2-Amino-6-bromopyridine
- CAS No.
- 19798-81-3
- Chemical Name:
- 2-Amino-6-bromopyridine
- Synonyms
- 6-Bromopyridin-2-amine;2-AMINO-6-BROMO-PHENOL; 19798-81-3;Aminobromopyridine;2-AMINO-6-BROMPYRIDINE;2A6BP;6-BROMO-2-PYRIDINAMINE;2-Bromo-6-Aminopyridine;6-BROMO-2-AMINOPYRIDINE;2-PyridinaMine,6-broMo-
- CBNumber:
- CB4471572
- Molecular Formula:
- C5H5BrN2
- Molecular Weight:
- 173.01
- MDL Number:
- MFCD00137843
- MOL File:
- 19798-81-3.mol
- MSDS File:
- SDS
| Melting point | 88-91 °C (lit.) |
|---|---|
| Boiling point | 273.0±20.0 °C(Predicted) |
| Density | 1.710±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Very Slightly) |
| pka | 2.73±0.24(Predicted) |
| form | Powder |
| color | Slightly yellow to light brown |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C5H5BrN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8) |
| InChIKey | BKLJUYPLUWUEOQ-UHFFFAOYSA-N |
| SMILES | C1(N)=NC(Br)=CC=C1 |
| CAS DataBase Reference | 19798-81-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333999 | |||||||||
| NFPA 704 |
|
2-Amino-6-bromopyridine price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 521744 | 2-Amino-6-bromopyridine 98% | 19798-81-3 | 5g | $45.9 | 2025-07-31 | Buy |
| Sigma-Aldrich | 521744 | 2-Amino-6-bromopyridine 98% | 19798-81-3 | 25g | $107 | 2025-07-31 | Buy |
| TCI Chemical | A1529 | 2-Amino-6-bromopyridine >98.0%(T) | 19798-81-3 | 5g | $59 | 2025-07-31 | Buy |
| TCI Chemical | A1529 | 2-Amino-6-bromopyridine >98.0%(T) | 19798-81-3 | 25g | $166 | 2025-07-31 | Buy |
| TRC | A601945 | 2-Amino-6-bromopyridine | 19798-81-3 | 10g | $150 | 2021-12-16 | Buy |
2-Amino-6-bromopyridine Chemical Properties,Uses,Production
Chemical Properties
Slightly yellow to light brown powder
Uses
2-Amino-6-bromopyridine is a disubstituted pyridine used as a building block in the preparation of nitrogen containing bicyclic and polycylic compounds.
Uses
Employed in an efficient one-pot synthesis of 7-azaindoles. Used in the synthesis of anti-HIV agents.
Application
2-Amino-6-bromopyridine is an important raw material for the synthesis of:
2-amino-6-diethylaminopyridine
2,6-di-(methylamino)-pyridine
3-(6-bromopyridin-2-yl)-2-(2,6-difluorophenyl)-1,3-thiazolidin-4-one
N-(6-bromopyridin-2-yl)dodecylamide
2-bromo-6-iodopyridine
Employed in an efficient one-pot synthesis of 7-azaindoles.
Used in the synthesis of anti-HIV agents.
General Description
2-Amino- 6-bromopyridine has been synthesized from epichlorohydrin.
Synthesis
626-05-1
141-86-6
19798-81-3
14.1 Preparation of 6-bromo-2-aminopyridine In a steel autoclave equipped with a glass liner, 10.00 g of 2,6-dibromopyridine (42.2 mmol) was suspended in 50 mL of concentrated ammonia. The autoclave was sealed and heated to 190°C using a heating jacket and maintained for 6 hours (pressure was raised to about 25 bar). After the autoclave was cooled and depressurized, the reaction mixture was mixed with 100 mL of ethyl acetate for phase separation. The aqueous phase was extracted twice with ethyl acetate, 100 mL each. the organic phases were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was dissolved in 250 mL of a solvent mixture of cyclohexane/ethyl acetate (1:1, v/v) to remove the by-product 2,6-diaminopyridine. Subsequently, the solution was filtered through a short silica gel column (5 x 20 cm) and washed again with 250 mL of cyclohexane/ethyl acetate (1:1, v/v) mixed solvent. After removal of the solvent under reduced pressure, the residue was sublimated at 90°C and 10-1 mbar to give 6.49 g (37.5 mmol, 88.9% yield) of 6-bromo-2-aminopyridine as a white solid.
References
[1] Patent: US2004/199024, 2004, A1. Location in patent: Page 17
[2] Recueil des Travaux Chimiques des Pays-Bas, 1932, vol. 51, p. 381,386, 949
[3] Chemical Communications, 2010, vol. 46, # 6, p. 925 - 927
2-Amino-6-bromopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Yushan Wanfang Biotechnology Co., Ltd. | +86-025-84918180 +86-18014482516 | 3552541679@qq.com | China | 997 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20191 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12932 | 58 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
View Lastest Price from 2-Amino-6-bromopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-04 | 2-Amino-6-bromopyridine
19798-81-3
|
US $29.00 / g | 99.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-07-25 | 2-Amino-6-bromopyridine
19798-81-3
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-05-23 | L-tBuO-Pal-Glu(OSu)-OtBu
19798-81-3
|
US $50.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- 2-Amino-6-bromopyridine
19798-81-3
- US $29.00 / g
- 99.87%
- TargetMol Chemicals Inc.
-
- 2-Amino-6-bromopyridine
19798-81-3
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- L-tBuO-Pal-Glu(OSu)-OtBu
19798-81-3
- US $50.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co Ltd
