3-Amino-5-trifluoromethyl-benzoic acid methyl ester
- CAS No.
- 22235-25-2
- Chemical Name:
- 3-Amino-5-trifluoromethyl-benzoic acid methyl ester
- Synonyms
- METHYL 3-AMINO-5-(TRIFLUOROMETHYL)BENZOATE;BUTTPARK 88\11-03;3-Amino-5-trifluoromethyl-benzoic acid methyl ester;Benzoic acid, 3-amino-5-(trifluoromethyl)-, methyl ester
- CBNumber:
- CB5313657
- Molecular Formula:
- C9H8F3NO2
- Molecular Weight:
- 219.16
- MDL Number:
- MFCD00625827
- MOL File:
- 22235-25-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H315-H319-H341-H227 |
| Precautionary statements | P501-P261-P270-P202-P210-P201-P271-P264-P280-P370+P378-P308+P313-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P403+P235-P405 |
| HS Code | 2916399090 |
3-Amino-5-trifluoromethyl-benzoic acid methyl ester price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FM105578 | Methyl 3-amino-5-(trifluoromethyl)benzoate | 22235-25-2 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FM105578 | Methyl 3-amino-5-(trifluoromethyl)benzoate | 22235-25-2 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | FM105578 | Methyl 3-amino-5-(trifluoromethyl)benzoate | 22235-25-2 | 25g | $900 | 2026-06-04 | Buy |
| Biosynth | FM105578 | Methyl 3-amino-5-(trifluoromethyl)benzoate | 22235-25-2 | 1g | $900 | 2026-06-04 | Buy |
| Biosynth | FM105578 | Methyl 3-amino-5-(trifluoromethyl)benzoate | 22235-25-2 | 10g | $900 | 2026-06-04 | Buy |
3-Amino-5-trifluoromethyl-benzoic acid methyl ester Chemical Properties, Uses, Production
Synthesis
22227-63-0
22235-25-2
General procedure for the synthesis of methyl 3-amino-5-(trifluoromethyl)benzoate from methyl 3-nitro-5-trifluoromethylbenzoate: to a solution of methyl 3-nitro-5-(trifluoromethyl)benzoate (350 mg, 1.40 mmol) and tin(II) chloride dihydrate (1.58 g, 7.02 mmol) in methanol (20 mL) was added water (1 mL). The reaction mixture was stirred at 70 °C for 2 hours. After completion of the reaction, it was cooled to room temperature, the reaction solution was concentrated and quenched with saturated sodium bicarbonate solution. The reaction mixture was extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to afford methyl 3-amino-5-(trifluoromethyl)benzoate (300 mg, 98% yield) as a colorless solid.1H NMR (400 MHz, CDCl3): δ 7.65 (s, 1H), 7.48 (s, 1H), 7.05 (s, 1H), 3.99 (br s, 2H), 3.91 (s, 3H).
References
[1] Patent: WO2012/37132, 2012, A1. Location in patent: Page/Page column 47
[2] Patent: WO2007/4749, 2007, A1. Location in patent: Page/Page column 125
[3] Patent: US2012/71489, 2012, A1. Location in patent: Page/Page column 59
[4] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 72
[5] Patent: WO2008/9435, 2008, A1. Location in patent: Page/Page column 159; 160
3-Amino-5-trifluoromethyl-benzoic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-5-trifluoromethyl-benzoic acid methyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 3014 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Na Qian Chemical Technology Co. Ltd. | 13598610367 13598610367 | 2841375912@qq.com | China | 3787 | 52 |
View Latest Price from 3-Amino-5-trifluoromethyl-benzoic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-25 | 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER
22235-25-2
|
$1.00 | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-
- 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER
22235-25-2
- $1.00
- 99%
- Career Henan Chemical Co
