4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde
- CAS No.
- 33097-11-9
- Chemical Name:
- 4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde
- Synonyms
- ASISCHEM C51986;2-Aminomethylimidazoledihydrochloride;4,6-DICHLORO-2-(METHYLTHIO)-5-FORMYLPYRIMIDINE;2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARB;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarbaldehyde;4,6-Dichloro-2-(methylthio)pyrimidine-5-carbaldehyde;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde;2-(Methylthio)-4,6-dichloropyriMidine-5-carboxaldehyde
- CBNumber:
- CB5225675
- Molecular Formula:
- C6H4Cl2N2OS
- Molecular Weight:
- 223.08
- MDL Number:
- MFCD00194954
- MOL File:
- 33097-11-9.mol
- MSDS File:
- SDS
| Melting point | 82-84°C |
|---|---|
| Boiling point | 327.7±37.0 °C(Predicted) |
| Density | 1.57±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform, Ether, Ethyl Acetate |
| form | Solid |
| pka | -6.47±0.39(Predicted) |
| color | Pale Yellow |
| InChI | InChI=1S/C6H4Cl2N2OS/c1-12-6-9-4(7)3(2-11)5(8)10-6/h2H,1H3 |
| InChIKey | MRHGOAKYYORQGQ-UHFFFAOYSA-N |
| SMILES | C1(SC)=NC(Cl)=C(C=O)C(Cl)=N1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 759279 | 4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxaldehyde 97% | 33097-11-9 | 1g | $72 | 2023-06-20 | Buy |
| Usbiological | D3531-35 | 4,6-Dichloro-2-(methylthio)-5-formylpyrimidine | 250mg | $333 | 2026-06-03 | Buy | |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 1g | $460 | 2026-06-03 | Buy |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 2g | $602 | 2026-06-03 | Buy |
4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde Chemical Properties, Uses, Production
Chemical Properties
Pale Yellow Solid
Uses
4,6-Dichloro-2-(methylthio)-5-formylpyrimidine (cas# 33097-11-9) is a compound useful in organic synthesis.
Synthesis
1979-98-2
33097-11-9
The general procedure for the synthesis of 4,6-dichloro-2-methylthiopyrimidine-5-carbaldehyde from 4,6-dihydroxy-2-methylthiopyrimidine was as follows: the reaction system was cooled down to 0-10 °C and then slowly warmed up to room temperature. Subsequently, 6-hydroxy-2-(methylthio)-4(1H)-pyrimidinone (25 g, 0.16 mol) was added in batches. The reaction mixture was heated and reacted at 80 °C overnight. After completion of the reaction, the reaction mixture was concentrated under vacuum. The concentrated slurry residue was poured into ice and stirred continuously for about 2 hours, after which filtration was performed to obtain the crude product. The crude product was further purified by recrystallization with hexane to afford finally 4,6-dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde (21.3 g, 61% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ 2.66 (s, 3H), 10.4 (s, 1H).
References
[1] Patent: WO2006/104889, 2006, A2. Location in patent: Page/Page column 113-114
[2] Patent: WO2007/147103, 2007, A2. Location in patent: Page/Page column 107-108
4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 | info@rovathin.com.cn | China | 9961 | 58 |
| Awesome （Beijing）TechnologyCo.,Ltd. | 18201687790 18201687790 | yunbo12291229@163.com | China | 137 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
View Latest Price from 4,6-Dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-09 | 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
|
$5.50 | 1KG | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
- $5.50
- 98%min
- Career Henan Chemical Co
