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1-Acetylindoline

1-Acetylindoline Structure
1-Acetylindoline structure
CAS No.
16078-30-1
Chemical Name:
1-Acetylindoline
Synonyms
1-ACETYL-2,3-DIHYDROINDOLE;1-(indolin-1-yl)ethan-1-one;1-acetyl-indolin;1-Acetylindoline;N-ACETYL INDOLINE;Acetylindoline,N-;1-ACETYLINDOLINE 98+%;1-acetyl-2,3-dihydro-1h-indol;1-Acetyl-2,3-dihydro-1H-indole;1H-Indole, 1-acetyl-2,3-dihydro-
CBNumber:
CB5487514
Molecular Formula:
C10H11NO
Molecular Weight:
161.2
MDL Number:
MFCD00022908
MOL File:
16078-30-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:34
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1-Acetylindoline Properties

Melting point 102-104 °C(lit.)
Boiling point 125-130 °C(Press: 1 Torr)
Density 1.144±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 1.13±0.20(Predicted)
Appearance White to light brown Solid
InChI 1S/C10H11NO/c1-8(12)11-7-6-9-4-2-3-5-10(9)11/h2-5H,6-7H2,1H3
InChIKey RNTCWULFNYNFGI-UHFFFAOYSA-N
SMILES CC(=O)N1CCc2ccccc12
CAS DataBase Reference 16078-30-1(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H317
Precautionary statements  P280
Safety Statements  22-24/25
WGK Germany  3
RTECS  NM1892500
HS Code  2933998090
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

1-Acetylindoline price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 379492 1-Acetylindoline 98% 16078-30-1 5g $43.9 2023-06-20 Buy
TCI Chemical A3508 1-(Indolin-1-yl)ethan-1-one min. 95.0 % 16078-30-1 5G $78 2026-04-30 Buy
TCI Chemical A3508 1-(Indolin-1-yl)ethan-1-one min. 95.0 % 16078-30-1 25G $233 2026-04-30 Buy
Usbiological 261001 1-Acetylindoline Asreported 16078-30-1 10g $333 2026-06-03 Buy
Usbiological 261001 1-Acetylindoline Asreported 16078-30-1 25g $483 2026-06-03 Buy
Product number Packaging Price Buy
379492 5g $43.9 Buy
A3508 5G $78 Buy
A3508 25G $233 Buy
261001 10g $333 Buy
261001 25g $483 Buy

1-Acetylindoline Chemical Properties, Uses, Production

Uses

• ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5

Uses

1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.

Uses

  • Reactant for preparation of triazolothiadiazepine dioxide derivatives
  • Reactant for preparation of halo-substituted aromatic amides
  • Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
  • Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
  • Reactant for regioselective ortho Suzuki-Miyaura coupling reaction

Synthesis Reference(s)

Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9
Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1

General Description

1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported.

1-Acetylindoline Preparation Products And Raw materials

Raw materials

Preparation Products

methyl indoline-5-carboxylate 5-Bromo-7-nitroindoline 5-Bromoindoline 5-Acetylindole 1-acetylindoline-5-carbonitrile
1-(7-Bromoindolin-1-yl)ethanone 1H-Indole,7-ethoxy-2,3-dihydro-(9CI) Ethanone, 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-2-[bis(phenylMethyl)aMino]- 1-Acetyl-7-bromoindolin-5-amine 1 5-Diacetylindoline 97

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1-Acetylindoline Suppliers

Global Suppliers ( 212)
Supplier Tel Email Country ProdList Advantage
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
China Langchem Inc. 0086-21-58956006 China 7798 57
Supplier Advantage
INTATRADE GmbH 66
Energy Chemical 61
Capot Chemical Co., Ltd 66
Beijing Ouhe Technology Co., Ltd 60
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Jia Xing Isenchem Co.,Ltd 66
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
China Langchem Inc. 57

View Latest Price from 1-Acetylindoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-ACETYLINDOLINE pictures 2019-08-06 1-ACETYLINDOLINE
16078-30-1
 $1.00 1KG 95-99% 100kg/week Career Henan Chemical Co

1-Acetylindoline Spectrum

1-ACETYLINDOLINE(16078-30-1)1HNMR1-ACETYLINDOLINE(16078-30-1)Raman1-ACETYLINDOLINE(16078-30-1)IR

16078-30-1 (1-Acetylindoline) Related Search:

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Brucine hydrochloride Strychnine Sulfate 1-Acetyl-5-bromo-7-nitroindoline 1-Acetyl-5-nitroindoline 1-Acetylindoline
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1-acetyl-2,3-dihydro-1h-indol 1-acetyl-indolin 1-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE 1-(2,3-DIHYDRO-INDOL-1-YL)-ETHANONE Acetylindoline,N- 1H-Indole, 1-acetyl-2,3-dihydro- (9CI) N-ACETYL INDOLINE 1-ACETYLINDOLINE 98+% 1H-Indole, 1-acetyl-2,3-dihydro- 1-Acetyl-2,3-dihydro-1H-indole Ethanone, 1-(2,3-dihydro-1H-indol-1-yl)- 1-(indolin-1-yl)ethan-1-one 1-ACETYL-2,3-DIHYDROINDOLE 1-Acetylindoline 16078-30-1 Indoles Heterocyclic Building Blocks Building Blocks Building Blocks C10 Chemical Synthesis Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Indoles Indoline & Oxindole ACETYLGROUP Indoles and derivatives