Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(+)-LARICIRESINOL

(+)-LARICIRESINOL

(+)-LARICIRESINOL Structure
(+)-LARICIRESINOL structure
CAS No.
27003-73-2
Chemical Name:
(+)-LARICIRESINOL
Synonyms
LARICIRESINOL;Nsc329247;Lariciresil;Laricericinol;Larch resinol;(+)-LARICIRESINOL;Lariciresinol, 10 mM in DMSO;inhibit,Inhibitor,Lariciresinol;(2S)-2α-(3-Methoxy-4-hydroxyphenyl)-4β-(3-methoxy-4-hydroxybenzyl)tetrahydrofuran-3β-methanol;2α-(4-Hydroxy-3-methoxyphenyl)-3β-(hydroxymethyl)-4β-(4-hydroxy-3-methoxybenzyl)tetrahydrofuran
CBNumber:
CB5223646
Molecular Formula:
C20H24O6
Molecular Weight:
360.4
MDL Number:
MFCD07784476
MOL File:
27003-73-2.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
Request For Quotation

(+)-LARICIRESINOL Properties

Melting point 167-168 °C
Boiling point 568.4±50.0 °C(Predicted)
Density 1.261±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 9.91±0.35(Predicted)
color White to off-white
BRN 4560057
Major Application metabolomics
vitamins, nutraceuticals, and natural products
InChI InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1
InChIKey MHXCIKYXNYCMHY-AUSJPIAWSA-N
SMILES O1C[C@H](CC2=CC=C(O)C(OC)=C2)[C@H](CO)[C@H]1C1=CC=C(O)C(OC)=C1
LogP 1.640 (est)
FDA UNII 73XCE5OZB0
UNSPSC Code 12352005
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273-P391-P501
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Acute 1

(+)-LARICIRESINOL price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 06892 (+)-Lariciresinol ≥95.0% (HPLC) 27003-73-2 10mg $1120 2026-04-30 Buy
Biosynth FL71884 (+)-Lariciresinol 27003-73-2 1mg $278.65 2026-06-04 Buy
Biosynth FL71884 (+)-Lariciresinol 27003-73-2 2mg $512.7 2026-06-04 Buy
Biosynth FL71884 (+)-Lariciresinol 27003-73-2 5mg $1058.85 2026-06-04 Buy
Biosynth FL71884 (+)-Lariciresinol 27003-73-2 10mg $1671.9 2026-06-04 Buy
Product number Packaging Price Buy
06892 10mg $1120 Buy
FL71884 1mg $278.65 Buy
FL71884 2mg $512.7 Buy
FL71884 5mg $1058.85 Buy
FL71884 10mg $1671.9 Buy

(+)-LARICIRESINOL Chemical Properties, Uses, Production

Uses

(+)-Lariciresinol is used in biological studies as an anti-tumor-initiating effects of phenolic compounds isolated from the bark of Picea jezoensis var. jezoensis to evaluate the pharmacological activity.

Definition

ChEBI: (+)-lariciresinol is a lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer). It has a role as an antifungal agent and a plant metabolite. It is a member of oxolanes, a member of phenols, a lignan, a primary alcohol and an aromatic ether. It is an enantiomer of a (-)-lariciresinol.

Biological Activity

Lariciresinol is a potent dietary antioxidant and a radical scavenger by potentially chelating catalytic Fe2+ ions. It exerts antimicrobial effects against foodborne pathogens S. aureus and E. coli O157:H7. Lariciresinol is an effective anticancer agent th at inhibits cell proliferation and induces apoptosis in human HepG2 cells in vitro. It also displays anti-inflammatory and anti-diabetic effects in vitro and in vivo studies respectively.

in vivo

Lariciresinol (10 mg/kg, p.o., 3 weeks) displays anti-diabetic activity in Streptozotocin (HY-13753)-treated diabetic mice[6].
Lariciresinol (10-30 mg/kg, i.p., 28 days) inhibits complete Freund's adjuvant-induced arthritis in rats by regulating TGF-β and NF-κB pathways[7].
Lariciresinol (3-15 mg/kg body weight, p.o., daily, 9 weeks (tumor bearing rats); 20-100 ppm, diet, p.o., 5 weeks (E2-maintained ovariectomized athymic mice bearing orthotopic MCF-7 tumors)) inhibits tumor growth and tumor angiogenesis in mammary tumor bearing rats and E2-maintained ovariectomized athymic mice bearing orthotopic MCF-7 tumors[8].

