S-TRITYL-3-MERCAPTOPROPIONIC ACID
- CAS No.
- 27144-18-9
- Chemical Name:
- S-TRITYL-3-MERCAPTOPROPIONIC ACID
- Synonyms
- Mpa(Trt);Mpa(Trt)-OH;Mpr(trt);MPR(TRT)-OH;3-(Tritylthio)propanoic acid;3-(Tritylthio)propionic acid;3-MPA(Trt);3-TRITYLMERCAPTO PROPIONIC ACID;Nsc96707;Trt-Mpa-OH
- CBNumber:
- CB4192048
- Molecular Formula:
- C22H20O2S
- Molecular Weight:
- 348.46
- MDL Number:
- MFCD00237291
- MOL File:
- 27144-18-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-(Tritylthio)propionic acid ≥97.0% (T) | 53695 | 1g | $136 |
| 3-(Tritylthio)propionic acid ≥97.0% (T) | 53695 | 1g-f | $117 |
| 3-(Tritylthio)propanoic Acid | T2179 | 5G | $30 |
| 3-(Tritylthio)propanoic Acid | T2179 | 25G | $90 |
| 3-TritylsulfanylpropionicAcid | T889475 | 5g | $60 |
| More product size | |||
| Melting point | 211-213°C |
|---|---|
| Boiling point | 503.8±38.0 °C(Predicted) |
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly, Heated), DMSO (Soluble), Methanol (Slightly) |
| pka | 4.59±0.10(Predicted) |
| form | Solid |
| color | Off-White |
| Water Solubility | Partly miscible in water. |
| Sensitive | Air Sensitive |
| InChI | InChI=1S/C22H20O2S/c23-21(24)16-17-25-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2,(H,23,24) |
| InChIKey | AECGEIVNZGQBJT-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| CAS DataBase Reference | 27144-18-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335-H413 | |||||||||
| Precautionary statements | P273-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 4 Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
S-TRITYL-3-MERCAPTOPROPIONIC ACID price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53695 | 3-(Tritylthio)propionic acid ≥97.0% (T) | 27144-18-9 | 1g | $136 | 2025-07-31 | Buy |
| Sigma-Aldrich | 53695 | 3-(Tritylthio)propionic acid ≥97.0% (T) | 27144-18-9 | 1g-f | $117 | 2021-12-16 | Buy |
| TCI Chemical | T2179 | 3-(Tritylthio)propanoic Acid | 27144-18-9 | 5G | $30 | 2025-07-31 | Buy |
| TCI Chemical | T2179 | 3-(Tritylthio)propanoic Acid | 27144-18-9 | 25G | $90 | 2025-07-31 | Buy |
| TRC | T889475 | 3-TritylsulfanylpropionicAcid | 27144-18-9 | 5g | $60 | 2021-12-16 | Buy |
S-TRITYL-3-MERCAPTOPROPIONIC ACID Chemical Properties,Uses,Production
Chemical Properties
White to off-white powder
Uses
Preparation and structural modification of 3-Tritylsulfanylpropionic Acid possesses antileukemic activity against leukemia.
Synthesis
76-84-6
107-96-0
27144-18-9
General procedure for the synthesis of 3-(triphenylmethylthio)propionic acid from triphenylmethanol and 3-mercaptopropionic acid: 1. 100 g of 3-mercaptopropionic acid (942.15 mmol) was dissolved in 300 mL of glacial acetic acid at room temperature. 2. 245.27 g of triphenylmethanol (942.15 mmol) was dissolved in 736.79 mL of tetrahydrofuran (THF) at room temperature. 3. Slowly add the solution obtained from step 1 to the solution from step 2. 4. 16.62 g of concentrated sulfuric acid (98%, 169.587 mmol) is added slowly and dropwise at 28° C to 30° C. The reaction mixture is insulated. 5. The reaction mixture was stirred under insulating conditions for 4 hours. 6. Upon completion of the reaction, 360 g of solid crude product was obtained by filtration. 7. The crude product was dissolved in 720 mL of N,N-dimethylformamide (DMF). 8. 5 times the volume of water was added to the solution, filtered and dried to give 295.5 g of refined product in 90% yield. 9. The structure of the product was confirmed by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR).
References
[1] Organic Letters, 2017, vol. 19, # 12, p. 3195 - 3198
[2] Patent: CN106380430, 2017, A. Location in patent: Paragraph 0017; 0018; 0019; 0020
[3] Chemical Communications, 2014, vol. 50, # 35, p. 4571 - 4574
[4] Australian Journal of Chemistry, 1990, vol. 43, # 3, p. 629 - 634
[5] Journal of Medicinal Chemistry, 2000, vol. 43, # 8, p. 1448 - 1455
S-TRITYL-3-MERCAPTOPROPIONIC ACID Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8746 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from S-TRITYL-3-MERCAPTOPROPIONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-06 | S-TRITYL-3-MERCAPTOPROPIONIC ACID
27144-18-9
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-10-13 | 3-(Tritylthio)propionic acid
27144-18-9
|
US $3.00-9.00 / KG | 0.1KG | 99% | g-kg-tons, free sample is available | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2024-04-24 | 3-(Tritylthio)propionic acid
27144-18-9
|
US $100.00-30.00 / kg | 1kg | 99.93% | 1000kg per week | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- S-TRITYL-3-MERCAPTOPROPIONIC ACID
27144-18-9
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-(Tritylthio)propionic acid
27144-18-9
- US $3.00-9.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 3-(Tritylthio)propionic acid
27144-18-9
- US $100.00-30.00 / kg
- 99.93%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
