ChemicalBook >> CAS DataBase List >>4-Hydroxy-3-methoxybenzonitrile
4-Hydroxy-3-methoxybenzonitrile
- CAS No.
- 4421-08-3
- Chemical Name:
- 4-Hydroxy-3-methoxybenzonitrile
- Synonyms
- AKOS B004154;VANILO NITRILE;VANILLONITRILE;4-Hydroxy-3-methoxyb;4-Cyano-2-methoxyphenol;2-methyl-3-phenyl-3-pentanol;3-Methoxy-4-Hydroxybenzonitrle;4-Hydroxy-3-Methoxybenzonitile;3-Methoxy-4-Hydroxybenzonitril;4-Hydroxy-3-methoxybenzonitriL
- CBNumber:
- CB5114702
- Molecular Formula:
- C8H7NO2
- Molecular Weight:
- 149.15
- MDL Number:
- MFCD00001820
- MOL File:
- 4421-08-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 02:25:12
| Melting point | 85-87 °C (lit.) |
|---|---|
| Boiling point | 270.21°C (rough estimate) |
| Density | 1.2517 (rough estimate) |
| refractive index | 1.5320 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 7.84±0.18(Predicted) |
| form | powder to crystal |
| color | White to Light yellow to Light orange |
| InChI | 1S/C8H7NO2/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,10H,1H3 |
| InChIKey | QJRWLNLUIAJTAD-UHFFFAOYSA-N |
| SMILES | COc1cc(ccc1O)C#N |
| LogP | 1.551 (est) |
| CAS DataBase Reference | 4421-08-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-37/39-36/37/39 | |||||||||
| RIDADR | 3439 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Hydroxy-3-methoxybenzonitrile price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 162604 | 4-Hydroxy-3-methoxybenzonitrile 98% | 4421-08-3 | 25G | $96.5 | 2026-04-30 | Buy |
| TCI Chemical | H0620 | 4-Hydroxy-3-methoxybenzonitrile >98.0%(GC)(T) | 4421-08-3 | 5g | $48 | 2026-04-30 | Buy |
| TCI Chemical | H0620 | 4-Hydroxy-3-methoxybenzonitrile >98.0%(GC)(T) | 4421-08-3 | 25g | $187 | 2026-04-30 | Buy |
| Usbiological | 279694 | 4-Hydroxy-3-methoxybenzonitrile Asreported | 4421-08-3 | 50g | $352 | 2026-06-03 | Buy |
| Usbiological | 279694 | 4-Hydroxy-3-methoxybenzonitrile Asreported | 4421-08-3 | 100g | $468 | 2026-06-03 | Buy |
4-Hydroxy-3-methoxybenzonitrile Chemical Properties, Uses, Production
Chemical Properties
beige crystalline powder
Uses
4-Hydroxy-3-methoxybenzonitrile was used in the synthesis of 1,5-bis(4-cyano-2-methoxyphenoxy)-3-oxapentane.
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 2293, 1948 DOI: 10.1021/ja01186a514
General Description
4-Hydroxy-3-methoxybenzonitrile on treatment with sodium perborate yields 4-hydroxy-3-methoxybenzamide.
4-Hydroxy-3-methoxybenzonitrile Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Global Suppliers ( 180)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd | 027-83855310 13476018176 | 408614617@qq.com | China | 998 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
View Latest Price from 4-Hydroxy-3-methoxybenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-09-17 | 4-Hydroxy-3-methoxybenzonitrile
4421-08-3
|
$75.00-100.00 | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
![]() |
2019-07-06 | 4-Hydroxy-3-methoxybenzonitrile
4421-08-3
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-

- 4-Hydroxy-3-methoxybenzonitrile
4421-08-3
- $75.00-100.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-

- 4-Hydroxy-3-methoxybenzonitrile
4421-08-3
- $1.00
- 98%
- Career Henan Chemical Co
4421-08-3 (4-Hydroxy-3-methoxybenzonitrile) Related Search:
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AKOS B004154
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4-Hydroxy-3-methoxybenzonitrile>
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C8 to C9
Building Blocks
Nitrogen Compounds
Organic Building Blocks
Cyanides/Nitriles
Building Blocks
C8 to C9
Chemical Synthesis
Nitrogen Compounds
Organic Building Blocks
Anisoles, Alkyloxy Compounds & Phenylacetates
Nitriles
Phenols
C8 to C9
Cyanides/Nitriles
Nitrogen Compounds
Aromatic Nitriles







