4-Amino-2-methylbenzoic acid
- CAS No.
- 2486-75-1
- Chemical Name:
- 4-Amino-2-methylbenzoic acid
- Synonyms
- 4-Amino-o-toluic;Tolvaptan Impurity 33;4-Amino-2-methylbenzoicaci;4-Amino-2-methybenzoic acid;4-AMINO-2-METHYLBENZOIC ACID;2-METHYL-4-AMINO-BENZOIC ACID;4-amino-2-methylbenozoic acid;4-azanyl-2-methyl-benzoic acid;Benzoic acid, 4-amino-2-methyl-;4-Amino-2-methylbenzoic Acid >
- CBNumber:
- CB4321053
- Molecular Formula:
- C8H9NO2
- Molecular Weight:
- 151.16
- MDL Number:
- MFCD06656133
- MOL File:
- 2486-75-1.mol
| Product description | Number | Pack Size | Price |
| 4-Amino-2-methylbenzoic acid 95% | 691437 | 5g | $85.5 |
| 4-Amino-2-methylbenzoic Acid >98.0%(HPLC)(T) | A2349 | 5g | $30 |
| 4-Amino-2-methylbenzoic Acid >98.0%(HPLC)(T) | A2349 | 25g | $120 |
| 4-Amino-2-methylbenzoic Acid | A637858 | 50mg | $45 |
| 4-Amino-2-methylbenzoic Acid | A637858 | 100mg | $60 |
| More product size | |||
| Melting point | 160-165 °C |
|---|---|
| Boiling point | 339.5±30.0 °C(Predicted) |
| Density | 1.254±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Methanol |
| form | Solid |
| pka | 4.86±0.25(Predicted) |
| color | Light orange to Yellow to Green |
| InChI | InChI=1S/C8H9NO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4H,9H2,1H3,(H,10,11) |
| InChIKey | XRSQZFJLEPBPOZ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(N)C=C1C |
| CAS DataBase Reference | 2486-75-1(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
4-Amino-2-methylbenzoic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 691437 | 4-Amino-2-methylbenzoic acid 95% | 2486-75-1 | 5g | $85.5 | 2025-07-31 | Buy |
| TCI Chemical | A2349 | 4-Amino-2-methylbenzoic Acid >98.0%(HPLC)(T) | 2486-75-1 | 5g | $30 | 2025-07-31 | Buy |
| TCI Chemical | A2349 | 4-Amino-2-methylbenzoic Acid >98.0%(HPLC)(T) | 2486-75-1 | 25g | $120 | 2025-07-31 | Buy |
| TRC | A637858 | 4-Amino-2-methylbenzoic Acid | 2486-75-1 | 50mg | $45 | 2021-12-16 | Buy |
| TRC | A637858 | 4-Amino-2-methylbenzoic Acid | 2486-75-1 | 100mg | $60 | 2021-12-16 | Buy |
4-Amino-2-methylbenzoic acid Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
1975-51-5
2486-75-1
GENERAL STEPS: Prior to each experiment, the tubular reaction apparatus was equilibrated by pumping solvent for 30 min at 16 bar hydrogen pressure (see Fig. 4). An Omnifit reaction cartridge (20.0 mm outer diameter, 15.0 mm inner diameter) containing 1 g Pd/C catalyst was used. To prevent overpressurization of the system in case of blockage, the upper pressure of the Knauer pump was set to 25 bar. with the injection ring disconnected from the flow line, the injection ring was opened and manually injected with 3.6 mL of a 0.076 M ethanol solution of 2-methyl-4-nitrobenzoic acid (excess feedstock solution in the ring was recovered for reuse). The injection ring was then closed and plugged into the flow stream. Collect the product at the outlet of the system downstream of the backpressure regulator for 120 min. The solvent is removed by reduced pressure distillation (first using a rotary evaporator and then a secondary rotary vane pump) to give 4-amino-2-methylbenzoic acid.
References
[1] Tetrahedron, 2018, vol. 74, # 47, p. 6795 - 6803
[2] Chemische Berichte, 1884, vol. 17, p. 161
[3] Patent: US2012/46467, 2012, A1. Location in patent: Page/Page column 26
4-Amino-2-methylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12245 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2954 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from 4-Amino-2-methylbenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | Tolvaptan Impurity 6
2486-75-1
|
US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2025-09-25 | Tolvaptan Impurity 33 | US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
 |
2025-08-08 | 4-Amino-2-methylbenzoic acid
2486-75-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Sichuan Zhuoyu Yantang Technology Co., Ltd. |
-
- Tolvaptan Impurity 6
2486-75-1
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Tolvaptan Impurity 33
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- 4-Amino-2-methylbenzoic acid
2486-75-1
- US $0.00 / KG
- 99%
- Sichuan Zhuoyu Yantang Technology Co., Ltd.
