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L-alpha-Cyclohexylglycine

CAS No.
14328-51-9
Chemical Name:
L-alpha-Cyclohexylglycine
Synonyms
L-CHG-OH;EOS-60419;-(+)-2-CycL;L-Chg-OH·HCl;H-CHG-OH TFA;L-Chg-OH·TFA;H-CHG-OH HCL;H-CHG-OET HCL;H-L-Chg-OH*HCl;L-Cyclohexyglycine
CBNumber:
CB5273131
Molecular Formula:
C8H15NO2
Molecular Weight:
157.21
MDL Number:
MFCD01311679
MOL File:
14328-51-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:24
Product description Number Pack Size Price
L-2-Cyclohexylglycine >98.0%(HPLC)(T) C2569 1g $30
L-2-Cyclohexylglycine >98.0%(HPLC)(T) C2569 5g $203
2-CYCLOHEXYL-L-GLYCINE 97% 59684 100G $45
(S)-2-amino-2-cyclohexylacetic acid >98% A66203 100g $70
(S)-2-amino-2-cyclohexylacetic acid >98% A66203 500g $280
More product size

L-alpha-Cyclohexylglycine Properties

Melting point 256°C
alpha 34.5 º (c=1, 1N HCl 25 ºC)
Boiling point 292.8±23.0 °C(Predicted)
Density 1.120±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka 2.44±0.10(Predicted)
form powder to crystal
color White to Almost white
Water Solubility Soluble
InChI InChI=1/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/s3
InChIKey WAMWSIDTKSNDCU-ZETCQYMHSA-N
SMILES C1(CCCCC1)[C@H](N)C(=O)O |&1:6,r|
CAS DataBase Reference 14328-51-9(CAS DataBase Reference)
FDA UNII 59Q5O5615E

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25
HS Code  29224999
NFPA 704
1
2 0

L-alpha-Cyclohexylglycine price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2569 L-2-Cyclohexylglycine >98.0%(HPLC)(T) 14328-51-9 1g $30 2026-04-30 Buy
TCI Chemical C2569 L-2-Cyclohexylglycine >98.0%(HPLC)(T) 14328-51-9 5g $203 2023-06-20 Buy
AstaTech 59684 2-CYCLOHEXYL-L-GLYCINE 97% 14328-51-9 100G $45 2026-04-30 Buy
Synthonix A66203 (S)-2-amino-2-cyclohexylacetic acid >98% 14328-51-9 100g $70 2026-05-06 Buy
Synthonix A66203 (S)-2-amino-2-cyclohexylacetic acid >98% 14328-51-9 500g $280 2026-05-06 Buy
Product number Packaging Price Buy
C2569 1g $30 Buy
C2569 5g $203 Buy
59684 100G $45 Buy
A66203 100g $70 Buy
A66203 500g $280 Buy

L-alpha-Cyclohexylglycine Chemical Properties,Uses,Production

Chemical Properties

white to slightly beige powder

Uses

L-Alpha-cyclohexylglycine is used in the preparation of α-aminoalkanoic acids.

Synthesis

L-Phenylglycine

2935-35-5

L-alpha-Cyclohexylglycine

14328-51-9

The general procedure for the synthesis of L-(+)-2-cyclohexylglycine from L-phenylglycine is as follows: the selective hydrogenation of optically active phenyl amino acids is carried out in a 100 ml stainless steel autoclave equipped with a magnetic stirring device. Prior to the addition of catalyst, the autoclave is purged three times with hydrogen gas to remove air completely. Under the protection of inert atmosphere, a suspension of freshly prepared nanoruthenium(at)lithium montmorillonite catalyst (containing 0.01592 mmol Ru, dissolved in 10 ml of H2O) was carefully transferred to the autoclave together with an appropriate amount of substrate, and then the autoclave was charged with hydrogen gas to a set pressure. The autoclave was placed in a preheated heating jacket, magnetic stirring was activated, and the reaction lasted for the specified time. At the end of the reaction, the autoclave was allowed to cool to room temperature and the internal pressure was slowly released. Thoroughly rinse the inside of the reactor with 2N NaOH solution to recover the products (if the reaction system is acidic, switch to 2N HCl solution). All collected solutions were filtered through a 0.22 μm PTFE membrane to remove the catalyst residue, followed by adjusting the pH of the filtrate with dilute HCl (or NaOH) solution to 5.5, at which point the products partially precipitated. The suspension was concentrated to 10 ml under vacuum to induce complete precipitation of the product. The precipitate was collected by filtration, washed with distilled water and finally dried under vacuum for 24 hours.

