to afford 4-methoxynaphthaleneacetophenone (338 mg, 56% yield) as a white solid.1H NMR (300 MHz, CDCl3) δ: 9.01-9.96 (m, 1H), 8.32-8.35 (m, 1H), 8.03 (d, 1H), 7.63-7.65 (m, 1H), 7.53-7.58 (m, 1H), 6.79 (d, 1H), 4.07 (s, 3H), 2.72 (s, 3H).LC-MS: m/z 201 [M+1]+.

References

[1] Canadian Journal of Chemistry, 1981, vol. 59, p. 2629 - 2641
[2] Patent: US2012/220629, 2012, A1. Location in patent: Page/Page column 46
[3] Patent: WO2012/113103, 2012, A1. Location in patent: Page/Page column 62-63
[4] Recueil des Travaux Chimiques des Pays-Bas, 1945, vol. 64, p. 214,216
[5] Zhurnal Obshchei Khimii, 1938, vol. 8, p. 402,407

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View Lastest Price from 1-(4-Methoxy-1-naphthyl)ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(4-METHOXY-1-NAPHTHYL)ETHANONE pictures 2026-08-13 1-(4-METHOXY-1-NAPHTHYL)ETHANONE
24764-66-7
1KG 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
1-(4-METHOXY-1-NAPHTHYL)ETHANONE pictures 2024-10-22 1-(4-METHOXY-1-NAPHTHYL)ETHANONE
24764-66-7
$1.30 1g 98% 10kg Career Henan Chemica Co

1-(4-Methoxy-1-naphthyl)ethanone Spectrum

Ethanone, 1-(4-methoxy-1-naphthalenyl)- 1-(4-Methoxy-1-naphthalenyl)-ethanone 1-(4-Methoxy-1-naphthyl)ethanone 1-(4-methoxynaphthalen-1-yl)ethanone 1-Acetyl-4-methoxynaphthalene 1-(4-METHOXY-1-PHTHYL)ETHANONE 4-Methoxy-1-Naphthyl Ethyl Ketone 24764-66-7 PAHs series