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5-Acetylindole

5-Acetylindole structure

CAS No.: 53330-94-2

Chemical Name:: 5-Acetylindole

Synonyms: 1-(1H-Indol-5-yl)ethan-1-one;5-ACETYLINDOLE;5-ACETYLINDOLE 97+%;5-INDOLYL-METHYLKETONE;ketone,indol-5-ylmethyl;Acetyl-5-indole [French];1-(1H-INDOL-5-YL)-ETHANONE;Ethanone, 1-(1H-indol-5-yl)-;Ethanone, 1-(1H-indol-5-yl)- (9CI);1-(1H-Indol-5-yl)ethan-1-one, 5-Ethanoyl-1H-indole

CBNumber:: CB4171621

Molecular Formula:: C10H9NO

Molecular Weight:: 159.18

MDL Number:: MFCD00481875

MOL File:: 53330-94-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 04:48:55

Product description	Number	Pack Size	Price
5-Acetylindole Asreported	260998	250mg	$408
5-Acetylindole Asreported	260998	500mg	$623
5-Acetylindole ≥97% (NMR) ≥97%(NMR)	233808	250mg	$240
5-Acetylindole Asreported	260998	1g	$887
5-Acetylindole ≥97% (NMR) ≥97%(NMR)	233808	1g	$326
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5-Acetylindole Properties

Melting point	95-96°C
Boiling point	284.68°C (rough estimate)
Density	1.1202 (rough estimate)
refractive index	1.5460 (estimate)
storage temp.	Sealed in dry,Room Temperature
pka	16.06±0.30(Predicted)
Appearance	White to off-white Solid
InChI	InChI=1S/C10H9NO/c1-7(12)8-2-3-10-9(6-8)4-5-11-10/h2-6,11H,1H3
InChIKey	GOFIUEUUROFVMA-UHFFFAOYSA-N
SMILES	C(=O)(C1C=CC2=C(C=1)C=CN2)C
CAS DataBase Reference	53330-94-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39
HS Code	2933998090

5-Acetylindole price More Price(85)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	260998	5-Acetylindole Asreported	53330-94-2	250mg	$408	2026-06-03	Buy
Usbiological	260998	5-Acetylindole Asreported	53330-94-2	500mg	$623	2026-06-03	Buy
Usbiological	233808	5-Acetylindole ≥97% (NMR) ≥97%(NMR)	53330-94-2	250mg	$240	2026-06-03	Buy
Usbiological	260998	5-Acetylindole Asreported	53330-94-2	1g	$887	2026-06-03	Buy
Usbiological	233808	5-Acetylindole ≥97% (NMR) ≥97%(NMR)	53330-94-2	1g	$326	2026-06-03	Buy

Product number	Packaging	Price	Buy
260998	250mg	$408	Buy
260998	500mg	$623	Buy
233808	250mg	$240	Buy
260998	1g	$887	Buy
233808	1g	$326	Buy

5-Acetylindole Chemical Properties,Uses,Production

Uses

5-Acetylindole, is a building block used in various chemical synthesis.

Synthesis

1670-81-1

917-54-4

53330-94-2

Methyl lithium (1.6 M ether solution, 30 mL, 51.2 mmol) was added slowly and dropwise to a solution of anhydrous tetrahydrofuran (30 mL) of indole-5-carboxylic acid (2.5 g, 15.5 mmol) at 0 °C and under nitrogen protection. The reaction mixture was stirred at room temperature for 4 hours before the reaction was quenched with aqueous ammonium chloride solution and extracted with dichloromethane (3 x 50 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 5-acetylindole (1.8 g, white solid).