References

[1] Organic Process Research and Development, 2003, vol. 7, # 2, p. 164 - 167
[2] Journal of Organometallic Chemistry, 2016, vol. 812, p. 81 - 86
[3] Synthetic Communications, 1999, vol. 29, # 24, p. 4327 - 4332
[4] Journal of Medicinal Chemistry, 1993, vol. 36, # 1, p. 166 - 172

103-01-5
14328-51-9
Synthesis of L-alpha-Cyclohexylglycine from Anilinoacetic acid
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View Lastest Price from L-alpha-Cyclohexylglycine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-CHG-OH pictures 2026-05-15 L-CHG-OH
14328-51-9
US $0.00 / Kg/Drum 1KG 99%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
H-Chg-OH pictures 2026-05-14 H-Chg-OH
14328-51-9
US $0.00-0.00 / kg 1kg 99% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
L-alpha-Cyclohexylgycine pictures 2021-07-13 L-alpha-Cyclohexylgycine
14328-51-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • L-CHG-OH pictures
  • L-CHG-OH
    14328-51-9
  • US $0.00 / Kg/Drum
  • 99%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • H-Chg-OH pictures
  • H-Chg-OH
    14328-51-9
  • US $0.00-0.00 / kg
  • 99%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
(S)-CYCLOHEXYLGLYCINE HCL H-L-Cyclohexyl-Gly-OH·TFA L-2-Cyclohexylglycine trifluoroacetate≥ 99% (TLC) L-Chg-OH·TFA H-Cyclohexyl-L-Gly-OH·HCl L-(+)-2-Cyclohexylglycine hydrochloride≥ 99% (Titration) L-Chg-OH·HCl L-Cyclohexylglycine,99%e.e. H-CHG-OH TFA H-PHG(HEXAHYDRO)-OH HCL H-CYCLOHEXYL-GLY-OH HCL H-CYCLOHEXYL-GLY-OH TFA H-CHG-OH HCL HEXAHYDRO-L-PHENYLGLYCINE HYDROCHLORIDE H-L-Chg-OH*HCl H-Cyclohexyl-Gly-OH (H-Chg-OH: L-2-Cyclohexylglycine) L-alpha-Cyclohexylglycine,97% H-Cyclohexyl-Gly-OH (H-Chg-OH (S)-Cyclohexylglycine hydrochloride L-2-CYCLOHEXYLGLYCINE HYDROCHLORIDE L-2-CYCLOHEXYLGLYCINE TRIFLUOROACETATE L-ALPHA-CYCLOHEXYLGLYCINE HYDROCHLORIDE SALT L-ALPHA-CYCLOHEXYLGYCINE HYDROCHLORIDE SALT L-CYCLOHEXYLGLYCINE HYDROCHLORIDE L-Cyclohexyglycine L-CYCLOHEXYLGLYCINE 98% L-a-cyclobenzyl glycine (S)-(-)-alpha-Aminocyclohexylacetic acid L-alpha-Cyclohexylglycine AMINO-CYCLOHEXYL-ACE L-alpha-Cyclohexylglycine, 97% 5GR H-CHG-OET HCL (S)-alpha-Aminocyclohexylacetic Acid H-Chg-OH L-Cyclohexylglycine, H-Chg-OH L-CHG-OH Cyclohexaneacetic acid,a-aMino-, (aS)- L-(+)-2-Cyclohexylglycine, 95+% EOS-60419 L-2-Cyclohexylglycine > Cyclohexaneacetic acid, α-amino-, (αS)- -(+)-2-CycL L-alpha-Cyclohexylglycine USP/EP/BP L-alpha-Cyclohexylgycine L-α-cyclohexylglycine (αS)-α-Aminocyclohexaneacetic acid (alphaS)-alpha-Aminocyclohexaneacetic acid 14328-51-9 Glycine [Gly, G] API pharmacetical