TOSUFLOXACIN TOSILATE
- CAS No.
- 100490-36-6
- Chemical Name:
- TOSUFLOXACIN TOSILATE
- Synonyms
- Ozex;TFLX;a67107;a61827;A-60969;Toskisasin;Aids007807;Aids-007807;abbott61827;WUWFMDMBOJLQIV-UHFFFAOYSA-N
- CBNumber:
- CB5138403
- Molecular Formula:
- C19H15F3N4O3
- Molecular Weight:
- 404.34
- MDL Number:
- MFCD00865059
- MOL File:
- 100490-36-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 614.4±55.0 °C(Predicted) |
|---|---|
| Density | 1.558±0.06 g/cm3(Predicted) |
| pka | 5.79±0.70(Predicted) |
| InChI | InChI=1S/C19H15F3N4O3/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29) |
| InChIKey | WUWFMDMBOJLQIV-UHFFFAOYSA-N |
| SMILES | N1(C2=CC=C(F)C=C2F)C2C(=CC(F)=C(N3CCC(N)C3)N=2)C(=O)C(C(O)=O)=C1 |
| CAS DataBase Reference | 100490-36-6(CAS DataBase Reference) |
| FDA UNII | GHJ553KQPS |
TOSUFLOXACIN TOSILATE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ACHEMBLOCK | Y229645 | Tosufloxacin 97.00% | 100490-36-6 | 25MG | $240 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229645 | Tosufloxacin 97.00% | 100490-36-6 | 100MG | $480 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y229645 | Tosufloxacin 97.00% | 100490-36-6 | 500MG | $1120 | 2026-05-27 | Buy |
| Chemenu | CM140463 | 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 97% | 100490-36-6 | 1g | $287 | 2026-05-26 | Buy |
| aablocks | AA000217 | 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 98% | 100490-36-6 | 1g | $675 | 2026-05-25 | Buy |
TOSUFLOXACIN TOSILATE Chemical Properties, Uses, Production
Uses
Tosufloxacin Tosilate (CAS# 100490-36-6) was identified in a Haemophilus influenza clone ST422.
Definition
ChEBI: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively. It is a 1,8-naphthyridine derivative, an amino acid, a monocarboxylic acid, an organofluorine compound, an aminopyrrolidine, a tertiary amino compound, a primary amino compound and a quinolone antibiotic. It is a conjugate base of a 1-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]pyrrolidin-3-aminium.
in vivo
Tosufloxacin tosylate hydrate (T-3262) (oral gavage; 0.16-13.39 mg/kg; once) treatment shows antibacterial activity against S. aureus, E. coli, and P. aeruginosa in vivo[2].
| Animal Model: | Male Slc:ICR mice infected with S. aureus[2] |
| Dosage: | 1.27-2.15 mg/kg |
| Administration: | Oral gavage; 1.27-2.15 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 1.62 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.0125 μg/mL. |
| Animal Model: | Male Slc:ICR mice infected with E. coli[2] |
| Dosage: | 0.16-0.30 mg/kg |
| Administration: | Oral gavage; 0.16-0.30 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 0.22 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.0125 μg/mL. |
| Animal Model: | Male Slc:ICR mice infected with P. aeruginosa[2] |
| Dosage: | 7.66-13.39 mg/kg |
| Administration: | Oral gavage; 7.66-13.39 mg/kg; once |
| Result: | Showed 50% effective dose (ED50) of 10.13 mg/kg (body weight) at 7 days after infection. Showed MIC value of 0.78 μg/mL. |
IC 50
Quinolone
TOSUFLOXACIN TOSILATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
TOSUFLOXACIN TOSILATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Aikon International Limited | 025-58859352 15955137747 | sales01@aikonchem.com | China | 16021 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4183 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-025-85560043 17301488900 | info@synzest.com | China | 9274 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | helen.zhang@synzest.com | China | 8283 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Latest Price from TOSUFLOXACIN TOSILATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | TOSUFLOXACIN TOSILATE USP/EP/BP
100490-36-6
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-02-12 | TOSUFLOXACIN TOSILATE
100490-36-6
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- TOSUFLOXACIN TOSILATE USP/EP/BP
100490-36-6
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- TOSUFLOXACIN TOSILATE
100490-36-6
- $7.00
- 99%
- Career Henan Chemical Co