References

[1] European Journal of Medicinal Chemistry, 2019, p. 428 - 442
[2] Patent: WO2005/26175, 2005, A1. Location in patent: Page/Page column 73
[3] Patent: EP2287173, 2011, A1. Location in patent: Page/Page column 40-41

5-Acetylindole synthesis

Synthesis of 5-Acetylindole from Indole-5-carboxylic acid and Methyllithium

5-Acetylindole Preparation Products And Raw materials

Raw materials

tert-Butyllithium 5-Bromoindole Potassium hydride N,N-Dimethylacetamide 5-Acetyl-indole-3-carboxylic acid

Indole-5-carboxylic acid N-methoxy-N-methyl-1H-indole-5-carboxamide 1-(2,3-DIHYDRO-1H-INDOL-5-YL)-ETHANONE 1-(4-aMino-3-iodophenyl)ethanone 5-ethynyl-1H-indole

1-ACETYLINDOLINE N-Methoxy-N-methylacetamide 3-(TRIFLUOROACETYL)INDOLE Methyllithium 4-Aminoacetophenone

Methylmagnesium Bromide

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Preparation Products

1-(1-Methyl-1H-indol-5-yl)ethanone

5-Acetylindole Suppliers

Global( 120)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Nanjing jinheyou Trading Co., Ltd.	15705188088	admin@jheyou.com	CHINA	1268	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3991	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52704	58
Hong Kong Tiansheng New Material Trading Co., Ltd	+8617320695765	zxx@hktiansheng.com	China	973	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Wuhan Chemwish Technology Co., Ltd	58
Nanjing jinheyou Trading Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hong Kong Tiansheng New Material Trading Co., Ltd	58

View Lastest Price from 5-Acetylindole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-02-25	1-(1H-Indol-5-yl)ethanone 53330-94-2	$100.00	1KG	99%	100kg	Hong Kong Tiansheng New Material Trading Co., Ltd
2022-02-25	1-(1H-Indol-5-yl)ethanone 53330-94-2	$100.00	1KG	98%	100KG	Hong Kong Tiansheng New Material Trading Co., Ltd
2019-12-25	5-Acetylindole 53330-94-2	$1.00	1KG	99%		Career Henan Chemical Co

1-(1H-Indol-5-yl)ethanone
53330-94-2
$100.00
99%
Hong Kong Tiansheng New Material Trading Co., Ltd

1-(1H-Indol-5-yl)ethanone
53330-94-2
$100.00
98%
Hong Kong Tiansheng New Material Trading Co., Ltd

5-Acetylindole
53330-94-2
$1.00
99%
Career Henan Chemical Co

5-Acetylindole Spectrum

5-Acetylindole(53330-94-2)¹HNMR

53330-94-2(5-Acetylindole)Related Search:

Indole-3-acetic acid Indole-3-butyric acid Indometacin L-PICEIN 3-ACETOXY-5-BROMOINDOLE

Acetylindole,L-Acetylindole,1-ACETYLINDOLE,N-ACETYLINDOLE l-acetylindole-3-carboxaldehyde,N-ACETYLINDOLE-3-ALDEHYDE,1-ACETYLINDOLE-3-CARBOXALDEHYDE,N-ACETYLINDOLE-3-CARBOXALDEHYDE,1-ACETYLINDOLE-3-CARBALDEHYDE 3-Acetylindole 1-(6-CHLORO-9-METHYL-9H-CARBAZOL-3-YL)-ETHANONE 3,6-Diacetyl-9-methyl-9H-carbazole

LOLITREM B 5-ACETYL-3-METHYL-1H-INDOLE-2-CARBOXYLIC ACID VAT BLACK 27 5-ACETYL-2-INDOLE CARBOXYLIC ACID Acetryptine

3-Acetylcarbazole 1-(9-Methyl-9H-carbazol-3-yl)-ethanone 3,6-BIS(2-METHYL-2-MORPHOLINOPROPIONYL)-9-OCTYLCARBAZOLE

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5-ACETYLINDOLE 97+% Ethanone, 1-(1H-indol-5-yl)- (9CI) Ethanone, 1-(1H-indol-5-yl)- 1-(1H-Indol-5-yl)ethan-1-one, 5-Ethanoyl-1H-indole ketone,indol-5-ylmethyl 1-(1H-INDOL-5-YL)-ETHANONE 5-INDOLYL-METHYLKETONE 5-ACETYLINDOLE Acetyl-5-indole [French] 1-(1H-Indol-5-yl)ethan-1-one 53330-94-2 5330-94-2 ACETYLGROUP Indoles and derivatives