Animal Model:Streptozotocin (HY-13753)-treated diabetic mice[6]
Dosage:10 mg/kg
Administration:Oral gavage (p.o.), 3 weeks
Result:Decreased blood glucose levels and increased insulin levels.
Improved pancreatic islet size, increased GLUT4 expression.
Enhanced insulin signaling in skeletal muscle.

target

VEGFR | Antifection

(+)-LARICIRESINOL Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-LARICIRESINOL Suppliers

Global Suppliers ( 113)
Supplier Tel Email Country ProdList Advantage
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449;13124863828 2630597085@qq.com China 1885 55
Supplier Advantage
BioBioPha Co., Ltd. 65
Chembest Research Laboratories Limited 61
Nanjing Chemlin Chemical Co., Ltd 64
Chengdu Biopurify Phytochemicals Ltd. 60
Bide Pharmatech Ltd. 60
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Shanghai Yongye Biotechnology Co., Ltd. 55
Sigma-Aldrich 80
Tongling HengYou Biotechnology Co., Ltd. 55

View Latest Price from (+)-LARICIRESINOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Lariciresinol pictures 2026-07-27 Lariciresinol
27003-73-2
 $172.00-433.00 99.96% 10g TargetMol Chemicals Inc.
(+)-LARICIRESINOL pictures 2026-06-30 (+)-LARICIRESINOL
27003-73-2
 1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
Lariciresinol pictures 2023-02-24 Lariciresinol
27003-73-2
 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Lariciresinol pictures
  • Lariciresinol
    27003-73-2
  • $172.00-433.00
  • 99.96%
  • TargetMol Chemicals Inc.
  • Lariciresinol pictures
  • Lariciresinol
    27003-73-2
  • $0.00
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.

(+)-LARICIRESINOL Spectrum

(+)-LARICIRESINOL(27003-73-2)1HNMR

27003-73-2 ((+)-LARICIRESINOL) Related Search:

2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Cyperone beta-Sitosterol beta-Eudesmol Artemether
Asarinin Sesamin magnolin (+)-PINORESINOL ELEUTHEROSIDE E1
PINORESINOL DIGLUCOSIDE(P)(PLEASE CALL) (+)-Epipinoresinol FARGESIN (+)-LARICIRESINOL (+)-Syringaresinol
CLEMASTANIN B (1S,3aR,4S,6aR)-1,4-Bis(3,4-dimethoxyphenyl)-hexahydrofuro[3,4-c]furan (+)-SYLVATESMIN

1of4

(2S)-2α-(3-Methoxy-4-hydroxyphenyl)-4β-(3-methoxy-4-hydroxybenzyl)tetrahydrofuran-3β-methanol (2S)-Tetrahydro-2α-(4-hydroxy-3-methoxyphenyl)-4β-[(4-hydroxy-3-methoxyphenyl)methyl]-3β-furanmethanol 2-Methoxy-4-[[(2S)-tetrahydro-2α-(3-methoxy-4-hydroxyphenyl)-3β-(hydroxymethyl)furan-4β-yl]methyl]phenol 2α-(4-Hydroxy-3-methoxyphenyl)-3β-(hydroxymethyl)-4β-(4-hydroxy-3-methoxybenzyl)tetrahydrofuran Laricericinol Nsc329247 Lariciresil (+)-LARICIRESINOL (2S,3R,4R)-Tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-furanmethanol 4-[(2S,3R,4R)-4-[(4-Hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]-2-methoxyphenol 3-Furanmethanol,tetrahydro-2-(4-hydroxy-3-methoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-,(2S,3R,4R)- 4-((2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methoxyphenol inhibit,Inhibitor,Lariciresinol Larch resinol Lariciresinol, 10 mM in DMSO LARICIRESINOL 27003-73-2 Miscellaneous Natural Products