2-Chloro-3-fluoronitrobenzene
- CAS No.
- 21397-07-9
- Chemical Name:
- 2-Chloro-3-fluoronitrobenzene
- Synonyms
- 2-CHLORO-3-FLUORONITROBENZENE;1-Nitro-2-chloro-3-fluorobenzene;2-CHLORO-1-FLUORO-3-NITRO-BENZENE;1-CHLORO-2-FLUORO-6-NITRO-BENZENE;Benzene, 2-chloro-1-fluoro-3-nitro-;2-Chloro-3-fluoronitrobenzene CAS NO.21397-07-9;2-Chloro-3-fluoronitrobenzene ISO 9001：2015 REACH
- CBNumber:
- CB4293246
- Molecular Formula:
- C6H3ClFNO2
- Molecular Weight:
- 175.54
- MDL Number:
- MFCD04112549
- MOL File:
- 21397-07-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-3-fluoronitrobenzene 98% | C41932 | 1g | $51 |
| 2-Chloro-3-fluoronitrobenzene 98% | C41932 | 5g | $60 |
| 2-Chloro-3-fluoronitrobenzene 98% | C41932 | 10g | $80 |
| 2-Chloro-3-fluoronitrobenzene 98% | C41932 | 25g | $160 |
| 2-Chloro-3-fluoronitrobenzene 98% | CD12096243 | 25g | $152 |
| More product size | |||
| Boiling point | 237-239 °C |
|---|---|
| Density | 1.494±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | low melting solid |
| color | Brown |
| CAS DataBase Reference | 21397-07-9(CAS DataBase Reference) |
| FDA UNII | 79J6SA7GHB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | T |
| HS Code | 2904990090 |
2-Chloro-3-fluoronitrobenzene price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | C41932 | 2-Chloro-3-fluoronitrobenzene 98% | 21397-07-9 | 1g | $51 | 2026-05-06 | Buy |
| Synthonix | C41932 | 2-Chloro-3-fluoronitrobenzene 98% | 21397-07-9 | 5g | $60 | 2026-05-06 | Buy |
| Synthonix | C41932 | 2-Chloro-3-fluoronitrobenzene 98% | 21397-07-9 | 10g | $80 | 2026-05-06 | Buy |
| Synthonix | C41932 | 2-Chloro-3-fluoronitrobenzene 98% | 21397-07-9 | 25g | $160 | 2026-05-06 | Buy |
| Crysdot | CD12096243 | 2-Chloro-3-fluoronitrobenzene 98% | 21397-07-9 | 25g | $152 | 2026-05-20 | Buy |
2-Chloro-3-fluoronitrobenzene Chemical Properties,Uses,Production
Uses
2-Chloro-3-fluoronitrobenzene can be used in substitution reactions to prepare other organic heterocyclic compounds. Its derivatives are also used as raw materials for the synthesis of aromatic polyimides.
Synthesis
402-67-5
21397-07-9
General procedure for the synthesis of 2-chloro-3-fluoronitrobenzene from 3-fluoronitrobenzene: To a solution of 3-fluoronitrobenzene (2 g, 14.2 mmol) in tetrahydrofuran (THF, 30 mL) was slowly added a solution of N-chlorosuccinimide (5.69 g, 42.6 mmol) in THF (20 mL) at -78 °C. Subsequently, NaHMDS (28.4 mL, 28.4 mmol) in a 1 M solution of THF was added dropwise while ensuring that the internal temperature of the reaction system was maintained below -75 °C. The reaction mixture was stirred continuously at -78 °C for 30 min. Upon completion of the reaction, the mixture was partitioned between 5% hydrochloric acid and ethyl acetate. The organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and the solvent evaporated. The resulting solid was purified by silica gel column chromatography with the eluent being a hexane solution of 20% ethyl acetate, resulting in the target product 2-chloro-3-fluoronitrobenzene (231 mg, 9.2% yield). The structure of the product was confirmed by EI-MS, m/z 176.5 (M+).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 15, p. 3365 - 3369
[2] Journal of Organic Chemistry, 2011, vol. 76, # 9, p. 3416 - 3437
[3] Patent: US6500863, 2002, B1
2-Chloro-3-fluoronitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29816 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from 2-Chloro-3-fluoronitrobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-27 | 2-Chloro-3-fluoronitrobenzene
21397-07-9
|
US $0.00 / KG | 1KG | 97.1% | 100 tons | Honest Joy Holdings Limited | |
 |
2019-07-14 | 2-Chloro-3-fluoronitrobenzene
21397-07-9
|
US $1.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 2-Chloro-3-fluoronitrobenzene
21397-07-9
- US $0.00 / KG
- 97.1%
- Honest Joy Holdings Limited
-
- 2-Chloro-3-fluoronitrobenzene
21397-07-9
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
