4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
- CAS No.
- 33097-11-9
- Chemical Name:
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
- Synonyms
- ASISCHEM C51986;2-Aminomethylimidazoledihydrochloride;4,6-DICHLORO-2-(METHYLTHIO)-5-FORMYLPYRIMIDINE;2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARB;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarbaldehyde;4,6-Dichloro-2-(methylthio)pyrimidine-5-carbaldehyde;2-(Methylthio)-4,6-dichloropyriMidine-5-carboxaldehyde;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde
- CBNumber:
- CB5225675
- Molecular Formula:
- C6H4Cl2N2OS
- Molecular Weight:
- 223.08
- MDL Number:
- MFCD00194954
- MOL File:
- 33097-11-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxaldehyde 97% | 759279 | 1g | $72 |
| 4,6-Dichloro-2-(methylthio)-5-formylpyrimidine | D3531-35 | 250mg | $333 |
| 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 270861 | 500mg | $333 |
| 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 270861 | 1g | $460 |
| 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 270861 | 2g | $602 |
| More product size | |||
| Melting point | 82-84°C |
|---|---|
| Boiling point | 327.7±37.0 °C(Predicted) |
| Density | 1.57±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform, Ether, Ethyl Acetate |
| form | Solid |
| pka | -6.47±0.39(Predicted) |
| color | Pale Yellow |
| InChI | InChI=1S/C6H4Cl2N2OS/c1-12-6-9-4(7)3(2-11)5(8)10-6/h2H,1H3 |
| InChIKey | MRHGOAKYYORQGQ-UHFFFAOYSA-N |
| SMILES | C1(SC)=NC(Cl)=C(C=O)C(Cl)=N1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 759279 | 4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxaldehyde 97% | 33097-11-9 | 1g | $72 | 2023-06-20 | Buy |
| Usbiological | D3531-35 | 4,6-Dichloro-2-(methylthio)-5-formylpyrimidine | 250mg | $333 | 2026-06-03 | Buy | |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 1g | $460 | 2026-06-03 | Buy |
| Usbiological | 270861 | 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine Asreported | 33097-11-9 | 2g | $602 | 2026-06-03 | Buy |
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Solid
Uses
4,6-Dichloro-2-(methylthio)-5-formylpyrimidine (cas# 33097-11-9) is a compound useful in organic synthesis.
Synthesis
1979-98-2
33097-11-9
The general procedure for the synthesis of 4,6-dichloro-2-methylthiopyrimidine-5-carbaldehyde from 4,6-dihydroxy-2-methylthiopyrimidine was as follows: the reaction system was cooled down to 0-10 °C and then slowly warmed up to room temperature. Subsequently, 6-hydroxy-2-(methylthio)-4(1H)-pyrimidinone (25 g, 0.16 mol) was added in batches. The reaction mixture was heated and reacted at 80 °C overnight. After completion of the reaction, the reaction mixture was concentrated under vacuum. The concentrated slurry residue was poured into ice and stirred continuously for about 2 hours, after which filtration was performed to obtain the crude product. The crude product was further purified by recrystallization with hexane to afford finally 4,6-dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde (21.3 g, 61% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ 2.66 (s, 3H), 10.4 (s, 1H).
References
[1] Patent: WO2006/104889, 2006, A2. Location in patent: Page/Page column 113-114
[2] Patent: WO2007/147103, 2007, A2. Location in patent: Page/Page column 107-108
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29793 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29120 | 58 |
View Lastest Price from 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-09 | 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
|
$5.50 | 1KG | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
33097-11-9
- $5.50
- 98%min
- Career Henan Chemical Co
