Coumarin 106
- CAS No.
- 41175-45-5
- Chemical Name:
- Coumarin 106
- Synonyms
- COUMARIN 478;COUMARIN 106;11-hexahydro-;Exciton Coumarin 478;Coumarin106,lasergrade;Coumarin 106Coumarin 478;Coumarin 106,pure,laser grade;COUMARIN 106, LASER GRADE, PURE;1h,5h-cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9h)-one,2,3,6,7,10,;2,3,5,6,7,9,10,11-octahydrocyclopenta[4,5]pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-12(1H)-one
- CBNumber:
- CB6178790
- Molecular Formula:
- C18H19NO2
- Molecular Weight:
- 281.35
- MDL Number:
- MFCD00041949
- MOL File:
- 41175-45-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149 °C |
|---|---|
| Boiling point | 538.4±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| solubility | DMSO: Slightly soluble: 0.1-1 mg/ml |
| pka | 6.38±0.20(Predicted) |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| λmax | 375nm(Acetone)(lit.) |
| FDA UNII | 9RGV583D48 |
| EPA Substance Registry System | 1H,5H-Cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9H)-one, 2,3,6,7,10,11-hexahydro- (41175-45-5) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xn |
|---|---|
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 37/39-26 |
| TSCA | TSCA listed |
| HS Code | 29322985 |
Coumarin 106 price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C3043 | Coumarin 478 >98.0%(HPLC) | 41175-45-5 | 200mg | $156 | 2026-04-30 | Buy |
| Cayman Chemical | 40754 | Coumarin 478 ≥98% | 41175-45-5 | 50mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 40754 | Coumarin 478 ≥98% | 41175-45-5 | 100mg | $137 | 2026-04-30 | Buy |
| Cayman Chemical | 40754 | Coumarin 478 ≥98% | 41175-45-5 | 250mg | $323 | 2026-04-30 | Buy |
| ChemScene | CS-0364909 | Coumarin 106 ≥98% | 41175-45-5 | 100mg | $100 | 2026-06-04 | Buy |
Coumarin 106 Chemical Properties,Uses,Production
Description
Coumarin 478 is a vital chemical compound used in biomedicine mainly for its anticancer properties. It has demonstrated potential in inhibiting tumor growth and metastasis, making it a valuable drug in the treatment of various types of cancers. Coumarin 478 shows promising results in clinical trials and is actively being researched for its effectiveness against specific cancer types.
Chemical Properties
yellow powder and chunks
Uses
Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC50=4.97 and Ki=2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency (pIC50=4.56)[1][2].
References
[1] Patil SK, et al. Determination of ground and excited state dipole moments of dipolar laser dyes by solvatochromic shift method. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:117-26. DOI:10.1016/j.saa.2013.12.031
[2] Fallarero A, et al. Inhibition of acetylcholinesterase by coumarins: the case of coumarin 106. Pharmacol Res. 2008 Sep-Oct;58(3-4):215-21. DOI:10.1016/j.phrs.2008.08.001
[3] G.A. REYNOLDS K. H D. New coumarin dyes with rigidized structure for flashlamp-pumped dye lasers[J]. Optics Communications, 1975, 13 3: Pages 222-225. DOI: 10.1016/0030-4018(75)90085-1
[4] EMMA ALEXANDER. Room temperature phosphorescence of coumarin 106 with direct triplet state excitation[J]. Dyes and Pigments, 2023, 217: Article 111389. DOI: 10.1016/j.dyepig.2023.111389
Coumarin 106 Preparation Products And Raw materials
Raw materials
Preparation Products
Coumarin 106 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| WuHan Taiyukaishang Chemical Co., Ltd. | 027-027-87680032 18963957250 | taiyuchem@163.com | China | 180 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
| TCI AMERICA | 800-4238616 | sales@tciamerica.com | Americas | 23636 | 75 |
| Shanghai Xingui Biotechnology Co., Ltd. | 15121041756 | xingui2022@126.com | China | 9985 | 58 |
| Tianjin Being Technology Co., Ltd. | 18622939839 | tjby921@163.com | China | 614 | 55 |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 7580 | 55 |
View Lastest Price from Coumarin 106 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | Coumarin 106
41175-45-5
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Coumarin 106
41175-45-5
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
