L-alpha-Cyclohexylglycine
- CAS No.
- 14328-51-9
- Chemical Name:
- L-alpha-Cyclohexylglycine
- Synonyms
- L-CHG-OH;EOS-60419;-(+)-2-CycL;L-Chg-OH·HCl;H-CHG-OH TFA;L-Chg-OH·TFA;H-CHG-OH HCL;H-CHG-OET HCL;H-L-Chg-OH*HCl;L-Cyclohexyglycine
- CBNumber:
- CB5273131
- Molecular Formula:
- C8H15NO2
- Molecular Weight:
- 157.21
- MDL Number:
- MFCD01311679
- MOL File:
- 14328-51-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 256°C |
|---|---|
| alpha | 34.5 º (c=1, 1N HCl 25 ºC) |
| Boiling point | 292.8±23.0 °C(Predicted) |
| Density | 1.120±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder to crystal |
| pka | 2.44±0.10(Predicted) |
| color | White to Almost white |
| Water Solubility | Soluble |
| InChI | InChI=1/C8H15NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h6-7H,1-5,9H2,(H,10,11)/t7-/s3 |
| InChIKey | WAMWSIDTKSNDCU-ZETCQYMHSA-N |
| SMILES | C1(CCCCC1)[C@H](N)C(=O)O |&1:6,r| |
| CAS DataBase Reference | 14328-51-9(CAS DataBase Reference) |
| FDA UNII | 59Q5O5615E |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| HS Code | 29224999 | |||||||||
| NFPA 704 |
|
L-alpha-Cyclohexylglycine price More Price(83)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2569 | L-2-Cyclohexylglycine >98.0%(HPLC)(T) | 14328-51-9 | 1g | $30 | 2026-04-30 | Buy |
| TCI Chemical | C2569 | L-2-Cyclohexylglycine >98.0%(HPLC)(T) | 14328-51-9 | 5g | $203 | 2023-06-20 | Buy |
| Usbiological | 269546 | L-a-Cyclohexylglycine Asreported | 14328-51-9 | 10g | $378 | 2026-06-03 | Buy |
| Usbiological | 269546 | L-a-Cyclohexylglycine Asreported | 14328-51-9 | 25g | $526 | 2026-06-03 | Buy |
| Usbiological | 269546 | L-a-Cyclohexylglycine Asreported | 14328-51-9 | 50g | $721 | 2026-06-03 | Buy |
L-alpha-Cyclohexylglycine Chemical Properties, Uses, Production
Chemical Properties
white to slightly beige powder
Uses
L-Alpha-cyclohexylglycine is used in the preparation of α-aminoalkanoic acids.
Synthesis
2935-35-5
14328-51-9
The general procedure for the synthesis of L-(+)-2-cyclohexylglycine from L-phenylglycine is as follows: the selective hydrogenation of optically active phenyl amino acids is carried out in a 100 ml stainless steel autoclave equipped with a magnetic stirring device. Prior to the addition of catalyst, the autoclave is purged three times with hydrogen gas to remove air completely. Under the protection of inert atmosphere, a suspension of freshly prepared nanoruthenium(at)lithium montmorillonite catalyst (containing 0.01592 mmol Ru, dissolved in 10 ml of H2O) was carefully transferred to the autoclave together with an appropriate amount of substrate, and then the autoclave was charged with hydrogen gas to a set pressure. The autoclave was placed in a preheated heating jacket, magnetic stirring was activated, and the reaction lasted for the specified time. At the end of the reaction, the autoclave was allowed to cool to room temperature and the internal pressure was slowly released. Thoroughly rinse the inside of the reactor with 2N NaOH solution to recover the products (if the reaction system is acidic, switch to 2N HCl solution). All collected solutions were filtered through a 0.22 μm PTFE membrane to remove the catalyst residue, followed by adjusting the pH of the filtrate with dilute HCl (or NaOH) solution to 5.5, at which point the products partially precipitated. The suspension was concentrated to 10 ml under vacuum to induce complete precipitation of the product. The precipitate was collected by filtration, washed with distilled water and finally dried under vacuum for 24 hours.
References
[1] Organic Process Research and Development, 2003, vol. 7, # 2, p. 164 - 167
[2] Journal of Organometallic Chemistry, 2016, vol. 812, p. 81 - 86
[3] Synthetic Communications, 1999, vol. 29, # 24, p. 4327 - 4332
[4] Journal of Medicinal Chemistry, 1993, vol. 36, # 1, p. 166 - 172
L-alpha-Cyclohexylglycine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan zhongdaoanran chemical Co;Ltd | 18678233466; 18678233466 | 122574856@qq.com | China | 195 | 58 |
| Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 15366717810 | sales@thbiochem.com | China | 407 | 55 |
| Shandong Shining Pharm Co.,Ltd | 18866891188 18866891188 | zhaojiangxia@shiningpharm.com | China | 203 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
View Latest Price from L-alpha-Cyclohexylglycine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | H-Chg-OH
14328-51-9
|
1kg | 99% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-09-16 | L-CHG-OH
14328-51-9
|
1KG | 99%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2021-07-13 | L-alpha-Cyclohexylgycine
14328-51-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- H-Chg-OH
14328-51-9
- 99%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- L-CHG-OH
14328-51-9
- $0.00
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- L-alpha-Cyclohexylgycine
14328-51-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
