3-Hydroxy-4-methoxybenzonitrile
- CAS No.
- 52805-46-6
- Chemical Name:
- 3-Hydroxy-4-methoxybenzonitrile
- Synonyms
- Benzonitrile, 3-hydroxy-4-Methoxy-;ISOVANILLONITRILE;CBI-BB ZERO/005397;2-methoxy-5-cyanophenol;5-Cyano-2-methoxyphenol;3-Hydroxy-4-methoxybenzonitril;3-HYDROXY-4-METHOXYBENZONITRILE;3-Hydroxy-4-methoxy benzonitrile 95+%;3-Hydroxy-4-methoxybenzonitrile ISO 9001:2015 REACH;3-HYDROXY-4-METHOXYBENZONITRILE (ISOVANILLONITRILE)
- CBNumber:
- CB6287199
- Molecular Formula:
- C8H7NO2
- Molecular Weight:
- 149.15
- MDL Number:
- MFCD02258854
- MOL File:
- 52805-46-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 124 °C |
|---|---|
| Boiling point | 300.8±27.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 8.59±0.10(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 52805-46-6(CAS DataBase Reference) |
3-Hydroxy-4-methoxybenzonitrile price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FH29690 | 3-Hydroxy-4-methoxybenzonitrile | 52805-46-6 | 0.25kg | $150 | 2026-06-04 | Buy |
| Biosynth | FH29690 | 3-Hydroxy-4-methoxybenzonitrile | 52805-46-6 | 0.05kg | $150 | 2026-06-04 | Buy |
| Biosynth | FH29690 | 3-Hydroxy-4-methoxybenzonitrile | 52805-46-6 | 0.5kg | $171.99 | 2026-06-04 | Buy |
| Biosynth | FH29690 | 3-Hydroxy-4-methoxybenzonitrile | 52805-46-6 | 1kg | $272.58 | 2026-06-04 | Buy |
| Apolloscientific | OR345595 | 3-Hydroxy-4-methoxy benzonitrile >98% | 52805-46-6 | 25g | $21 | 2026-06-04 | Buy |
3-Hydroxy-4-methoxybenzonitrile Chemical Properties, Uses, Production
Synthesis
621-59-0
52805-46-6
The general procedure for synthesizing 3-hydroxy-4-methoxybenzonitrile from isovanillin was as follows: 14.2 g of isovanillin was dissolved in 75 mL of formic acid, 15 g of sodium formate was added, and stirred at 85 °C. Subsequently, 9 g of hydroxylamine hydrochloride was added in batches, and the reaction mixture was kept at 85 °C and continued to be stirred for 4 hours. Upon completion of the reaction, the mixture was poured into a nearly saturated sodium chloride solution and a precipitate was precipitated. The precipitate was separated by filtration, washed sequentially with water and petroleum ether, and dried to give the product. The yield was 14.2 g. The yield was 93% of the theoretical value. The product was analyzed by HPLC-MS (Method D) with a retention time (Rt) of 1.18 min.
References
[1] Patent: WO2011/92128, 2011, A1. Location in patent: Page/Page column 37
[2] Patent: US2012/28939, 2012, A1. Location in patent: Page/Page column 18
[3] Patent: CN105330586, 2016, A. Location in patent: Paragraph 0055; 0056
[4] Patent: CN105461602, 2016, A. Location in patent: Paragraph 0049; 0050
[5] Molecules, 2017, vol. 22, # 10,
3-Hydroxy-4-methoxybenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from 3-Hydroxy-4-methoxybenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-14 | 3-Hydroxy-4-methoxybenzonitrile
52805-46-6
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co | |
![]() |
2019-07-06 | 3-Hydroxy-4-methoxybenzonitrile
52805-46-6
|
$8.00 | 1kg | 98% | 100KG | Career Henan Chemical Co |
-

- 3-Hydroxy-4-methoxybenzonitrile
52805-46-6
- $8.80
- 97%-99%
- Career Henan Chemical Co
-

- 3-Hydroxy-4-methoxybenzonitrile
52805-46-6
- $8.00
- 98%
- Career Henan Chemical Co





