L 741626
- CAS No.
- 81226-60-0
- Chemical Name:
- L 741626
- Synonyms
- L-741626, 10 mM in DMSO;L-741,626, D2 antagonist;3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL;4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-;receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit
- CBNumber:
- CB61320787
- Molecular Formula:
- C20H21ClN2O
- Molecular Weight:
- 340.85
- MDL Number:
- MFCD00953632
- MOL File:
- 81226-60-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 548.8±50.0 °C(Predicted) |
|---|---|
| Density | 1.311±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: ≥20mg/mL |
| form | powder |
| pka | 13.87±0.20(Predicted) |
| color | white to beige |
| InChI | 1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 |
| InChIKey | LLBLNMUONVVVPG-UHFFFAOYSA-N |
| SMILES | OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4 |
| FDA UNII | WTW4A6SW92 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
L 741626 price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | L135 | L-741,626 ≥98% (HPLC) | 81226-60-0 | 10mg | $179 | 2026-04-30 | Buy |
| Sigma-Aldrich | L135 | L-741,626 ≥98% (HPLC) | 81226-60-0 | 50mg | $753 | 2026-04-30 | Buy |
| Sigma-Aldrich | 5.05879 | L-741,626 - CAS 81226-60-0 - Calbiochem | 81226-60-0 | 10mg | $146 | 2022-05-15 | Buy |
| Cayman Chemical | 22354 | L-741,626 ≥98% | 81226-60-0 | 5mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 22354 | L-741,626 ≥98% | 81226-60-0 | 10mg | $128 | 2026-04-30 | Buy |
L 741626 Chemical Properties, Uses, Production
Uses
L-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists.
Uses
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
Definition
ChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines.
Hazard
A poison.
Biochem/physiol Actions
L-741,626 is a selective dopamine (D2) receptor antagonist.
storage
Store at RT
L 741626 Preparation Products And Raw materials
Raw materials
Preparation Products
L 741626 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2981 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| ShangHai Movin Pharmaceutical Co., Ltd. | 13681854265 | info@moenpharm.com | China | 488 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 87240 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9769 | 55 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | sales@linyuepharm.com | China | 5762 | 55 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
