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TOSUFLOXACIN TOSILATE

TOSUFLOXACIN TOSILATE Structure
TOSUFLOXACIN TOSILATE structure
CAS No.
100490-36-6
Chemical Name:
TOSUFLOXACIN TOSILATE
Synonyms
Ozex;TFLX;a67107;a61827;A-60969;Toskisasin;Aids007807;Aids-007807;abbott61827;WUWFMDMBOJLQIV-UHFFFAOYSA-N
CBNumber:
CB5138403
Molecular Formula:
C19H15F3N4O3
Molecular Weight:
404.34
MDL Number:
MFCD00865059
MOL File:
100490-36-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:56:55
Product description Number Pack Size Price
Tosufloxacin 97.00% Y229645 25MG $240
Tosufloxacin 97.00% Y229645 100MG $480
Tosufloxacin 97.00% Y229645 500MG $1120
7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 97% CM140463 1g $287
7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 98% AA000217 1g $675
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TOSUFLOXACIN TOSILATE Properties

Boiling point 614.4±55.0 °C(Predicted)
Density 1.558±0.06 g/cm3(Predicted)
pka 5.79±0.70(Predicted)
InChI InChI=1S/C19H15F3N4O3/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29)
InChIKey WUWFMDMBOJLQIV-UHFFFAOYSA-N
SMILES N1(C2=CC=C(F)C=C2F)C2C(=CC(F)=C(N3CCC(N)C3)N=2)C(=O)C(C(O)=O)=C1
CAS DataBase Reference 100490-36-6(CAS DataBase Reference)
FDA UNII GHJ553KQPS

TOSUFLOXACIN TOSILATE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ACHEMBLOCK Y229645 Tosufloxacin 97.00% 100490-36-6 25MG $240 2026-05-27 Buy
ACHEMBLOCK Y229645 Tosufloxacin 97.00% 100490-36-6 100MG $480 2026-05-27 Buy
ACHEMBLOCK Y229645 Tosufloxacin 97.00% 100490-36-6 500MG $1120 2026-05-27 Buy
Chemenu CM140463 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 97% 100490-36-6 1g $287 2026-05-26 Buy
aablocks AA000217 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 98% 100490-36-6 1g $675 2026-05-25 Buy
Product number Packaging Price Buy
Y229645 25MG $240 Buy
Y229645 100MG $480 Buy
Y229645 500MG $1120 Buy
CM140463 1g $287 Buy
AA000217 1g $675 Buy

TOSUFLOXACIN TOSILATE Chemical Properties,Uses,Production

Uses

Tosufloxacin Tosilate (CAS# 100490-36-6) was identified in a Haemophilus influenza clone ST422.

Definition

ChEBI: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid is a 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 3-aminopyrrolidin-1-yl substituents at positions 1, 6 and 7 respectively. It is a 1,8-naphthyridine derivative, an amino acid, a monocarboxylic acid, an organofluorine compound, an aminopyrrolidine, a tertiary amino compound, a primary amino compound and a quinolone antibiotic. It is a conjugate base of a 1-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]pyrrolidin-3-aminium.

in vivo

Tosufloxacin tosylate hydrate (T-3262) (oral gavage; 0.16-13.39 mg/kg; once) treatment shows antibacterial activity against S. aureus, E. coli, and P. aeruginosa in vivo[2].

Animal Model:Male Slc:ICR mice infected with S. aureus[2]
Dosage:1.27-2.15 mg/kg
Administration:Oral gavage; 1.27-2.15 mg/kg; once
Result:Showed 50% effective dose (ED50) of 1.62 mg/kg (body weight) at 7 days after infection.
Showed MIC value of 0.0125 μg/mL.
Animal Model:Male Slc:ICR mice infected with E. coli[2]
Dosage:0.16-0.30 mg/kg
Administration:Oral gavage; 0.16-0.30 mg/kg; once
Result:Showed 50% effective dose (ED50) of 0.22 mg/kg (body weight) at 7 days after infection.
Showed MIC value of 0.0125 μg/mL.
Animal Model:Male Slc:ICR mice infected with P. aeruginosa[2]
Dosage:7.66-13.39 mg/kg
Administration:Oral gavage; 7.66-13.39 mg/kg; once
Result:Showed 50% effective dose (ED50) of 10.13 mg/kg (body weight) at 7 days after infection.
Showed MIC value of 0.78 μg/mL.

IC 50

Quinolone

TOSUFLOXACIN TOSILATE Preparation Products And Raw materials

Raw materials

2-Chloropyridine-N-oxide p-Toluenesulfonic acid Ethyl fluoroacetate Tosufloxacin Glycine
2,4-Difluoroaniline 3-Aminopyrrolidine Pyrrolidine

1of2

Preparation Products

TOSUFLOXACIN TOSILATE Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 20582 58
Alfa Chemistry 		+1-5166625404; Info@alfa-chemistry.com United States 20405 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 24597 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2123 70
Aikon International Limited 025-58859352 15955137747 sales01@aikonchem.com China 16027 58
Chengdu Saint - Kay Biotechnology Co., Ltd. 028-85157043 15882256948 676046971@qq.com China 4191 58
Supplier Advantage
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Dideu Industries Group Limited 		58
Alfa Chemistry 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Mainchem Co., Ltd. 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
LGM Pharma 70
Aikon International Limited 58
Chengdu Saint - Kay Biotechnology Co., Ltd. 58

View Lastest Price from TOSUFLOXACIN TOSILATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TOSUFLOXACIN TOSILATE USP/EP/BP pictures 2025-11-18 TOSUFLOXACIN TOSILATE USP/EP/BP
100490-36-6
 $1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
TOSUFLOXACIN TOSILATE pictures 2020-02-12 TOSUFLOXACIN TOSILATE
100490-36-6
 $7.00 1KG 99% 100KG Career Henan Chemical Co

100490-36-6(TOSUFLOXACIN TOSILATE)Related Search:

Tosufloxacin Norfloxacin Tosufloxacin tosilate ETHYL7-(3-AMINO-1-PYRROLIDINYL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLATE TOSUFLOXACIN TOSILATE
1,8-naphthyridine-3-carboxylicacid,1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-( 4-difluorophenyl)-6-fluoro-4-oxo- a61827 a67107 1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-aminopyrrolidin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- (9CI) A-60969 Ozex Toskisasin 7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 7-(3-Aminopyrrolizino)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid TFLX 7-(3-Amino-1-pyrrolidinyl-1-(2,4-diflurophenyl)-6-fluro-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid Aids007807 Aids-007807 WUWFMDMBOJLQIV-UHFFFAOYSA-N (+)-7-(3-Amino-1-pyrrolidinyl)-6-fluoro-1-(2，4-difluo-rophenyl)-1，4-dihydrcr-4-oxo-1，8-naphthyridine-3-carboxyli cacid abbott61827 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- TOSUFLOXACIN TOSILATE USP/EP/BP Lactide Impurity 2 (DL-Lactide) 100490-36-6 C19H15F3N4O3SC7H8O3S C19H15F3N4O3C7H8O3S C19H15F3N4O3