ChemicalBook >> CAS DataBase List >>BO-264
BO-264
- CAS No.
- 2408648-20-2
- Chemical Name:
- BO-264
- Synonyms
- BO-264;BO-264, 10 mM in DMSO;3-(4-Methoxyphenyl)-N-(2-morpholinopyrimidin-4-yl)isoxazol-5-amine;3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine;4-Pyrimidinamine, N-[3-(4-methoxyphenyl)-5-isoxazolyl]-2-(4-morpholinyl)-;inhibit,cytotoxicity,antitumor,Fibroblast growth factor receptor,BO-264,Apoptosis,Inhibitor,TACC3,spindle,abnormalities,FGFR,ERK1/2,BO 264,DNA,phosphorylation,FGFR3-TACC3,mitotic,damage,anti-proliferative,BO264
- CBNumber:
- CB46199294
- Molecular Formula:
- C18H19N5O3
- Molecular Weight:
- 353.38
- MDL Number:
- MOL File:
- 2408648-20-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Boiling point | 627.9±65.0 °C(Predicted) |
|---|---|
| Density | 1.306±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (>25 mg/ml) |
| pka | 6.69±0.10(Predicted) |
| form | solid |
| color | Off-white |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
BO-264 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36611 | BO-264 ≥98% | 2408648-20-2 | 5mg | $74 | 2026-04-30 | Buy |
| Cayman Chemical | 36611 | BO-264 ≥98% | 2408648-20-2 | 10mg | $140 | 2026-04-30 | Buy |
| Cayman Chemical | 36611 | BO-264 ≥98% | 2408648-20-2 | 25mg | $293 | 2026-04-30 | Buy |
| Cayman Chemical | 36611 | BO-264 ≥98% | 2408648-20-2 | 50mg | $548 | 2026-04-30 | Buy |
| Biosynth | IWD64820 | 3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine | 2408648-20-2 | 50mg | $993.5 | 2026-06-04 | Buy |
BO-264 Chemical Properties, Uses, Production
Description
BO-264 (2408648-20-2) is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
References
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BO-264 Preparation Products And Raw materials
Raw materials
Preparation Products
BO-264 Suppliers
Global Suppliers ( 75)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4858 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 989 | 55 |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2961 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1940 | 55 |
2408648-20-2 (BO-264) Related Search:
BO-264
4-Pyrimidinamine, N-[3-(4-methoxyphenyl)-5-isoxazolyl]-2-(4-morpholinyl)-
3-(4-Methoxyphenyl)-N-(2-morpholinopyrimidin-4-yl)isoxazol-5-amine
inhibit,cytotoxicity,antitumor,Fibroblast growth factor receptor,BO-264,Apoptosis,Inhibitor,TACC3,spindle,abnormalities,FGFR,ERK1/2,BO 264,DNA,phosphorylation,FGFR3-TACC3,mitotic,damage,anti-proliferative,BO264
BO-264, 10 mM in DMSO
3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine
2408648-20-2
